8CRG

E. coli adenylate kinase in complex with two ADP molecules as a result of enzymatic AP4A hydrolysis

Summary for 8CRG

Entry DOI	10.2210/pdb8crg/pdb
Descriptor	Adenylate kinase, ADENOSINE-5'-DIPHOSPHATE, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, ... (4 entities in total)
Functional Keywords	phosphotransferase, energy metabolism, ap4a hydrolysis, potential moonlighting protein, transferase
Biological source	Escherichia coli K-12
Total number of polymer chains	2
Total formula weight	49158.12
Authors	Oelker, M.,Tischlik, S.,Wolf-Watz, M.,Sauer-Eriksson, A.E. (deposition date: 2023-03-08, release date: 2023-06-14, Last modification date: 2023-10-25)
Primary citation	Tischlik, S.,Oelker, M.,Rogne, P.,Sauer-Eriksson, A.E.,Drescher, M.,Wolf-Watz, M. Insights into Enzymatic Catalysis from Binding and Hydrolysis of Diadenosine Tetraphosphate by E. coli Adenylate Kinase. Biochemistry, 62:2238-2243, 2023 Cited by PubMed: 37418448 DOI: 10.1021/acs.biochem.3c00189 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.49 Å)

Structure validation