6L63

Human Coagulation Factor XIIa (FXIIa) bound with the macrocyclic peptide F3 containing two (1S,2S)-2-ACHC residues

Summary for 6L63

• Entry DOI: 10.2210/pdb6l63/pdb
• Related PRD ID: PRD_900017
• Descriptor: Coagulation factor XII, F3, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: enzyme, blood clotting
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 57925.96

Authors

Sengoku, T.,Katoh, T.,Hirata, K.,Suga, H.,Ogata, K. (deposition date: 2019-10-26, release date: 2020-09-02, Last modification date: 2023-11-22)

• Primary citation: Katoh, T.,Sengoku, T.,Hirata, K.,Ogata, K.,Suga, H.; Ribosomal synthesis and de novo discovery of bioactive foldamer peptides containing cyclic beta-amino acids.; Nat.Chem., 12:1081-1088, 2020; PubMed: 32839601; DOI: 10.1038/s41557-020-0525-1

Experimental method

X-RAY DIFFRACTION (3 Å)