6OPN

CD4- and 17-bound HIV-1 Env B41 SOSIP in complex with small molecule GO35

Summary for 6OPN

Entry DOI	10.2210/pdb6opn/pdb
EMDB information	20150
Descriptor	Envelope glycoprotein gp160, Envelope glycoprotein gp41, T-cell surface glycoprotein CD4, ... (7 entities in total)
Functional Keywords	hiv-1, env, cd4, receptor-bound state, small molecule, fusion inhibitor, viral protein, viral protein-immune system complex, viral protein/immune system
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	9
Total formula weight	308830.21
Authors	Ozorowski, G.,Torres, J.L.,Ward, A.B. (deposition date: 2019-04-25, release date: 2020-10-21, Last modification date: 2020-12-09)
Primary citation	Ozorowski, G.,Torres, J.L.,Santos-Martins, D.,Forli, S.,Ward, A.B. A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide. Cell Rep, 33:108428-108428, 2020 Cited by PubMed: 33238117 DOI: 10.1016/j.celrep.2020.108428 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.5 Å)

Structure validation