3I5V
 
 | |
1ATN
 | | Atomic structure of the actin:DNASE I complex | | 分子名称: | ACTIN, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ... | | 著者 | Kabsch, W, Mannherz, H.G, Suck, D, Pai, E, Holmes, K.C. | | 登録日 | 1991-03-08 | | 公開日 | 1992-07-15 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Atomic structure of the actin:DNase I complex.
Nature, 347, 1990
|
|
7N94
 | | LINE-1 endonuclease domain complex with DNA | | 分子名称: | DNA (5'-D(*AP*GP*CP*CP*CP*TP*TP*AP*AP*AP*AP*AP*GP*GP*AP*GP*CP*T)-3'), DNA (5'-D(*GP*CP*TP*CP*CP*TP*TP*TP*TP*TP*AP*AP*GP*GP*GP*CP*TP*A)-3'), LINE-1 retrotransposable element ORF2 protein | | 著者 | Korolev, S, Miller, I. | | 登録日 | 2021-06-16 | | 公開日 | 2021-10-13 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Structural dissection of sequence recognition and catalytic mechanism of human LINE-1 endonuclease.
Nucleic Acids Res., 49, 2021
|
|
1DE8
 | | HUMAN APURINIC/APYRIMIDINIC ENDONUCLEASE-1 (APE1) BOUND TO ABASIC DNA | | 分子名称: | DNA (5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*CP*(3DR)P*GP*AP*TP*CP*G)-3'), MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE | | 著者 | Mol, C.D, Izumi, T, Mitra, S, Tainer, J.A. | | 登録日 | 1999-11-13 | | 公開日 | 2000-02-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | | 主引用文献 | DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected
Nature, 403, 2000
|
|
3TEB
 | | endonuclease/exonuclease/phosphatase family protein from Leptotrichia buccalis C-1013-b | | 分子名称: | Endonuclease/exonuclease/phosphatase, MAGNESIUM ION | | 著者 | Chang, C, Bigelow, L, Muniez, I, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2011-08-12 | | 公開日 | 2011-08-31 | | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | | 主引用文献 | Crystal structure of endonuclease/exonuclease/phosphatase family protein from Leptotrichia buccalis C-1013-b
To be Published
|
|
8KA3
 | |
1DE9
 | | HUMAN APE1 ENDONUCLEASE WITH BOUND ABASIC DNA AND MN2+ ION | | 分子名称: | 5'-d(*CP*TP*AP*C)-3', 5'-d(*GP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-d(P*(3DR)P*GP*AP*TP*C)-3', ... | | 著者 | Mol, C.D, Izumi, T, Mitra, S, Tainer, J.A. | | 登録日 | 1999-11-13 | | 公開日 | 2000-02-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination
Nature, 403, 2000
|
|
3G3C
 | | Mth0212 (WT) in complex with a 6bp dsDNA containing a single one nucleotide long 3'-overhang | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 5'-D(*CP*GP*TP*AP*(UPS)P*TP*AP*CP*G)-3', 5'-D(*CP*GP*TP*AP*CP*TP*AP*CP*G)-3', ... | | 著者 | Lakomek, K, Dickmanns, A, Ficner, R. | | 登録日 | 2009-02-02 | | 公開日 | 2010-03-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.04 Å) | | 主引用文献 | Crystal Structure Analysis of DNA Uridine Endonuclease Mth212 Bound to DNA
J.Mol.Biol., 399, 2010
|
|
3G38
 | | The catalytically inactive mutant Mth0212 (D151N) in complex with an 8 bp dsDNA | | 分子名称: | 5'-D(*CP*CP*TP*GP*UP*GP*CP*GP*AP*T)-3', 5'-D(*CP*GP*CP*GP*CP*AP*GP*GP*C)-3', Exodeoxyribonuclease, ... | | 著者 | Lakomek, K, Dickmanns, A, Ficner, R. | | 登録日 | 2009-02-02 | | 公開日 | 2010-03-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.04 Å) | | 主引用文献 | Crystal Structure Analysis of DNA Uridine Endonuclease Mth212 Bound to DNA
J.Mol.Biol., 399, 2010
|
|
4B5H
 | | Substate bound inactive mutant of Neisseria AP endonuclease in presence of metal ions | | 分子名称: | 5'-D(*CP*GP*AP*TP*GP*GP*GP*TP*AP*GP*CP)-3', 5'-D(*GP*CP*TP*AP*CP*3DRP*CP*AP*TP*CP*GP)-3', MANGANESE (II) ION, ... | | 著者 | Lu, D, Silhan, J, MacDonald, J.T, Carpenter, E.P, Jensen, K, Tang, C.M, Baldwin, G.S, Freemont, P.S. | | 登録日 | 2012-08-03 | | 公開日 | 2012-10-17 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.05 Å) | | 主引用文献 | Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
Proc. Natl. Acad. Sci. U.S.A., 109, 2012
|
|
8J2F
 | | Human neutral shpingomyelinase | | 分子名称: | HEPTANE, MAGNESIUM ION, Sphingomyelin phosphodiesterase 2, ... | | 著者 | Zhang, S.S. | | 登録日 | 2023-04-14 | | 公開日 | 2023-12-06 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | | 主引用文献 | Molecular basis for the catalytic mechanism of human neutral sphingomyelinases 1 (hSMPD2).
Nat Commun, 14, 2023
|
|
5J3P
 | | Crystal structure of the catalytic domain of human tyrosyl DNA phosphodiesterase 2 | | 分子名称: | GLYCEROL, MAGNESIUM ION, Tyrosyl-DNA phosphodiesterase 2 | | 著者 | Hornyak, P, Pearl, L.H, Caldecott, K.W, Oliver, A.W. | | 登録日 | 2016-03-31 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2.
Biochem.J., 473, 2016
|
|
3G1K
 | |
6VX4
 | |
6O1K
 | | Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:2:2 complex (core complex) | | 分子名称: | Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq | | 著者 | Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. | | 登録日 | 2019-02-20 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Architectural principles for Hfq/Crc-mediated regulation of gene expression
Elife, 8, 2019
|
|
6O1M
 | | Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:4:2 complex | | 分子名称: | Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq | | 著者 | Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. | | 登録日 | 2019-02-20 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Architectural principles for Hfq/Crc-mediated regulation of gene expression.
Elife, 8, 2019
|
|
8UW3
 | | Human LINE-1 retrotransposon ORF2 protein engaged with template RNA in elongation state | | 分子名称: | Complementary DNA, LINE-1 retrotransposable element ORF2 protein, THYMIDINE-5'-TRIPHOSPHATE, ... | | 著者 | Thawani, A, Florez Ariza, A.J, Collins, K, Nogales, E. | | 登録日 | 2023-11-06 | | 公開日 | 2023-12-20 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Template and target-site recognition by human LINE-1 in retrotransposition.
Nature, 626, 2024
|
|
5INO
 | |
8SXT
 | | Structure of LINE-1 ORF2p with template:primer hybrid | | 分子名称: | DNA primer, LINE-1 retrotransposable element ORF2 protein, MAGNESIUM ION, ... | | 著者 | van Eeuwen, T, Taylor, M.S, Rout, M.P. | | 登録日 | 2023-05-24 | | 公開日 | 2024-01-10 | | 最終更新日 | 2024-02-14 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Structures, functions and adaptations of the human LINE-1 ORF2 protein.
Nature, 626, 2024
|
|
7AX1
 | |
3K55
 | | Structure of beta hairpin deletion mutant of beta toxin from Staphylococcus aureus | | 分子名称: | Beta-hemolysin, CHLORIDE ION, SODIUM ION | | 著者 | Kruse, A.C, Huseby, M, Shi, K, Digre, J, Ohlendorf, D.H, Earhart, C.A. | | 登録日 | 2009-10-06 | | 公開日 | 2011-01-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Structure of a mutant beta toxin from Staphylococcus aureus reveals domain swapping and conformational flexibility
Acta Crystallogr.,Sect.F, 67, 2011
|
|
6O1L
 | | Architectural principles for Hfq/Crc-mediated regulation of gene expression Hfq-Crc-amiE 2:3:2 complex | | 分子名称: | Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq | | 著者 | Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F. | | 登録日 | 2019-02-20 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | | 主引用文献 | Architectural principles for Hfq/Crc-mediated regulation of gene expression.
Elife, 8, 2019
|
|
7U50
 | |
5J3S
 | | Crystal structure of the catalytic domain of human tyrosyl DNA phosphodiesterase 2 in complex with a small molecule inhibitor | | 分子名称: | 2,4-dioxo-10-[3-(1H-tetrazol-5-yl)phenyl]-2,3,4,10-tetrahydropyrimido[4,5-b]quinoline-8-carbonitrile, Tyrosyl-DNA phosphodiesterase 2 | | 著者 | Hornyak, P, Pearl, L.H, Caldecott, K.W, Oliver, A.W. | | 登録日 | 2016-03-31 | | 公開日 | 2016-05-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2.
Biochem.J., 473, 2016
|
|
4B8C
 | | nuclease module of the yeast Ccr4-Not complex | | 分子名称: | GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1, GLUCOSE-REPRESSIBLE ALCOHOL DEHYDROGENASE TRANSCRIPTIONAL EFFECTOR, POLY(A) RIBONUCLEASE POP2 | | 著者 | Basquin, J, Conti, E. | | 登録日 | 2012-08-26 | | 公開日 | 2012-11-21 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.41 Å) | | 主引用文献 | Architecture of the Nuclease Module of the Yeast Ccr4-not Complex: The not1-Caf1-Ccr4 Interaction.
Mol.Cell, 48, 2012
|
|
