4YIN

Crystal structure of the extended-spectrum beta-lactamase OXA-145

Summary for 4YIN

Entry DOI	10.2210/pdb4yin/pdb
Descriptor	Beta-lactamase, CITRATE ANION (3 entities in total)
Functional Keywords	antibiotic resistance, extended-spectrum beta-lactamase, class d, oxacillinase, hydrolase
Biological source	Pseudomonas aeruginosa
Total number of polymer chains	2
Total formula weight	55106.45
Authors	Meziane-Cherif, D.,Bonnet, R.,Haouz, A.,Courvalin, P. (deposition date: 2015-03-02, release date: 2016-02-10, Last modification date: 2018-04-18)
Primary citation	Meziane-Cherif, D.,Bonnet, R.,Haouz, A.,Courvalin, P. Structural insights into the loss of penicillinase and the gain of ceftazidimase activities by OXA-145 beta-lactamase in Pseudomonas aeruginosa. J. Antimicrob. Chemother., 71:395-402, 2016 Cited by PubMed: 26568564 DOI: 10.1093/jac/dkv375 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation