PDB: 301 件ウェブページステータス検索Chemie searchBIRD

---

6OZ4	Crystal structure of broadly neutralizing antibody N49P6 Fab in complex with HIV-1 BG505 SOSIP.664 Env trimer ectodomain. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... 著者 Tolbert, W.D, Pazgier, M. 登録日 2019-05-15 公開日 2020-08-19 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.05 Å) 主引用文献 Near-Pan-neutralizing, Plasma Deconvoluted Antibody N49P6 Mimics Host Receptor CD4 in Its Quaternary Interactions with the HIV-1 Envelope Trimer. Mbio, 2021
6OZC	BG505 SOSIP.664 with 2G12 Fab2 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2G12 Fab Heavy chain, ... 著者 Cottrell, C.A, Ward, A.B. 登録日 2019-05-15 公開日 2020-05-20 最終更新日 2020-08-19 実験手法 ELECTRON MICROSCOPY (3.79 Å) 主引用文献 Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions. Structure, 28, 2020
6OT1	Cryo-EM structure of vaccine-elicited antibody 0PV-b.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122 分子名称: 0PV-b.01 heavy, 0PV-b.01 light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gorman, J, Kwong, P.D. 登録日 2019-05-02 公開日 2019-08-07 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
6OSY	Cryo-EM structure of vaccine-elicited antibody 0PV-a.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122 分子名称: 0PV-a.01 Heavy, 0PV-a.01 Light, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gorman, J, Kwong, P.D. 登録日 2019-05-02 公開日 2019-07-24 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.3 Å) 主引用文献 Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
6ORO	Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab874NHP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab874NHP antibody Fab heavy chain, ... 著者 Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. 登録日 2019-04-30 公開日 2019-06-12 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
6ORQ	Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab275MUR 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab275MUR antibody Fab heavy chain, ... 著者 Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. 登録日 2019-04-30 公開日 2019-06-12 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
6ORN	Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch bNAb 10-1074 分子名称: 10-1074 antibody Fab heavy chain, 10-1074 antibody Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. 登録日 2019-04-30 公開日 2019-06-12 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.05 Å) 主引用文献 Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
6ORP	Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab897NHP 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab897NHP antibody Fab heavy chain, ... 著者 Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. 登録日 2019-04-30 公開日 2019-06-12 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques. Nature, 570, 2019
6OPN	CD4- and 17-bound HIV-1 Env B41 SOSIP in complex with small molecule GO35 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... 著者 Ozorowski, G, Torres, J.L, Ward, A.B. 登録日 2019-04-25 公開日 2020-10-21 最終更新日 2020-12-09 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33, 2020
6OPP	Asymmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with DDM 分子名称: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Ozorowski, G, Torres, J.L, Ward, A.B. 登録日 2019-04-25 公開日 2020-10-21 最終更新日 2020-12-09 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33, 2020
6OPO	Symmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with DDM 分子名称: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Ozorowski, G, Torres, J.L, Ward, A.B. 登録日 2019-04-25 公開日 2020-10-21 最終更新日 2020-12-09 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33, 2020
6OPQ	CD4- and 17-bound HIV-1 Env B41 SOSIP frozen with LMNG 分子名称: 17b Fab heavy chain, 17b Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Ozorowski, G, Torres, J.L, Ward, A.B. 登録日 2019-04-25 公開日 2020-10-21 最終更新日 2020-12-09 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33, 2020
6OPA	Crystal structure of bovine Fab NC-Cow1 in complex with HIV-1 BG505 SOSIP.664, and human Fabs 35022 and PGT128 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp160, ... 著者 Stanfield, R.L, Wilson, I.A. 登録日 2019-04-24 公開日 2020-04-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (4.084 Å) 主引用文献 Structural basis of broad HIV neutralization by a vaccine-induced cow antibody. Sci Adv, 6, 2020
6OKP	B41 SOSIP.664 in complex with the silent-face antibody SF12 and V3-targeting antibody 10-1074 分子名称: 10-1074 Heavy Chain,10-1074 Heavy Chain, 10-1074 Light Chain,10-1074 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Barnes, C.O, Bjorkman, P.J. 登録日 2019-04-14 公開日 2019-06-05 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.28 Å) 主引用文献 Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope. Immunity, 50, 2019
6OHY	Chimpanzee SIV Env trimeric ectodomain. 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Pallesen, J, Andrabi, R, de Val, N, Burton, D.R, Ward, A.B. 登録日 2019-04-08 公開日 2019-06-05 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template. Cell Rep, 27, 2019
6R2G	Crystal structure of a single-chain protein mimetic of the gp41 NHR trimer in complex with the synthetic CHR peptide C34 分子名称: Envelope glycoprotein gp160, PHOSPHATE ION, Single-chain protein mimetics of the N-terminal heptad-repeat region of gp41 著者 Camara-Artigas, A, Conejero-Lara, F, Jurado, S, Cano-Munoz, M, Morel, B. 登録日 2019-03-17 公開日 2019-07-10 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and Thermodynamic Analysis of HIV-1 Fusion Inhibition Using Small gp41 Mimetic Proteins. J.Mol.Biol., 431, 2019
6NQD	Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer in complex with 8ANC195 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 8ANC195 G52K5 heavy chain, ... 著者 Fang, Q, Rossmann, M.G. 登録日 2019-01-21 公開日 2019-03-06 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 A sequestered fusion peptide in the structure of an HIV-1 transmitted founder envelope trimer. Nat Commun, 10, 2019
6NNJ	Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to CH31 scFv in Complex with Crystallization Chaperones 3H109L Fab and 35O22 scFv at 3.1 Angstrom 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain, ... 著者 Lai, Y.-T, Kwong, P.D. 登録日 2019-01-15 公開日 2019-02-27 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Improvement of antibody functionality by structure-guided paratope engraftment. Nat Commun, 10, 2019
6NNF	Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to VRC01 FR3-03 scFv in Complex with Crystallization Chaperones 3H109L Fab and 35O22 scFv at 3.5 Angstrom 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain, ... 著者 Lai, Y.-T, Kwong, P.D. 登録日 2019-01-14 公開日 2019-02-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.762 Å) 主引用文献 Improvement of antibody functionality by structure-guided paratope engraftment. Nat Commun, 10, 2019
6NM6	Crystal Structure of HIV-1 BG505 SOSIP.664 Prefusion Env Trimer Bound to N6 FR3-03 scFv in Complex with Crystallization Chaperones 3H109L Fab and 35O22 scFv at 3.2 Angstrom 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv heavy chain, ... 著者 Lai, Y.-T, Kwong, P.D. 登録日 2019-01-10 公開日 2019-02-27 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.739 Å) 主引用文献 Improvement of antibody functionality by structure-guided paratope engraftment. Nat Commun, 10, 2019
6NFC	BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP42 fragmentantigen binding and base-binding RM20A3 fragment antigen binding 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG18-like precursor HMP42 fragment antigen binding heavy chain, ... 著者 Ozorowski, G, Torres, J.L, Ward, A.B. 登録日 2018-12-19 公開日 2019-11-06 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.43 Å) 主引用文献 A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science, 366, 2019
6NF2	Cryo-EM structure of vaccine-elicited antibody 0PV-c.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122 分子名称: 0PV-c.01 Heavy Chain, 0PV-c.01 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Gorman, J, Kwong, P.D. 登録日 2018-12-18 公開日 2019-07-24 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization. Cell, 178, 2019
6NF5	BG505 MD64 N332-GT5 SOSIP trimer in complex with BG18-like precursor HMP1 fragmentantigen binding and base-binding RM20A3 fragment antigen binding 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG18-like precursor HMP1 fragment antigen binding heavy chain, ... 著者 Ozorowski, G, Torres, J.L, Steichen, J.M, Schief, W.R, Ward, A.B. 登録日 2018-12-18 公開日 2019-11-06 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.71 Å) 主引用文献 A generalized HIV vaccine design strategy for priming of broadly neutralizing antibody responses. Science, 366, 2019
6NC2	AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody ACS202 fragment antigen binding 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC011 v4.2 SOSIP gp120, ... 著者 Cottrell, C.A, Ozorowski, G, Yuan, M, Copps, J, Wilson, I.A, Ward, A.B. 登録日 2018-12-10 公開日 2019-06-19 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (5.2 Å) 主引用文献 Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host Microbe, 25, 2019
6NC3	AMC011 v4.2 SOSIP Env trimer in complex with fusion peptide targeting antibody VRC34 fragment antigen binding 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Env AMC011 v4.2 SOSIP gp120, ... 著者 Cottrell, C.A, Ozorowski, G, Torres, J.L, Ward, A.B. 登録日 2018-12-10 公開日 2019-06-19 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies. Cell Host Microbe, 25, 2019

<12345678910111213>