4Y0U
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![BU of 4y0u by Molmil](/molmil-images/mine/4y0u) | Crystal Structure of 6Alpha-Hydroxymethylpenicillanate Complexed with OXA-58, a Carbapenem hydrolyzing Class D betalactamase from Acinetobacter baumanii. | 分子名称: | 2-(1-CARBOXY-2-HYDROXY-ETHYL)-5,5-DIMETHYL-THIAZOLIDINE-4-CARBOXYLIC ACID, Beta-lactamase | 著者 | Pratap, S, Katiki, M, Gill, P, Golemi-Kotra, D, Kumar, P. | 登録日 | 2015-02-06 | 公開日 | 2016-01-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Active-Site Plasticity Is Essential to Carbapenem Hydrolysis by OXA-58 Class D beta-Lactamase of Acinetobacter baumannii. Antimicrob.Agents Chemother., 60, 2015
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4Y0O
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![BU of 4y0o by Molmil](/molmil-images/mine/4y0o) | Crystal structure of OXA-58, a carbapenem hydrolyzing Class D beta-lactamase from Acinetobacter baumanii. | 分子名称: | Beta-lactamase | 著者 | Pratap, S, Katiki, M, Gill, P, Golemi-Kotra, D, Kumar, P. | 登録日 | 2015-02-06 | 公開日 | 2016-01-13 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | Active-Site Plasticity Is Essential to Carbapenem Hydrolysis by OXA-58 Class D beta-Lactamase of Acinetobacter baumannii. Antimicrob.Agents Chemother., 60, 2015
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4YIN
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![BU of 4yin by Molmil](/molmil-images/mine/4yin) | Crystal structure of the extended-spectrum beta-lactamase OXA-145 | 分子名称: | Beta-lactamase, CITRATE ANION | 著者 | Meziane-Cherif, D, Bonnet, R, Haouz, A, Courvalin, P. | 登録日 | 2015-03-02 | 公開日 | 2016-02-10 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structural insights into the loss of penicillinase and the gain of ceftazidimase activities by OXA-145 beta-lactamase in Pseudomonas aeruginosa. J. Antimicrob. Chemother., 71, 2016
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1M6K
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![BU of 1m6k by Molmil](/molmil-images/mine/1m6k) | Structure of the OXA-1 class D beta-lactamase | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, beta-lactamase OXA-1 | 著者 | Sun, T, Nukaga, M, Mayama, K, Braswell, E.H, Knox, J.R. | 登録日 | 2002-07-16 | 公開日 | 2003-01-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Comparison of beta-lactamases of classes A and D: 1.5A crystallographic structure of the class D OXA-1 oxacillinase PROTEIN SCI., 12, 2003
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7K5V
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![BU of 7k5v by Molmil](/molmil-images/mine/7k5v) | OXA-48 bound by Compound 3.1 | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase, CHLORIDE ION, ... | 著者 | Taylor, D.M, Hu, L, Prasad, B.V.V, Palzkill, T. | 登録日 | 2020-09-17 | 公開日 | 2021-12-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of Escherichia coli Producing OXA-48. Acs Infect Dis., 7, 2021
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7JHQ
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![BU of 7jhq by Molmil](/molmil-images/mine/7jhq) | OXA-48 bound by Compound 2.3 | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase OXA-48, CHLORIDE ION, ... | 著者 | Taylor, D.M, Hu, L, Prasad, B.V.V, Palzkill, T. | 登録日 | 2020-07-21 | 公開日 | 2021-12-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of Escherichia coli Producing OXA-48. Acs Infect Dis., 7, 2021
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6MPQ
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![BU of 6mpq by Molmil](/molmil-images/mine/6mpq) | 1.95 Ang crystal structure of OXA-24/40 beta-lactamase in complex the inhibitor ETX2514 | 分子名称: | (2S,5R)-1-formyl-3-methyl-5-[(sulfooxy)amino]-1,2,5,6-tetrahydropyridine-2-carboxamide, Beta-lactamase, CHLORIDE ION | 著者 | van den Akker, F, Kumar, V. | 登録日 | 2018-10-08 | 公開日 | 2019-02-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Targeting Multidrug-ResistantAcinetobacterspp.: Sulbactam and the Diazabicyclooctenone beta-Lactamase Inhibitor ETX2514 as a Novel Therapeutic Agent. MBio, 10, 2019
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6N6W
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![BU of 6n6w by Molmil](/molmil-images/mine/6n6w) | |
2ZC6
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![BU of 2zc6 by Molmil](/molmil-images/mine/2zc6) | Penicillin-binding protein 1A (PBP 1A) acyl-enzyme complex (tebipenem) from Streptococcus pneumoniae | 分子名称: | (4R,5S)-3-(1-(4,5-dihydrothiazol-2-yl)azetidin-3-ylthio)-5-((2S,3R)-3-hydroxy-1-oxobutan-2-yl)-4-methyl-4,5- dihydro-1H-pyrrole-2-carboxylic acid, Penicillin-binding protein 1A, ZINC ION | 著者 | Yamada, M, Watanabe, T, Takeuchi, Y. | 登録日 | 2007-11-02 | 公開日 | 2008-04-08 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structures of Biapenem and Tebipenem Complexed with Penicillin-Binding Proteins 2X and 1A from Streptococcus pneumoniae Antimicrob.Agents Chemother., 52, 2008
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6N6V
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![BU of 6n6v by Molmil](/molmil-images/mine/6n6v) | |
6N1N
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![BU of 6n1n by Molmil](/molmil-images/mine/6n1n) | Crystal structure of class D beta-lactamase from Sebaldella termitidis ATCC 33386 | 分子名称: | Beta-lactamase, GLYCEROL, SULFATE ION | 著者 | Michalska, K, Tesar, C, Endres, M, Joachimiak, A, Satchell, K.J, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-11-09 | 公開日 | 2018-12-19 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | 主引用文献 | Crystal structure of class D beta-lactamase from Sebaldella termitidis ATCC 33386 To Be Published
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6N6T
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![BU of 6n6t by Molmil](/molmil-images/mine/6n6t) | OXA-23 mutant F110A/M221A low pH form | 分子名称: | Beta-lactamase oxa23, CITRATE ANION | 著者 | Smith, C.A, Vakulenko, S.B. | 登録日 | 2018-11-27 | 公開日 | 2018-12-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases. Antimicrob. Agents Chemother., 63, 2019
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6N6U
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![BU of 6n6u by Molmil](/molmil-images/mine/6n6u) | |
6N6X
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![BU of 6n6x by Molmil](/molmil-images/mine/6n6x) | |
6NLW
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![BU of 6nlw by Molmil](/molmil-images/mine/6nlw) | The crystal structure of class D carbapenem-hydrolyzing beta-lactamase BlaA from Shewanella oneidensis MR-1 | 分子名称: | Beta-lactamase, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Tan, K, Tesar, C, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2019-01-09 | 公開日 | 2019-01-23 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | The crystal structure of class D carbapenem-hydrolyzing beta-lactamase BlaA from Shewanella oneidensis MR-1 To Be Published
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6N6Y
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![BU of 6n6y by Molmil](/molmil-images/mine/6n6y) | |
7L8O
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![BU of 7l8o by Molmil](/molmil-images/mine/7l8o) | OXA-48 bound by Compound 4.3 | 分子名称: | 1,2-ETHANEDIOL, 9H-fluorene-2,7-disulfonate, Beta-lactamase, ... | 著者 | Taylor, D.M, Hu, L, Prasad, B.V.V, Palzkill, T. | 登録日 | 2020-12-31 | 公開日 | 2021-12-01 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of Escherichia coli Producing OXA-48. Acs Infect Dis., 7, 2021
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7L5V
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![BU of 7l5v by Molmil](/molmil-images/mine/7l5v) | Crystal Structure of the Class D Beta-lactamase OXA-935 from Pseudomonas aeruginosa, Monoclinic Crystal Form | 分子名称: | Beta-lactamase | 著者 | Minasov, G, Shuvalova, L, Rosas-Lemus, M, Brunzelle, J.S, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-12-23 | 公開日 | 2021-12-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Functional and Structural Characterization of OXA-935, a Novel OXA-10-Family beta-Lactamase from Pseudomonas aeruginosa. Antimicrob.Agents Chemother., 66, 2022
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7L5T
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![BU of 7l5t by Molmil](/molmil-images/mine/7l5t) | Crystal Structure of the Oxacillin-hydrolyzing Class D Extended-spectrum Beta-lactamase OXA-14 from Pseudomonas aeruginosa in Complex with Covalently Bound Clavulanic Acid | 分子名称: | (2E)-3-[(4-hydroxy-2-oxobutyl)amino]prop-2-enal, Beta-lactamase, CHLORIDE ION, ... | 著者 | Minasov, G, Shuvalova, L, Rosas-Lemus, M, Brunzelle, J.S, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID), Center for Membrane Proteins of Infectious Diseases (MPID) | 登録日 | 2020-12-22 | 公開日 | 2021-12-29 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Crystal Structure of the Oxacillin-hydrolyzing Class D Extended-spectrum Beta-lactamase OXA-14 from Pseudomonas aeruginosa in Complex with Covalently Bound Clavulanic Acid To Be Published
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6NHU
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![BU of 6nhu by Molmil](/molmil-images/mine/6nhu) | Crystal Structure of the Beta Lactamase Class D YbxI from Agrobacterium fabrum | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase, GLYCEROL, ... | 著者 | Kim, Y, Welk, L, Endres, M, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-12-23 | 公開日 | 2019-01-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structure of the Beta Lactamase Class D YbxI from Agrobacterium fabrum To Be Published
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6NHS
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![BU of 6nhs by Molmil](/molmil-images/mine/6nhs) | Crystal Structure of the Beta Lactamase Class D YbXI from Nostoc | 分子名称: | 1,2-ETHANEDIOL, Beta-lactamase, CHLORIDE ION, ... | 著者 | Kim, Y, Tesar, C, Endres, M, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2018-12-23 | 公開日 | 2019-01-16 | 最終更新日 | 2019-12-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of the Beta Lactamase Class D YbXI from Nostoc To Be Published
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7L5R
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![BU of 7l5r by Molmil](/molmil-images/mine/7l5r) | Crystal Structure of the Oxacillin-hydrolyzing Class D Extended-spectrum Beta-lactamase OXA-14 from Pseudomonas aeruginosa | 分子名称: | Beta-lactamase, GLYCEROL, SULFATE ION | 著者 | Minasov, G, Shuvalova, L, Rosas-Lemus, M, Brunzelle, J.S, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2020-12-22 | 公開日 | 2021-12-29 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Functional and Structural Characterization of OXA-935, a Novel OXA-10-Family beta-Lactamase from Pseudomonas aeruginosa. Antimicrob.Agents Chemother., 66, 2022
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7KHY
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![BU of 7khy by Molmil](/molmil-images/mine/7khy) | Crystal structure of OXA-163 K73A in complex with meropenem | 分子名称: | (4R,5S)-3-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-5-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-4-methyl-4,5-d ihydro-1H-pyrrole-2-carboxylic acid, (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-lactamase, ... | 著者 | Palzkill, T, Hu, L, Sankaran, B, Prasad, B.V.V. | 登録日 | 2020-10-22 | 公開日 | 2021-02-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Mechanistic Basis of OXA-48-like beta-Lactamases' Hydrolysis of Carbapenems. Acs Infect Dis., 7, 2021
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7KH9
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![BU of 7kh9 by Molmil](/molmil-images/mine/7kh9) | Crystal structure of OXA-48 K73A in complex with imipenem | 分子名称: | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, Beta-lactamase, CHLORIDE ION | 著者 | Palzkill, T, Hu, L, Sankaran, B, Prasad, B.V.V. | 登録日 | 2020-10-20 | 公開日 | 2021-02-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Mechanistic Basis of OXA-48-like beta-Lactamases' Hydrolysis of Carbapenems. Acs Infect Dis., 7, 2021
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7KHZ
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![BU of 7khz by Molmil](/molmil-images/mine/7khz) | Crystal structure of OXA-163 K73A in complex with imipenem | 分子名称: | (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid, Beta-lactamase, CHLORIDE ION, ... | 著者 | Palzkill, T, Hu, L, Sankaran, B, Prasad, B.V.V. | 登録日 | 2020-10-22 | 公開日 | 2021-02-10 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | Mechanistic Basis of OXA-48-like beta-Lactamases' Hydrolysis of Carbapenems. Acs Infect Dis., 7, 2021
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