6TX5

CRYSTAL STRUCTURE OF HUMAN FKBP51 FK1 DOMAIN A19T MUTANT IN COMPLEX WITH 4-METHYLIMIDAZOLE

Summary for 6TX5

Entry DOI	10.2210/pdb6tx5/pdb
Descriptor	Peptidyl-prolyl cis-trans isomerase FKBP5, SODIUM ION, 4-METHYLIMIDAZOLE, ... (4 entities in total)
Functional Keywords	ppiase, fragment, isomerase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	14154.16
Authors	Fiegen, D.,Draxler, S.W. (deposition date: 2020-01-13, release date: 2020-05-27, Last modification date: 2024-01-24)
Primary citation	Draxler, S.W.,Bauer, M.,Eickmeier, C.,Nadal, S.,Nar, H.,Rangel Rojas, D.,Seeliger, D.,Zeeb, M.,Fiegen, D. Hybrid Screening Approach for Very Small Fragments: X-ray and Computational Screening on FKBP51. J.Med.Chem., 63:5856-5864, 2020 Cited by PubMed: 32420743 DOI: 10.1021/acs.jmedchem.0c00120 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.08 Å)

Structure validation