Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5HVB
DownloadVisualize
BU of 5hvb by Molmil
5-methyl-6-(1-naphthylthio)thieno[2,3-d]pyrimidine 2,4-diamine
分子名称: 5-methyl-6-(naphthalen-1-ylsulfanyl)thieno[2,3-d]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Cody, V.
登録日2016-01-28
公開日2017-02-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Human dihydrofolate reductase ternary complex with a series of fluorine substituted 5-methyl-6-(1-napthylthio)[2,3-d]pyrimidine-2,4-diamines
To Be Published
5GAG
DownloadVisualize
BU of 5gag by Molmil
RNC in complex with SRP-SR in the closed state
分子名称: 1A9L SS, 23S rRNA, 50S ribosomal protein L10, ...
著者Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N.
登録日2015-11-26
公開日2016-01-27
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon.
Nat Commun, 7, 2016
8OW1
DownloadVisualize
BU of 8ow1 by Molmil
Cryo-EM structure of the yeast Inner kinetochore bound to a CENP-A nucleosome.
分子名称: C0N3, Centromere DNA-binding protein complex CBF3 subunit B, Centromere DNA-binding protein complex CBF3 subunit C, ...
著者Dendooven, T.D, Zhang, Z, Yang, J, McLaughlin, S, Schwabb, J, Scheres, S, Yatskevich, S, Barford, D.
登録日2023-04-26
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.
Sci Adv, 9, 2023
4L8H
DownloadVisualize
BU of 4l8h by Molmil
Bacteriophage Qbeta coat protein in complex with RNA operator hairpin
分子名称: Coat protein, RNA operator hairpin, ZINC ION
著者Rumnieks, J, Tars, K.
登録日2013-06-17
公開日2013-10-02
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of the bacteriophage q beta coat protein in complex with the RNA operator of the replicase gene.
J.Mol.Biol., 426, 2014
5GAF
DownloadVisualize
BU of 5gaf by Molmil
RNC in complex with SRP
分子名称: 1A9L SS, 23S ribosomal RNA, 50S ribosomal protein L10, ...
著者Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N.
登録日2015-11-25
公開日2016-02-03
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon
Nat Commun, 7, 2016
5GAH
DownloadVisualize
BU of 5gah by Molmil
RNC in complex with SRP with detached NG domain
分子名称: 1A9L SS, 23S rRNA, 50S ribosomal protein L10, ...
著者Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N.
登録日2015-11-26
公開日2016-01-27
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon.
Nat Commun, 7, 2016
5GAD
DownloadVisualize
BU of 5gad by Molmil
RNC-SRP-SR complex early state
分子名称: 1A9L SS, 23S rRNA, 50S ribosomal protein L10, ...
著者Jomaa, A, Boehringer, D, Leibundgut, M, Ban, N.
登録日2015-11-24
公開日2016-01-27
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structures of the E. coli translating ribosome with SRP and its receptor and with the translocon.
Nat Commun, 7, 2016
4MCX
DownloadVisualize
BU of 4mcx by Molmil
P. vulgaris HIGBA structure, crystal form 2
分子名称: Antidote protein, Killer protein
著者Schureck, M.A, Maehigashi, T, Dunham, C.M.
登録日2013-08-21
公開日2013-12-11
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of the Proteus vulgaris HigB-(HigA)2-HigB Toxin-Antitoxin Complex.
J.Biol.Chem., 289, 2014
8J6W
DownloadVisualize
BU of 8j6w by Molmil
Full length crystal structure of Escherichia coli Fur
分子名称: Ferric uptake regulation protein, ZINC ION
著者Zhang, F, Wang, X, Gu, L.
登録日2023-04-26
公開日2024-05-01
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Full length crystal structure of Escherichia coli Fur
To Be Published
3N5G
DownloadVisualize
BU of 3n5g by Molmil
Crystal Structure of histidine-tagged human thymidylate synthase
分子名称: SULFATE ION, Thymidylate synthase
著者Pozzi, C, Cardinale, D, Guaitoli, G, Tondi, D, Luciani, R, Myllykallio, H, Ferrari, S, Costi, M.P, Mangani, S.
登録日2010-05-25
公開日2011-06-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Protein-protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase.
Proc.Natl.Acad.Sci.USA, 108, 2011
6LA8
DownloadVisualize
BU of 6la8 by Molmil
349 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0
分子名称: CALCIUM ION, DNA (349-MER), Histone H1.0, ...
著者Adhireksan, Z, Lee, P.L, Sharma, D, Davey, C.A.
登録日2019-11-12
公開日2020-10-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Near-atomic resolution structures of interdigitated nucleosome fibres.
Nat Commun, 11, 2020
6LA9
DownloadVisualize
BU of 6la9 by Molmil
349 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 (high cryoprotectant)
分子名称: CALCIUM ION, DNA (349-MER), Histone H1.0, ...
著者Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A.
登録日2019-11-12
公開日2020-10-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Near-atomic resolution structures of interdigitated nucleosome fibres.
Nat Commun, 11, 2020
6LDM
DownloadVisualize
BU of 6ldm by Molmil
Structural basis of G-quadruplex DNA recognition by the yeast telomeric protein Rap1
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA-binding protein RAP1, G-guadruplex DNA, ...
著者Traczyk, A, Gill, D.J, Chong, W.L, Rhodes, D.
登録日2019-11-22
公開日2020-03-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of G-quadruplex DNA recognition by the yeast telomeric protein Rap1.
Nucleic Acids Res., 48, 2020
6LAB
DownloadVisualize
BU of 6lab by Molmil
169 bp nucleosome, harboring cohesive DNA termini, assembled with linker histone H1.0
分子名称: CALCIUM ION, CHLORIDE ION, DNA (169-MER), ...
著者Adhireksan, Z, Sharma, D, Bao, Q, Lee, P.L, Padavattan, S, Davey, C.A.
登録日2019-11-12
公開日2021-02-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Engineering nucleosomes for generating diverse chromatin assemblies.
Nucleic Acids Res., 49, 2021
6LA2
DownloadVisualize
BU of 6la2 by Molmil
343 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0
分子名称: DNA (343-MER), Histone H1.0, Histone H2A type 1-B/E, ...
著者Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A.
登録日2019-11-11
公開日2021-02-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.89 Å)
主引用文献Engineering nucleosomes for generating diverse chromatin assemblies.
Nucleic Acids Res., 49, 2021
6M5W
DownloadVisualize
BU of 6m5w by Molmil
Co-crystal structure of human serine hydroxymethyltransferase 1 in complex with Pyridoxal 5'-phosphate (PLP) and glycodeoxycholic acid
分子名称: (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, GLYCINE, PYRIDOXAL-5'-PHOSPHATE, ...
著者Ota, T, Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K, Sando, S.
登録日2020-03-11
公開日2021-01-20
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for selective inhibition of human serine hydroxymethyltransferase by secondary bile acid conjugate.
Iscience, 24, 2021
6MRK
DownloadVisualize
BU of 6mrk by Molmil
Crystal structure of dmNxf2 NTF2-like domain in complex with Nxt1/p15
分子名称: NTF2-related export protein, Nuclear RNA export factor 2
著者Wang, J, Patel, D.J.
登録日2018-10-13
公開日2019-07-03
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation.
Nat.Struct.Mol.Biol., 26, 2019
6MRJ
DownloadVisualize
BU of 6mrj by Molmil
Crystal structure of H.pylori NikR in complex with DNA
分子名称: DNA (36-MER), MAGNESIUM ION, NICKEL (II) ION, ...
著者Pozharski, E, de Serrano, V.
登録日2018-10-13
公開日2019-11-20
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of H.pylori NikR in complex with DNA
To Be Published
3KH2
DownloadVisualize
BU of 3kh2 by Molmil
Crystal structure of the P1 bacteriophage Doc toxin (F68S) in complex with the Phd antitoxin (L17M/V39A). Northeast Structural Genomics targets ER385-ER386
分子名称: 2-HYDROXYETHYL DISULFIDE, CHLORIDE ION, Death on curing protein, ...
著者Arbing, M.A, Kuzin, A.P, Su, M, Abashidze, M, Verdon, G, Liu, M, Xiao, R, Acton, T, Inouye, M, Montelione, G.T, Woychik, N.A, Hunt, J.F, Northeast Structural Genomics Consortium (NESG)
登録日2009-10-29
公開日2010-08-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献Crystal Structures of Phd-Doc, HigA, and YeeU Establish Multiple Evolutionary Links between Microbial Growth-Regulating Toxin-Antitoxin Systems.
Structure, 18, 2010
3LLR
DownloadVisualize
BU of 3llr by Molmil
Crystal structure of the PWWP domain of Human DNA (cytosine-5-)-methyltransferase 3 alpha
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DNA (cytosine-5)-methyltransferase 3A, SULFATE ION
著者Qiu, W, Dombrovski, L, Ni, S, Weigelt, J, Boutra, C, Arrowsmith, C.H, Edwards, A.M, Min, J, Wu, H, Structural Genomics Consortium (SGC)
登録日2010-01-29
公開日2010-03-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural and histone binding ability characterizations of human PWWP domains.
Plos One, 6, 2011
3LGH
DownloadVisualize
BU of 3lgh by Molmil
Crystal structure of NikR from Helicobacter pylori with variable Ni site coordination
分子名称: MAGNESIUM ION, NICKEL (II) ION, nickel-responsive regulator
著者Pozharski, E, St John, F.
登録日2010-01-20
公開日2010-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Holo-Ni(II)HpNikR Is an Asymmetric Tetramer Containing Two Different Nickel-Binding Sites.
J.Am.Chem.Soc., 132, 2010
2AY0
DownloadVisualize
BU of 2ay0 by Molmil
Structure of the Lys9Met mutant of the E. coli Proline Utilization A (PutA) DNA-binding domain.
分子名称: Bifunctional putA protein, CHLORIDE ION
著者Larson, J.D, Schuermann, J.P, Zhou, Y, Jenkins, J.L, Becker, D.F, Tanner, J.J.
登録日2005-09-06
公開日2006-08-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structures of the DNA-binding domain of Escherichia coli proline utilization A flavoprotein and analysis of the role of Lys9 in DNA recognition.
Protein Sci., 15, 2006
5SDA
DownloadVisualize
BU of 5sda by Molmil
Crystal Structure of Dihydrofolate Reductase from Homo sapiens bound to NADP and SDDC Inhibitor SDDC-774
分子名称: (2R)-3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-2-methylpropanamide, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-12-20
公開日2022-02-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Crystal Structure of Dihydrofolate Reductase from Homo sapiens bound to NADP and SDDC Inhibitor SDDC-774
to be published
5SD7
DownloadVisualize
BU of 5sd7 by Molmil
Crystal Structure of Dihydrofolate Reductase from Homo sapiens bound to NADP and SDDC Inhibitor SDDC-735
分子名称: (2S)-3-(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)-2-methylpropanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-12-20
公開日2022-02-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of Dihydrofolate Reductase from Homo sapiens bound to NADP and SDDC Inhibitor SDDC-735
to be published
5SD9
DownloadVisualize
BU of 5sd9 by Molmil
Crystal Structure of Dihydrofolate Reductase from Homo sapiens bound to NADP and SDDC Inhibitor SDDC-1096
分子名称: (2S)-2-[(2-{3-[(2,4-diamino-6-ethylpyrimidin-5-yl)oxy]propoxy}phenyl)methyl]-3-fluoropropanoic acid, 1,2-ETHANEDIOL, Dihydrofolate reductase, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-12-20
公開日2022-02-09
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Dihydrofolate Reductase from Homo sapiens bound to NADP and SDDC Inhibitor SDDC-1096
to be published

222926

件を2024-07-24に公開中

PDB statisticsPDBj update infoContact PDBjnumon