6OPP

Asymmetric model of CD4- and 17-bound B41 HIV-1 Env SOSIP in complex with DDM

Summary for 6OPP

• Entry DOI: 10.2210/pdb6opp/pdb
• EMDB information: 20152
• Descriptor: 17b Fab light chain, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (13 entities in total)
• Functional Keywords: hiv-1, env, cd4, receptor-bound state, detergent, ddm, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 15
• Total formula weight: 467575.24

Authors

Ozorowski, G.,Torres, J.L.,Ward, A.B. (deposition date: 2019-04-25, release date: 2020-10-21, Last modification date: 2020-12-09)

• Primary citation: Ozorowski, G.,Torres, J.L.,Santos-Martins, D.,Forli, S.,Ward, A.B.; A Strain-Specific Inhibitor of Receptor-Bound HIV-1 Targets a Pocket near the Fusion Peptide.; Cell Rep, 33:108428-108428, 2020; PubMed: 33238117; DOI: 10.1016/j.celrep.2020.108428

Experimental method

ELECTRON MICROSCOPY (3.7 Å)