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6OPA

Crystal structure of bovine Fab NC-Cow1 in complex with HIV-1 BG505 SOSIP.664, and human Fabs 35022 and PGT128

Summary for 6OPA
Entry DOI10.2210/pdb6opa/pdb
DescriptorEnvelope glycoprotein gp160, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (15 entities in total)
Functional Keywordshiv-1 broadly neutralizing antibody, viral protein-immune system complex, immune system
Biological sourceHuman immunodeficiency virus 1
More
Total number of polymer chains8
Total formula weight229340.44
Authors
Stanfield, R.L.,Wilson, I.A. (deposition date: 2019-04-24, release date: 2020-04-01, Last modification date: 2023-10-11)
Primary citationStanfield, R.L.,Berndsen, Z.T.,Huang, R.,Sok, D.,Warner, G.,Torres, J.L.,Burton, D.R.,Ward, A.B.,Wilson, I.A.,Smider, V.V.
Structural basis of broad HIV neutralization by a vaccine-induced cow antibody.
Sci Adv, 6:eaba0468-eaba0468, 2020
Cited by
PubMed: 32518821
DOI: 10.1126/sciadv.aba0468
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (4.084 Å)
Structure validation

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