6OPA
Crystal structure of bovine Fab NC-Cow1 in complex with HIV-1 BG505 SOSIP.664, and human Fabs 35022 and PGT128
Summary for 6OPA
Entry DOI | 10.2210/pdb6opa/pdb |
Descriptor | Envelope glycoprotein gp160, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (15 entities in total) |
Functional Keywords | hiv-1 broadly neutralizing antibody, viral protein-immune system complex, immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 8 |
Total formula weight | 229340.44 |
Authors | Stanfield, R.L.,Wilson, I.A. (deposition date: 2019-04-24, release date: 2020-04-01, Last modification date: 2023-10-11) |
Primary citation | Stanfield, R.L.,Berndsen, Z.T.,Huang, R.,Sok, D.,Warner, G.,Torres, J.L.,Burton, D.R.,Ward, A.B.,Wilson, I.A.,Smider, V.V. Structural basis of broad HIV neutralization by a vaccine-induced cow antibody. Sci Adv, 6:eaba0468-eaba0468, 2020 Cited by PubMed: 32518821DOI: 10.1126/sciadv.aba0468 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (4.084 Å) |
Structure validation
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