6N6Y
OXA-23 mutant F110A/M221A neutral pH form meropenem complex
Summary for 6N6Y
| Entry DOI | 10.2210/pdb6n6y/pdb |
| Descriptor | Beta-lactamase oxa23, meropenem, bound form (2 entities in total) |
| Functional Keywords | carbapenemase, antibiotic resistance, mutant, hydrolase |
| Biological source | Acinetobacter baumannii |
| Total number of polymer chains | 1 |
| Total formula weight | 27470.65 |
| Authors | Smith, C.A.,Vakulenko, S.B. (deposition date: 2018-11-27, release date: 2018-12-19, Last modification date: 2023-11-15) |
| Primary citation | Stewart, N.K.,Smith, C.A.,Antunes, N.T.,Toth, M.,Vakulenko, S.B. Role of the Hydrophobic Bridge in the Carbapenemase Activity of Class D beta-Lactamases. Antimicrob. Agents Chemother., 63:-, 2019 Cited by PubMed: 30530607DOI: 10.1128/AAC.02191-18 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.501 Å) |
Structure validation
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