PDB: 326 件ウェブページステータス検索Chemie searchBIRD

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6KON	Mycobacterium tuberculosis initial transcription complex comprising sigma H and 5'-OH RNA of 5 nt 分子名称: DNA (5'-D(P*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*GP*TP*G)-3'), DNA (5'-D(P*GP*TP*TP*GP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Li, L, Zhang, Y. 登録日 2019-08-12 公開日 2020-03-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
6LDI	The cryo-EM structure of E. coli CueR transcription activation complex 分子名称: DNA (50-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Fang, C.L, Zhang, Y. 登録日 2019-11-21 公開日 2020-09-30 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.69 Å) 主引用文献 CueR activates transcription through a DNA distortion mechanism. Nat.Chem.Biol., 17, 2021
6LTS	Crystal structure of Thermus thermophilus transcription initiation complex comprising a truncated sigma finger 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Zhang, Y, Ebright, R.H. 登録日 2020-01-23 公開日 2020-03-11 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
6M7J	Mycobacterium tuberculosis RNAP with RbpA/us fork and Corallopyronin 分子名称: DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. 登録日 2018-08-20 公開日 2018-11-21 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
6N62	Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. 登録日 2018-11-24 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.803 Å) 主引用文献 Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6N57	Cryo-EM structure of Escherichia coli RNAP polymerase bound with TraR in conformation I 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2018-11-21 公開日 2020-02-26 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
6N58	Cryo-EM structure of Escherichia coli RNAP polymerase bound with TraR in conformation II 分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. 登録日 2018-11-21 公開日 2020-02-26 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
6N60	Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Microcin J25 (MccJ25) 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. 登録日 2018-11-23 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.68 Å) 主引用文献 Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
7DY6	A refined cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA 分子名称: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Lin, W. 登録日 2021-01-20 公開日 2021-11-17 最終更新日 2024-06-05 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 A unique binding between SspA and RNAP beta' NTH across low-GC Gram-negative bacteria facilitates SspA-mediated transcription regulation. Biochem.Biophys.Res.Commun., 583, 2021
7F75	Cryo-EM structure of Spx-dependent transcription activation complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Lin, W, Feng, Y, Shi, J. 登録日 2021-06-28 公開日 2021-10-13 最終更新日 2022-02-16 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural basis of transcription activation by the global regulator Spx. Nucleic Acids Res., 49, 2021
6N4C	EM structure of the DNA wrapping in bacterial open transcription initiation complex 分子名称: DNA (94-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Florez-Ariza, A, Cassago, A, de Oliveira, P.S.L, Guerra, D.G, Portugal, R.V. 登録日 2018-11-19 公開日 2020-05-27 実験手法 ELECTRON MICROSCOPY (17 Å) 主引用文献 Interactions of Upstream and Downstream Promoter Regions with RNA Polymerase are Energetically Coupled and a Target of Regulation in Transcription Initiation Biorxiv, 2020
6N61	Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Capistruin 分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Capistruin, ... 著者 Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. 登録日 2018-11-24 公開日 2019-01-09 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.253 Å) 主引用文献 Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
7BEG	Structures of class I bacterial transcription complexes 分子名称: Class I pacrA promoter non-template DNA, Class I pacrA promoter template DNA, DNA-directed RNA polymerase subunit alpha, ... 著者 Ye, F.Z, Hao, M, Zhang, X.D. 登録日 2020-12-23 公開日 2021-12-01 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation. Adv Sci, 9, 2022
7BEF	Structures of class II bacterial transcription complexes 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Hao, M, Ye, F.Z, Zhang, X.D. 登録日 2020-12-23 公開日 2021-12-01 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation. Adv Sci, 9, 2022
7F0R	Cryo-EM structure of Pseudomonas aeruginosa SutA transcription activation complex 分子名称: DNA (70-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 He, D.W, You, L.L, Zhang, Y. 登録日 2021-06-06 公開日 2022-07-27 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Pseudomonas aeruginosa SutA wedges RNAP lobe domain open to facilitate promoter DNA unwinding. Nat Commun, 13, 2022
7EH0	Thermus thermophilus RNA polymerase transcription initiation complex containing a template-strand purine at position TSS-2, UpA RNA primer and CMPcPP 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (27-MER), DNA (5'-D(*CP*C*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*AP*AP*AP*G)-3'), ... 著者 Li, L, Zhang, Y. 登録日 2021-03-27 公開日 2021-07-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.808 Å) 主引用文献 Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
7EH2	Thermus thermophilus transcription initiation complex containing a template-strand pyrimidine at position TSS-2 and GpG RNA primer 分子名称: DNA (27-MER), DNA (5'-D(*CP*C*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Li, L, Zhang, Y. 登録日 2021-03-27 公開日 2021-07-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.34 Å) 主引用文献 Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
7EH1	Thermus thermophilus transcription initiation complex containing a template-strand purine at position TSS-2, GpG RNA primer, and CMPcPP 分子名称: 1,4-BUTANEDIOL, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (27-MER), ... 著者 Li, L, Zhang, Y. 登録日 2021-03-27 公開日 2021-07-14 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli . Proc.Natl.Acad.Sci.USA, 118, 2021
4KI2	Crystallographic analysis of an RNA-polymerase sigma-subunit fragment complexed with -10 promoter element ssDNA 分子名称: DNA (5'-D(*TP*GP*TP*AP*CP*AP*AP*TP*GP*GP*G)-3'), POTASSIUM ION, RNA polymerase sigma factor 著者 Feklistov, A, Darst, S.A. 登録日 2013-05-01 公開日 2013-09-04 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Crystallographic analysis of an RNA polymerase sigma-subunit fragment complexed with -10 promoter element ssDNA: quadruplex formation as a possible tool for engineering crystal contacts in protein-ssDNA complexes. Acta Crystallogr.,Sect.F, 69, 2013
4LK1	Crystal Structure Analysis of the E.coli holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Bae, B, Darst, S.A. 登録日 2013-07-05 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.8369 Å) 主引用文献 Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
4LK0	Crystal Structure Analysis of the E.coli holoenzyme/T7 Gp2 complex 分子名称: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Bae, B, Darst, S.A. 登録日 2013-07-05 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.9103 Å) 主引用文献 Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
4MEY	Crystal structure of Escherichia coli RNA polymerase holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H. 登録日 2013-08-27 公開日 2014-05-21 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.948 Å) 主引用文献 Transcription inhibition by the depsipeptide antibiotic salinamide A. Elife, 3, 2014
4LLG	Crystal Structure Analysis of the E.coli holoenzyme/Gp2 complex 分子名称: Bacterial RNA polymerase inhibitor, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Bae, B, Darst, S.A. 登録日 2013-07-09 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.7936 Å) 主引用文献 Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
4LJZ	Crystal Structure Analysis of the E.coli holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Bae, B, Darst, S.A. 登録日 2013-07-05 公開日 2013-11-13 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3.5871 Å) 主引用文献 Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1. Proc.Natl.Acad.Sci.USA, 110, 2013
4MQ9	Crystal structure of Thermus thermophilus RNA polymerase holoenzyme in complex with GE23077 分子名称: (2Z)-2-methylbut-2-enoic acid, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Ho, M.X, Arnold, E, Ebright, R.H, Zhang, Y, Tuske, S. 登録日 2013-09-16 公開日 2014-05-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife, 3, 2014

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