PDB: 467 件ウェブページステータス検索Chemie searchBIRD

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6M2W	Structure of RyR1 (Ca2+/Caffeine/ATP/CaM1234/CHL) 分子名称: 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ... 著者 Ma, R, Haji-Ghassemi, O, Ma, D, Lin, L, Samurkas, A, Van Petegem, F, Yuchi, Z. 登録日 2020-03-01 公開日 2020-09-02 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Structural basis for diamide modulation of ryanodine receptor. Nat.Chem.Biol., 16, 2020
7CF9	Structure of RyR1 (Ca2+/CHL) 分子名称: 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ... 著者 Ma, R, Haji-Ghassemi, O, Ma, D, Lin, L, Samurkas, A, Van Petegem, F, Yuchi, Z. 登録日 2020-06-24 公開日 2020-09-02 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (4.7 Å) 主引用文献 Structural basis for diamide modulation of ryanodine receptor. Nat.Chem.Biol., 16, 2020
6M4V	Crystal structure of MBP fused split FKBP in complex with rapamycin 分子名称: GLYCEROL, Peptidyl-prolyl cis-trans isomerase FKBP1A, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, ... 著者 Kikuchi, M, Wu, D, Inoue, T, Umehara, T. 登録日 2020-03-09 公開日 2020-08-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.92 Å) 主引用文献 Rational design and implementation of a chemically inducible heterotrimerization system. Nat.Methods, 17, 2020
6M4U	Crystal structure of FKBP-FRB T2098L mutant in complex with rapamycin 分子名称: CHLORIDE ION, GLYCEROL, Peptidyl-prolyl cis-trans isomerase FKBP1A, ... 著者 Kikuchi, M, Wu, D, Inoue, T, Umehara, T. 登録日 2020-03-09 公開日 2020-08-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Rational design and implementation of a chemically inducible heterotrimerization system. Nat.Methods, 17, 2020
6M4W	Crystal structure of MBP fused split FKBP-FRB T2098L mutant in complex with rapamycin 分子名称: GLYCEROL, Peptidyl-prolyl cis-trans isomerase FKBP1A, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, ... 著者 Kikuchi, M, Wu, D, Inoue, T, Umehara, T. 登録日 2020-03-09 公開日 2020-08-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3.11 Å) 主引用文献 Rational design and implementation of a chemically inducible heterotrimerization system. Nat.Methods, 17, 2020
7JMF	Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 42 - State 6 (S6) 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... 著者 Dashti, A, des Georges, A, Frank, J, Ourmazd, A. 登録日 2020-07-31 公開日 2020-08-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
6PV6	Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ... 著者 Dashti, A, des Georges, A, Frank, J, Ourmazd, A. 登録日 2019-07-19 公開日 2020-08-12 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
7JMI	Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 29 - State 3 (S3) 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... 著者 Dashti, A, des Georges, A, Frank, J, Ourmazd, A. 登録日 2020-07-31 公開日 2020-08-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
7JMJ	Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 37 - State 5 (S5) 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... 著者 Dashti, A, des Georges, A, Frank, J, Ourmazd, A. 登録日 2020-07-31 公開日 2020-08-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
7JMG	Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 22 - State 2 (S2) 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... 著者 Dashti, A, des Georges, A, Frank, J, Ourmazd, A. 登録日 2020-07-31 公開日 2020-08-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
7JMH	Functional Pathways of Biomolecules Retrieved from Single-particle Snapshots - Frame 35 - State 4 (S4) 分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... 著者 Dashti, A, des Georges, A, Frank, J, Ourmazd, A. 登録日 2020-07-31 公開日 2020-08-12 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.5 Å) 主引用文献 Retrieving functional pathways of biomolecules from single-particle snapshots. Nat Commun, 11, 2020
6WOU	Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 mutant R176Q in complex with FKBP12.6 in nanodisc 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION 著者 Iyer, K.A, Hu, Y, Kurebayashi, N, Murayama, T, Samso, M. 登録日 2020-04-25 公開日 2020-08-05 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM. Sci Adv, 6, 2020
6WOV	Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 wild type in complex with FKBP12.6 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION 著者 Iyer, K.A, Hu, Y, Nayak, A.R, Kurebayashi, N, Murayama, T, Samso, M. 登録日 2020-04-25 公開日 2020-08-05 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (5.1 Å) 主引用文献 Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM. Sci Adv, 6, 2020
6WOT	Cryo-EM structure of recombinant rabbit Ryanodine Receptor type 1 mutant R164C in complex with FKBP12.6 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION 著者 Iyer, K.A, Hu, Y, Kurebayashi, N, Murayama, T, Samso, M. 登録日 2020-04-25 公開日 2020-08-05 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.54 Å) 主引用文献 Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM. Sci Adv, 6, 2020
6TX4	CRYSTAL STRUCTURE OF HUMAN FKBP51 FK1 DOMAIN A19T MUTANT IN COMPLEX WITH 2-PYRIDONE 分子名称: 1~{H}-pyridin-2-one, CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase FKBP5, ... 著者 Fiegen, D, Draxler, S.W. 登録日 2020-01-13 公開日 2020-05-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.06 Å) 主引用文献 Hybrid Screening Approach for Very Small Fragments: X-ray and Computational Screening on FKBP51. J.Med.Chem., 63, 2020
6TX9	CRYSTAL STRUCTURE OF HUMAN FKBP51 FK1 DOMAIN A19T MUTANT IN COMPLEX WITH HYDANTOIN 分子名称: Peptidyl-prolyl cis-trans isomerase FKBP5, SODIUM ION, imidazolidine-2,4-dione 著者 Fiegen, D, Draxler, S.W. 登録日 2020-01-13 公開日 2020-05-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Hybrid Screening Approach for Very Small Fragments: X-ray and Computational Screening on FKBP51. J.Med.Chem., 63, 2020
6TX7	CRYSTAL STRUCTURE OF HUMAN FKBP51 FK1 DOMAIN A19T MUTANT IN COMPLEX WITH 2-PIPERIDONE 分子名称: CHLORIDE ION, Peptidyl-prolyl cis-trans isomerase FKBP5, SODIUM ION, ... 著者 Fiegen, D, Draxler, S.W. 登録日 2020-01-13 公開日 2020-05-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.13 Å) 主引用文献 Hybrid Screening Approach for Very Small Fragments: X-ray and Computational Screening on FKBP51. J.Med.Chem., 63, 2020
6TX8	CRYSTAL STRUCTURE OF HUMAN FKBP51 FK1 DOMAIN A19T MUTANT IN COMPLEX WITH IMIDAZOLE 分子名称: CHLORIDE ION, IMIDAZOLE, Peptidyl-prolyl cis-trans isomerase FKBP5, ... 著者 Fiegen, D, Draxler, S.W. 登録日 2020-01-13 公開日 2020-05-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Hybrid Screening Approach for Very Small Fragments: X-ray and Computational Screening on FKBP51. J.Med.Chem., 63, 2020
6TX5	CRYSTAL STRUCTURE OF HUMAN FKBP51 FK1 DOMAIN A19T MUTANT IN COMPLEX WITH 4-METHYLIMIDAZOLE 分子名称: 4-METHYLIMIDAZOLE, Peptidyl-prolyl cis-trans isomerase FKBP5, SODIUM ION 著者 Fiegen, D, Draxler, S.W. 登録日 2020-01-13 公開日 2020-05-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.08 Å) 主引用文献 Hybrid Screening Approach for Very Small Fragments: X-ray and Computational Screening on FKBP51. J.Med.Chem., 63, 2020
6TX6	CRYSTAL STRUCTURE OF HUMAN FKBP51 FK1 DOMAIN A19T MUTANT IN COMPLEX WITH NICOTINAMIDE 分子名称: CHLORIDE ION, NICOTINAMIDE, Peptidyl-prolyl cis-trans isomerase FKBP5, ... 著者 Fiegen, D, Draxler, S.W. 登録日 2020-01-13 公開日 2020-05-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (0.98 Å) 主引用文献 Hybrid Screening Approach for Very Small Fragments: X-ray and Computational Screening on FKBP51. J.Med.Chem., 63, 2020
6TXX	CRYSTAL STRUCTURE OF HUMAN FKBP51 FK1 DOMAIN A19T MUTANT IN COMPLEX WITH SAFit2 分子名称: (1R)-3-(3,4-dimethoxyphenyl)-1-{3-[2-(morpholin-4-yl)ethoxy]phenyl}propyl (2S)-1-[(2S)-2-[(1S)-cyclohex-2-en-1-yl]-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxylate, Peptidyl-prolyl cis-trans isomerase FKBP5 著者 Fiegen, D, Draxler, S.W. 登録日 2020-01-14 公開日 2020-05-27 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Hybrid Screening Approach for Very Small Fragments: X-ray and Computational Screening on FKBP51. J.Med.Chem., 63, 2020
6RCY	CRYSTAL STRUCTURE OF FK1 DOMAIN OF FKBP52 IN COMPLEX WITH A BIO-INSPIRED HYBRID FLUORESCENT LIGAND 分子名称: (2~{S})-5-carbamimidamido-2-[[(2~{S})-2-[[(2~{S})-1-[5-(dimethylamino)naphthalen-1-yl]sulfonylpiperidin-2-yl]carbonylamino]-4-phenyl-butanoyl]amino]pentanoic acid, Peptidyl-prolyl cis-trans isomerase FKBP4 著者 Li de la Sierra-Gallay, I, Byrne, C. 登録日 2019-04-12 公開日 2020-05-13 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Bioinspired Hybrid Fluorescent Ligands for the FK1 Domain of FKBP52. J.Med.Chem., 63, 2020
6OQA	Crystal structure of CEP250 bound to FKBP12 in the presence of FK506-like novel natural product 分子名称: (3R,4E,7E,10R,11S,12R,13S,16R,17R,24aS)-11,17-dihydroxy-10,12,16-trimethyl-3-[(2R)-1-phenylbutan-2-yl]-6,9,10,11,12,13,14,15,16,17,22,23,24,24a-tetradecahydro-3H-13,17-epoxypyrido[2,1-c][1,4]oxazacyclohenicosine-1,18,19(21H)-trione, 1,2-ETHANEDIOL, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, ... 著者 Lee, S.-J, Shigdel, U.K, Townson, S.A, Verdine, G.L. 登録日 2019-04-26 公開日 2020-04-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface. Proc.Natl.Acad.Sci.USA, 117, 2020
6VSI	Crystal structure of FKBP12 of Candida auris 分子名称: Peptidylprolyl isomerase, SULFATE ION 著者 Li, Z, Li, H, Hernandez, G, LeMaster, D. 登録日 2020-02-11 公開日 2020-04-01 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Crystal structure and transient dimerization for the FKBP12 protein from the pathogenic fungus Candida auris. Biochem.Biophys.Res.Commun., 525, 2020
6O4A	CRYSTAL STRUCTURE OF SMT FUSION PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FROM BURKHOLDERIA PSEUDOMALLEI COMPLEXED WITH SF355 分子名称: 2-(pyridin-3-ylcarbonylamino)ethyl (2~{S})-1-(phenylmethyl)sulfonylpiperidine-2-carboxylate, CALCIUM ION, Ubiquitin-like protein SMT3,Peptidyl-prolyl cis-trans isomerase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2019-02-28 公開日 2020-02-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 CRYSTAL STRUCTURE OF SMT FUSION PEPTIDYL-PROLYL CIS-TRANS ISOMERASE FROM BURKHOLDERIA PSEUDOMALLEI COMPLEXED WITH SF355 to be published

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