3A62
| Crystal structure of phosphorylated p70S6K1 | 分子名称: | MANGANESE (II) ION, Ribosomal protein S6 kinase beta-1, STAUROSPORINE | 著者 | Sunami, T, Byrne, N, Diehl, R.E, Funabashi, K, Hall, D.L, Ikuta, M, Patel, S.B, Shipman, J.M, Smith, R.F, Takahashi, I, Zugay-Murphy, J, Iwasawa, Y, Lumb, K.J, Munshi, S.K, Sharma, S. | 登録日 | 2009-08-18 | 公開日 | 2009-10-27 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural basis of human p70 ribosomal S6 kinase-1 regulation by activation loop phosphorylation. J.Biol.Chem., 285, 2010
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2OE6
| 2.4A X-ray crystal structure of unliganded RNA fragment GGGCGUCGCUAGUACC/CGGUACUAAAAGUCGCC containing the human ribosomal decoding A site: RNA construct with 5'-overhang | 分子名称: | RNA (5'-R(*CP*GP*GP*UP*AP*CP*UP*AP*AP*AP*AP*GP*UP*CP*GP*CP*C)-3'), RNA (5'-R(*GP*GP*GP*CP*GP*UP*CP*GP*CP*UP*AP*GP*UP*AP*CP*C)-3') | 著者 | Hermann, T, Tereshko, V, Skripkin, E, Patel, D.J. | 登録日 | 2006-12-28 | 公開日 | 2007-02-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Apramycin recognition by the human ribosomal decoding site. Blood Cells Mol.Dis., 38, 2007
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5T3K
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7YFS
| The NMR structure of noursin, a tricyclic ribosomal peptide containing a histidine-to-butyrine crosslink | 分子名称: | noursin | 著者 | Yao, H, Li, Y, Zhang, T, Gao, J, Wang, H. | 登録日 | 2022-07-09 | 公開日 | 2023-05-31 | 最終更新日 | 2024-05-08 | 実験手法 | SOLUTION NMR | 主引用文献 | Discovery and biosynthesis of tricyclic copper-binding ribosomal peptides containing histidine-to-butyrine crosslinks. Nat Commun, 14, 2023
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8EQ5
| Crystal structure of the N-terminal kinase domain of RSK2 in complex with SPRED2 (131-160) | 分子名称: | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside, Ribosomal protein S6 kinase alpha-3, Sprouty-related, ... | 著者 | Bonsor, D.A, Lopez, J, McCormick, F, Simanshu, D.K. | 登録日 | 2022-10-07 | 公開日 | 2023-04-26 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The ribosomal S6 kinase 2 (RSK2)-SPRED2 complex regulates the phosphorylation of RSK substrates and MAPK signaling. J.Biol.Chem., 299, 2023
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4EL9
| Structure of N-terminal kinase domain of RSK2 with afzelin | 分子名称: | 5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 6-deoxy-alpha-L-mannopyranoside, Ribosomal protein S6 kinase alpha-3 | 著者 | Utepbergenov, D, Derewenda, U, Derewenda, Z.S. | 登録日 | 2012-04-10 | 公開日 | 2012-09-05 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Insights into the Inhibition of the p90 Ribosomal S6 Kinase (RSK) by the Flavonol Glycoside SL0101 from the 1.5 A Crystal Structure of the N-Terminal Domain of RSK2 with Bound Inhibitor. Biochemistry, 51, 2012
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1K5I
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2BH2
| Crystal Structure of E. coli 5-methyluridine methyltransferase RumA in complex with ribosomal RNA substrate and S-adenosylhomocysteine. | 分子名称: | 23S RIBOSOMAL RNA 1932-1968, 23S RRNA (URACIL-5-)-METHYLTRANSFERASE RUMA, IRON/SULFUR CLUSTER, ... | 著者 | Lee, T.T, Agarwalla, S, Stroud, R.M. | 登録日 | 2005-01-06 | 公開日 | 2005-03-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | A Unique RNA Fold in the Ruma-RNA-Cofactor Ternary Complex Contributes to Substrate Selectivity and Enzymatic Function Cell(Cambridge,Mass.), 120, 2005
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3IGR
| The Crystal Structure of Ribosomal-protein-S5-alanine Acetyltransferase from Vibrio fischeri to 2.0A | 分子名称: | GLYCEROL, Ribosomal-protein-S5-alanine N-acetyltransferase, SODIUM ION | 著者 | Stein, A.J, Sather, A, Shackelford, G, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | 登録日 | 2009-07-28 | 公開日 | 2009-09-01 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The Crystal Structure of Ribosomal-protein-S5-alanine Acetyltransferase from Vibrio fischeri to 2.0A To be Published
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437D
| CRYSTAL STRUCTURE OF AN RNA PSEUDOKNOT FROM BEET WESTERN YELLOW VIRUS INVOLVED IN RIBOSOMAL FRAMESHIFTING | 分子名称: | MAGNESIUM ION, RNA PSEUDOKNOT, SODIUM ION | 著者 | Su, L, Chen, L, Egli, M, Berger, J.M, Rich, A. | 登録日 | 1998-11-24 | 公開日 | 1998-12-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Minor groove RNA triplex in the crystal structure of a ribosomal frameshifting viral pseudoknot. Nat.Struct.Biol., 6, 1999
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4JXJ
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7KW3
| Non Ribosomal PCP domain | 分子名称: | PCP domain, SULFATE ION | 著者 | Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. | 登録日 | 2020-11-29 | 公開日 | 2021-03-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nat Commun, 12, 2021
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7KW0
| Non-ribosomal didomain (stabilised glycine-PCP-C) acceptor bound state | 分子名称: | N-{2-[(2-aminoethyl)sulfanyl]ethyl}-N~3~-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alaninamide, PCP-C didomain | 著者 | Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. | 登録日 | 2020-11-29 | 公開日 | 2021-03-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nat Commun, 12, 2021
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7KVW
| Non-ribosomal didomain (holo-PCP-C) acceptor bound state | 分子名称: | 4'-PHOSPHOPANTETHEINE, PCP-C didomain | 著者 | Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. | 登録日 | 2020-11-29 | 公開日 | 2021-03-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nat Commun, 12, 2021
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7KW2
| Non-ribosomal didomain (holo-PCP-C) acceptor bound state, R2577G | 分子名称: | 4'-PHOSPHOPANTETHEINE, PCP-C didomain | 著者 | Izore, T, Ho, Y.T.C, Kaczmarski, J.A, Gavriilidou, A, Chow, K.H, Steer, D, Goode, R.J.A, Schittenhelm, R.B, Tailhades, J, Tosin, M, Challis, G.L, Krenske, E.H, Ziemert, N, Jackson, C.J, Cryle, M.J. | 登録日 | 2020-11-29 | 公開日 | 2021-03-24 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nat Commun, 12, 2021
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3UZU
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1QHK
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2A43
| Crystal Structure of a Luteoviral RNA Pseudoknot and Model for a Minimal Ribosomal Frameshifting Motif | 分子名称: | MAGNESIUM ION, RNA Pseudoknot | 著者 | Pallan, P.S, Marshall, W.S, Harp, J, Jewett III, F.C, Wawrzak, Z, Brown II, B.A, Rich, A, Egli, M. | 登録日 | 2005-06-27 | 公開日 | 2005-09-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | Crystal Structure of a Luteoviral RNA Pseudoknot and Model for a Minimal Ribosomal Frameshifting Motif Biochemistry, 44, 2005
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2JSE
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1E95
| Solution structure of the pseudoknot of SRV-1 RNA, involved in ribosomal frameshifting | 分子名称: | RNA (5'-(*GP*CP*GP*GP*CP*CP*AP*GP*CP*UP*CP* CP*AP*GP*GP*CP*CP*GP*CP*CP*AP*AP*AP*CP* AP*AP*UP*AP*UP*GP*GP*AP*GP*CP*AP*C)-3') | 著者 | Michiels, P.J.A, Versleyen, A, Pleij, C.W.A, Hilbers, C.W, Heus, H.A. | 登録日 | 2000-10-09 | 公開日 | 2001-08-23 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Pseudoknot of Srv-1 RNA, Involved in Ribosomal Frameshifting J.Mol.Biol., 310, 2001
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6L63
| Human Coagulation Factor XIIa (FXIIa) bound with the macrocyclic peptide F3 containing two (1S,2S)-2-ACHC residues | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYL GROUP, ... | 著者 | Sengoku, T, Katoh, T, Hirata, K, Suga, H, Ogata, K. | 登録日 | 2019-10-26 | 公開日 | 2020-09-02 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Ribosomal synthesis and de novo discovery of bioactive foldamer peptides containing cyclic beta-amino acids. Nat.Chem., 12, 2020
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2BM1
| Ribosomal elongation factor G (EF-G) Fusidic acid resistant mutant G16V | 分子名称: | ELONGATION FACTOR G, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Hansson, S, Singh, R, Gudkov, A.T, Liljas, A, Logan, D.T. | 登録日 | 2005-03-09 | 公開日 | 2005-05-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structural Insights Into Fusidic Acid Resistance and Sensitivity in EF-G J.Mol.Biol., 348, 2005
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2BM0
| Ribosomal elongation factor G (EF-G) Fusidic acid resistant mutant T84A | 分子名称: | ELONGATION FACTOR G, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | 著者 | Hansson, S, Singh, R, Gudkov, A.T, Liljas, A, Logan, D.T. | 登録日 | 2005-03-09 | 公開日 | 2005-05-04 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural Insights Into Fusidic Acid Resistance and Sensitivity in EF-G J.Mol.Biol., 348, 2005
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7AOI
| Trypanosoma brucei mitochondrial ribosome large subunit assembly intermediate | 分子名称: | 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L17, ... | 著者 | Tobiasson, V, Gahura, O, Aibara, S, Baradaran, R, Zikova, A, Amunts, A. | 登録日 | 2020-10-14 | 公開日 | 2020-12-02 | 最終更新日 | 2021-03-24 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit. Embo J., 40, 2021
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3DH3
| Crystal Structure of RluF in complex with a 22 nucleotide RNA substrate | 分子名称: | Ribosomal large subunit pseudouridine synthase F, stem loop fragment of E. Coli 23S RNA | 著者 | Alian, A, DeGiovanni, A, Stroud, R.M, Finer-Moore, J.S. | 登録日 | 2008-06-16 | 公開日 | 2009-04-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structure of an RluF-RNA complex: a base-pair rearrangement is the key to selectivity of RluF for U2604 of the ribosome. J.Mol.Biol., 388, 2009
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