Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3I5V
DownloadVisualize
BU of 3i5v by Molmil
Crystal structure of beta toxin 275-280 from Staphylococcus aureus
分子名称: Beta-hemolysin, DIACYL GLYCEROL
著者Huseby, M, Shi, K, Kruse, A.C, Ohlendorf, D.H.
登録日2009-07-06
公開日2010-08-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure and biological functions of beta toxin from Staphylococcus aureus: Role of the hydrophobic beta hairpin in virulence
To be Published
1ATN
DownloadVisualize
BU of 1atn by Molmil
Atomic structure of the actin:DNASE I complex
分子名称: ACTIN, ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, ...
著者Kabsch, W, Mannherz, H.G, Suck, D, Pai, E, Holmes, K.C.
登録日1991-03-08
公開日1992-07-15
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Atomic structure of the actin:DNase I complex.
Nature, 347, 1990
7N94
DownloadVisualize
BU of 7n94 by Molmil
LINE-1 endonuclease domain complex with DNA
分子名称: DNA (5'-D(*AP*GP*CP*CP*CP*TP*TP*AP*AP*AP*AP*AP*GP*GP*AP*GP*CP*T)-3'), DNA (5'-D(*GP*CP*TP*CP*CP*TP*TP*TP*TP*TP*AP*AP*GP*GP*GP*CP*TP*A)-3'), LINE-1 retrotransposable element ORF2 protein
著者Korolev, S, Miller, I.
登録日2021-06-16
公開日2021-10-13
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural dissection of sequence recognition and catalytic mechanism of human LINE-1 endonuclease.
Nucleic Acids Res., 49, 2021
1DE8
DownloadVisualize
BU of 1de8 by Molmil
HUMAN APURINIC/APYRIMIDINIC ENDONUCLEASE-1 (APE1) BOUND TO ABASIC DNA
分子名称: DNA (5'-D(*CP*GP*AP*TP*CP*GP*GP*TP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*AP*CP*(3DR)P*GP*AP*TP*CP*G)-3'), MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE
著者Mol, C.D, Izumi, T, Mitra, S, Tainer, J.A.
登録日1999-11-13
公開日2000-02-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected
Nature, 403, 2000
3TEB
DownloadVisualize
BU of 3teb by Molmil
endonuclease/exonuclease/phosphatase family protein from Leptotrichia buccalis C-1013-b
分子名称: Endonuclease/exonuclease/phosphatase, MAGNESIUM ION
著者Chang, C, Bigelow, L, Muniez, I, Bearden, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2011-08-12
公開日2011-08-31
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献Crystal structure of endonuclease/exonuclease/phosphatase family protein from Leptotrichia buccalis C-1013-b
To be Published
8KA3
DownloadVisualize
BU of 8ka3 by Molmil
Arabidopsis AP endonuclease ARP complex with 22bp THF-containing DNA
分子名称: 1',2'-DIDEOXYRIBOFURANOSE-5'-PHOSPHATE, DNA (43-MER), DNA-(apurinic or apyrimidinic site) endonuclease, ...
著者Guo, W.T, Wu, B.X.
登録日2023-08-02
公開日2024-02-21
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into the catalytic mechanism of the AP endonuclease AtARP.
Structure, 2024
1DE9
DownloadVisualize
BU of 1de9 by Molmil
HUMAN APE1 ENDONUCLEASE WITH BOUND ABASIC DNA AND MN2+ ION
分子名称: 5'-d(*CP*TP*AP*C)-3', 5'-d(*GP*AP*TP*CP*GP*GP*TP*AP*G)-3', 5'-d(P*(3DR)P*GP*AP*TP*C)-3', ...
著者Mol, C.D, Izumi, T, Mitra, S, Tainer, J.A.
登録日1999-11-13
公開日2000-02-02
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination
Nature, 403, 2000
3G3C
DownloadVisualize
BU of 3g3c by Molmil
Mth0212 (WT) in complex with a 6bp dsDNA containing a single one nucleotide long 3'-overhang
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 5'-D(*CP*GP*TP*AP*(UPS)P*TP*AP*CP*G)-3', 5'-D(*CP*GP*TP*AP*CP*TP*AP*CP*G)-3', ...
著者Lakomek, K, Dickmanns, A, Ficner, R.
登録日2009-02-02
公開日2010-03-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Crystal Structure Analysis of DNA Uridine Endonuclease Mth212 Bound to DNA
J.Mol.Biol., 399, 2010
3G38
DownloadVisualize
BU of 3g38 by Molmil
The catalytically inactive mutant Mth0212 (D151N) in complex with an 8 bp dsDNA
分子名称: 5'-D(*CP*CP*TP*GP*UP*GP*CP*GP*AP*T)-3', 5'-D(*CP*GP*CP*GP*CP*AP*GP*GP*C)-3', Exodeoxyribonuclease, ...
著者Lakomek, K, Dickmanns, A, Ficner, R.
登録日2009-02-02
公開日2010-03-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Crystal Structure Analysis of DNA Uridine Endonuclease Mth212 Bound to DNA
J.Mol.Biol., 399, 2010
4B5H
DownloadVisualize
BU of 4b5h by Molmil
Substate bound inactive mutant of Neisseria AP endonuclease in presence of metal ions
分子名称: 5'-D(*CP*GP*AP*TP*GP*GP*GP*TP*AP*GP*CP)-3', 5'-D(*GP*CP*TP*AP*CP*3DRP*CP*AP*TP*CP*GP)-3', MANGANESE (II) ION, ...
著者Lu, D, Silhan, J, MacDonald, J.T, Carpenter, E.P, Jensen, K, Tang, C.M, Baldwin, G.S, Freemont, P.S.
登録日2012-08-03
公開日2012-10-17
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural basis for the recognition and cleavage of abasic DNA in Neisseria meningitidis.
Proc. Natl. Acad. Sci. U.S.A., 109, 2012
8J2F
DownloadVisualize
BU of 8j2f by Molmil
Human neutral shpingomyelinase
分子名称: HEPTANE, MAGNESIUM ION, Sphingomyelin phosphodiesterase 2, ...
著者Zhang, S.S.
登録日2023-04-14
公開日2023-12-06
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.07 Å)
主引用文献Molecular basis for the catalytic mechanism of human neutral sphingomyelinases 1 (hSMPD2).
Nat Commun, 14, 2023
5J3P
DownloadVisualize
BU of 5j3p by Molmil
Crystal structure of the catalytic domain of human tyrosyl DNA phosphodiesterase 2
分子名称: GLYCEROL, MAGNESIUM ION, Tyrosyl-DNA phosphodiesterase 2
著者Hornyak, P, Pearl, L.H, Caldecott, K.W, Oliver, A.W.
登録日2016-03-31
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2.
Biochem.J., 473, 2016
3G1K
DownloadVisualize
BU of 3g1k by Molmil
Mth0212 (WT) crystallized in a monoclinic space group
分子名称: Exodeoxyribonuclease, MAGNESIUM ION
著者Lakomek, K, Dickmanns, A, Ficner, R.
登録日2009-01-30
公開日2010-03-09
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure Analysis of DNA Uridine Endonuclease Mth212 Bound to DNA
J.Mol.Biol., 399, 2010
6VX4
DownloadVisualize
BU of 6vx4 by Molmil
Density-fitted Model Structure of Antibody Variable Domains of TyTx11 in Complex with Typhoid Toxin
分子名称: Cytolethal distending toxin subunit B, Pertussis like toxin subunit B, Pertussis toxin-like subunit ArtA, ...
著者Nguyen, T, Song, J.
登録日2020-02-21
公開日2021-02-24
最終更新日2021-07-14
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Mechanisms of typhoid toxin neutralization by antibodies targeting glycan receptor binding and nuclease subunits.
Iscience, 24, 2021
6O1K
DownloadVisualize
BU of 6o1k by Molmil
Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:2:2 complex (core complex)
分子名称: Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq
著者Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F.
登録日2019-02-20
公開日2019-03-13
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Architectural principles for Hfq/Crc-mediated regulation of gene expression
Elife, 8, 2019
6O1M
DownloadVisualize
BU of 6o1m by Molmil
Architectural principles for Hfq/Crc-mediated regulation of gene expression. Hfq-Crc-amiE 2:4:2 complex
分子名称: Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq
著者Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F.
登録日2019-02-20
公開日2019-03-13
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.15 Å)
主引用文献Architectural principles for Hfq/Crc-mediated regulation of gene expression.
Elife, 8, 2019
8UW3
DownloadVisualize
BU of 8uw3 by Molmil
Human LINE-1 retrotransposon ORF2 protein engaged with template RNA in elongation state
分子名称: Complementary DNA, LINE-1 retrotransposable element ORF2 protein, THYMIDINE-5'-TRIPHOSPHATE, ...
著者Thawani, A, Florez Ariza, A.J, Collins, K, Nogales, E.
登録日2023-11-06
公開日2023-12-20
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Template and target-site recognition by human LINE-1 in retrotransposition.
Nature, 626, 2024
5INO
DownloadVisualize
BU of 5ino by Molmil
Human Tdp2 reaction product (5'-phosphorylated DNA)-Mg2+ complex
分子名称: DNA (5'-D(P*CP*CP*GP*AP*AP*TP*TP*CP*G)-3'), SULFATE ION, Tyrosyl-DNA phosphodiesterase 2
著者Schellenberg, M.J, Williams, R.S.
登録日2016-03-07
公開日2016-04-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.205 Å)
主引用文献Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Nucleic Acids Res., 44, 2016
8SXT
DownloadVisualize
BU of 8sxt by Molmil
Structure of LINE-1 ORF2p with template:primer hybrid
分子名称: DNA primer, LINE-1 retrotransposable element ORF2 protein, MAGNESIUM ION, ...
著者van Eeuwen, T, Taylor, M.S, Rout, M.P.
登録日2023-05-24
公開日2024-01-10
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structures, functions and adaptations of the human LINE-1 ORF2 protein.
Nature, 626, 2024
7AX1
DownloadVisualize
BU of 7ax1 by Molmil
Crystal structure of the human CCR4-CAF1 complex
分子名称: CCR4-NOT transcription complex subunit 6, CCR4-NOT transcription complex subunit 7, MAGNESIUM ION
著者Chen, Y, Khazina, E, Weichenrieder, O.
登録日2020-11-09
公開日2021-05-12
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal structure and functional properties of the human CCR4-CAF1 deadenylase complex.
Nucleic Acids Res., 49, 2021
3K55
DownloadVisualize
BU of 3k55 by Molmil
Structure of beta hairpin deletion mutant of beta toxin from Staphylococcus aureus
分子名称: Beta-hemolysin, CHLORIDE ION, SODIUM ION
著者Kruse, A.C, Huseby, M, Shi, K, Digre, J, Ohlendorf, D.H, Earhart, C.A.
登録日2009-10-06
公開日2011-01-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Structure of a mutant beta toxin from Staphylococcus aureus reveals domain swapping and conformational flexibility
Acta Crystallogr.,Sect.F, 67, 2011
6O1L
DownloadVisualize
BU of 6o1l by Molmil
Architectural principles for Hfq/Crc-mediated regulation of gene expression Hfq-Crc-amiE 2:3:2 complex
分子名称: Catabolite repression control protein, RNA (5'-R(*AP*AP*AP*AP*AP*UP*AP*AP*CP*AP*AP*CP*AP*AP*GP*AP*GP*G)-3'), RNA-binding protein Hfq
著者Pei, X.Y, Dendooven, T, Sonnleitner, E, Chen, S, Blasi, U, Luisi, B.F.
登録日2019-02-20
公開日2019-03-13
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.37 Å)
主引用文献Architectural principles for Hfq/Crc-mediated regulation of gene expression.
Elife, 8, 2019
7U50
DownloadVisualize
BU of 7u50 by Molmil
APE1 bound to a nucleosome core particle with AP-site at SHL-6
分子名称: DNA (144-MER), DNA (145-MER), DNA-(apurinic or apyrimidinic site) endonuclease, ...
著者Weaver, T.M, Freudenthal, B.D.
登録日2022-03-01
公開日2022-09-07
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for APE1 processing DNA damage in the nucleosome.
Nat Commun, 13, 2022
5J3S
DownloadVisualize
BU of 5j3s by Molmil
Crystal structure of the catalytic domain of human tyrosyl DNA phosphodiesterase 2 in complex with a small molecule inhibitor
分子名称: 2,4-dioxo-10-[3-(1H-tetrazol-5-yl)phenyl]-2,3,4,10-tetrahydropyrimido[4,5-b]quinoline-8-carbonitrile, Tyrosyl-DNA phosphodiesterase 2
著者Hornyak, P, Pearl, L.H, Caldecott, K.W, Oliver, A.W.
登録日2016-03-31
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Mode of action of DNA-competitive small molecule inhibitors of tyrosyl DNA phosphodiesterase 2.
Biochem.J., 473, 2016
4B8C
DownloadVisualize
BU of 4b8c by Molmil
nuclease module of the yeast Ccr4-Not complex
分子名称: GENERAL NEGATIVE REGULATOR OF TRANSCRIPTION SUBUNIT 1, GLUCOSE-REPRESSIBLE ALCOHOL DEHYDROGENASE TRANSCRIPTIONAL EFFECTOR, POLY(A) RIBONUCLEASE POP2
著者Basquin, J, Conti, E.
登録日2012-08-26
公開日2012-11-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献Architecture of the Nuclease Module of the Yeast Ccr4-not Complex: The not1-Caf1-Ccr4 Interaction.
Mol.Cell, 48, 2012

221051

件を2024-06-12に公開中

PDB statisticsPDBj update infoContact PDBjnumon