7N94
LINE-1 endonuclease domain complex with DNA
Summary for 7N94
Entry DOI | 10.2210/pdb7n94/pdb |
Descriptor | LINE-1 retrotransposable element ORF2 protein, DNA (5'-D(*GP*CP*TP*CP*CP*TP*TP*TP*TP*TP*AP*AP*GP*GP*GP*CP*TP*A)-3'), DNA (5'-D(*AP*GP*CP*CP*CP*TP*TP*AP*AP*AP*AP*AP*GP*GP*AP*GP*CP*T)-3') (3 entities in total) |
Functional Keywords | endonuclease, non-ltr retrotransposon, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 76208.84 |
Authors | Korolev, S.,Miller, I. (deposition date: 2021-06-16, release date: 2021-10-13, Last modification date: 2023-10-18) |
Primary citation | Miller, I.,Totrov, M.,Korotchkina, L.,Kazyulkin, D.N.,Gudkov, A.V.,Korolev, S. Structural dissection of sequence recognition and catalytic mechanism of human LINE-1 endonuclease. Nucleic Acids Res., 49:11350-11366, 2021 Cited by PubMed: 34554261DOI: 10.1093/nar/gkab826 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.85 Å) |
Structure validation
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