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8FJ3
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BU of 8fj3 by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL7(Y13A)
分子名称: C-C motif chemokine 7, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2022-12-19
公開日2023-03-29
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
8FJ2
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BU of 8fj2 by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001(C8) Complexed to Human Chemokine CCL17
分子名称: C-C motif chemokine 17, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2022-12-19
公開日2023-03-29
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
8FK8
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BU of 8fk8 by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001(L39P) Complexed to Human Chemokine CCL7
分子名称: C-C motif chemokine 7, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2022-12-20
公開日2023-03-29
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
8FJ0
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BU of 8fj0 by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001(Y44A) Complexed to Human Chemokine CCL2
分子名称: C-C motif chemokine 2, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2022-12-18
公開日2023-03-29
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
8FK6
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BU of 8fk6 by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001(Y44A) Complexed to Human Chemokine CCL7
分子名称: C-C motif chemokine 7, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2022-12-20
公開日2023-03-29
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
2FIN
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BU of 2fin by Molmil
Solution Structure of the complex between poxvirus-encoded CC chemokine inhibitor vCCI and human MIP-1beta, ensemble structure
分子名称: Small inducible cytokine A4, rabbitpox encoded CC chemokine inhibitor
著者Zhang, L.
登録日2005-12-29
公開日2006-08-22
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Solution structure of the complex between poxvirus-encoded CC chemokine inhibitor vCCI and human MIP-1beta.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2FFK
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BU of 2ffk by Molmil
Solution structure of the complex between poxvirus-encoded CC chemokine inhibitor vCCI and human MIP-1beta, minimized average structure
分子名称: Small inducible cytokine A4, rabbitpox encoded CC chemokine inhibitor
著者Zhang, L.
登録日2005-12-19
公開日2006-08-22
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Solution structure of the complex between poxvirus-encoded CC chemokine inhibitor vCCI and human MIP-1beta.
Proc.Natl.Acad.Sci.Usa, 103, 2006
7S4N
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BU of 7s4n by Molmil
Crystal structure of the tick evasin EVA-P974 complexed to human chemokine CCL17
分子名称: C-C motif chemokine 17, Evasin P974
著者Bhusal, R.P, Devkota, S.R, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2021-09-09
公開日2022-03-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases.
Proc.Natl.Acad.Sci.USA, 119, 2022
7S59
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BU of 7s59 by Molmil
Crystal structure of the tick evasin EVA-P974 complexed to a chimera made of human chemokines CCL7 and CCL8
分子名称: Evasin P974, SULFATE ION, chimera protein of C-C motif chemokine 7 and C-C motif chemokine 8,C-C motif chemokine 7
著者Bhusal, R.P, Devkota, S.R, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2021-09-10
公開日2022-03-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases.
Proc.Natl.Acad.Sci.USA, 119, 2022
7S58
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BU of 7s58 by Molmil
Crystal Structure of the tick evasin EVA-P974 complexed to human chemokine CCL7
分子名称: C-C motif chemokine 7, Evasin P974
著者Bhusal, R.P, Devkota, S.R, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2021-09-10
公開日2022-03-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structure-guided engineering of tick evasins for targeting chemokines in inflammatory diseases.
Proc.Natl.Acad.Sci.USA, 119, 2022
7SCS
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BU of 7scs by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL11
分子名称: Eotaxin, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2021-09-29
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
7SCV
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BU of 7scv by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL17
分子名称: C-C motif chemokine 17, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2021-09-29
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
7SCU
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BU of 7scu by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL7
分子名称: C-C motif chemokine 7, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2021-09-29
公開日2023-04-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Crystal Structure of Tick Evasin EVA-AAM1001 complexed to human chemokine CCL7
To Be Published
7SCT
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BU of 7sct by Molmil
Crystal Structure of the Tick Evasin EVA-AAM1001 Complexed to Human Chemokine CCL16
分子名称: C-C motif chemokine 16, Evasin P1243
著者Devkota, S.R, Bhusal, R.P, Aryal, P, Wilce, M.C.J, Stone, M.J.
登録日2021-09-29
公開日2023-03-29
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Engineering broad-spectrum inhibitors of inflammatory chemokines from subclass A3 tick evasins.
Nat Commun, 14, 2023
4RAL
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BU of 4ral by Molmil
Crystal structure of insulin degrading enzyme in complex with macrophage inflammatory protein 1 beta
分子名称: C-C motif chemokine 4, Insulin-degrading enzyme, ZINC ION
著者Liang, W.G, Ren, M, Guo, Q, Tang, W.J.
登録日2014-09-10
公開日2015-05-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.148 Å)
主引用文献Structures of human CCL18, CCL3, and CCL4 reveal molecular determinants for quaternary structures and sensitivity to insulin-degrading enzyme.
J.Mol.Biol., 427, 2015
5CBA
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BU of 5cba by Molmil
3B4 in complex with CXCL13 - 3B4-CXCL13
分子名称: 1,2-ETHANEDIOL, 3b4 heavy chain, 3b4 light chain, ...
著者Tu, C, Bard, J, Mosyak, L.
登録日2015-06-30
公開日2015-11-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A Combination of Structural and Empirical Analyses Delineates the Key Contacts Mediating Stability and Affinity Increases in an Optimized Biotherapeutic Single-chain Fv (scFv).
J. Biol. Chem., 291, 2016
5CBE
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BU of 5cbe by Molmil
E10 in complex with CXCL13
分子名称: 1,2-ETHANEDIOL, C-X-C motif chemokine 13, E10 heavy chain, ...
著者Tu, C, Bard, J, Mosyak, L.
登録日2015-06-30
公開日2015-11-04
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Combination of Structural and Empirical Analyses Delineates the Key Contacts Mediating Stability and Affinity Increases in an Optimized Biotherapeutic Single-chain Fv (scFv).
J. Biol. Chem., 291, 2016
2N55
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BU of 2n55 by Molmil
Structure of constitutively monomeric CXCL12 in complex with the CXCR4 N-terminus
分子名称: C-X-C chemokine receptor type 4, Stromal cell-derived factor 1
著者Ziarek, J.J, Peterson, F.C, Volkman, B.F.
登録日2015-07-07
公開日2016-04-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis for chemokine recognition by a G protein-coupled receptor and implications for receptor activation.
Sci Signal, 10, 2017
2NYZ
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BU of 2nyz by Molmil
Viral Chemokine Binding Protein M3 From Murine Gammaherpesvirus68 In Complex With The C- Chemokine XCL1
分子名称: Hypothetical protein GAMMAHV.M3, Lymphotactin
著者Alexander-Brett, J.M, Fremont, D.H.
登録日2006-11-21
公開日2007-12-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Dual GPCR and GAG mimicry by the M3 chemokine decoy receptor.
J.Exp.Med., 204, 2007
2NZ1
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BU of 2nz1 by Molmil
Viral Chemokine Binding Protein M3 From Murine Gammaherpesvirus68 In Complex With The CC-Chemokine CCL2/MCP-1
分子名称: Hypothetical protein GAMMAHV.M3, Small inducible cytokine A2
著者Alexander-Brett, J.M, Fremont, D.H.
登録日2006-11-22
公開日2007-12-25
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Dual GPCR and GAG mimicry by the M3 chemokine decoy receptor.
J.Exp.Med., 204, 2007
1ML0
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BU of 1ml0 by Molmil
VIRAL CHEMOKINE BINDING PROTEIN M3 FROM MURINE GAMMAHERPESVIRUS68 IN COMPLEX WITH THE P8A VARIANT OF CC-CHEMOKINE MCP-1
分子名称: M3 Protein, Small Inducible Cytokine
著者Alexander, J.M, Fremont, D.H.
登録日2002-08-29
公開日2002-11-13
最終更新日2021-10-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis of Chemokine Sequestration by a Herpesvirus Decoy Receptor
Cell(Cambridge,Mass.), 111, 2002
2K05
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BU of 2k05 by Molmil
Structure of SDF1 in complex with the CXCR4 N-terminus containing sulfotyrosines at postitions 7, 12 and 21
分子名称: C-X-C chemokine receptor type 4, Stromal cell-derived factor 1
著者Volkman, B.F, Veldkamp, C.T, Peterson, F.C.
登録日2008-01-24
公開日2008-10-28
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12.
Sci.Signal., 1, 2008
2K03
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BU of 2k03 by Molmil
Structure of SDF1 in complex with the CXCR4 N-terminus containing a sulfotyrosine at postition 21
分子名称: C-X-C chemokine receptor type 4, Stromal cell-derived factor 1
著者Volkman, B.F, Veldkamp, C.T, Peterson, F.C.
登録日2008-01-24
公開日2008-10-28
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12
Sci.Signal., 1, 2008
2K04
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BU of 2k04 by Molmil
Structure of SDF1 in complex with the CXCR4 N-terminus containing no sulfotyrosines
分子名称: C-X-C chemokine receptor type 4, Stromal cell-derived factor 1
著者Volkman, B.F, Veldkamp, C.T, Peterson, F.C.
登録日2008-01-24
公開日2008-10-28
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structural basis of CXCR4 sulfotyrosine recognition by the chemokine SDF-1/CXCL12
Sci.Signal., 1, 2008
8K2X
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BU of 8k2x by Molmil
CXCR3-DNGi complex activated by CXCL10
分子名称: C-X-C motif chemokine 10, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Jiao, H.Z, Hu, H.L.
登録日2023-07-14
公開日2023-11-29
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure basis for the modulation of CXC chemokine receptor 3 by antagonist AMG487.
Cell Discov, 9, 2023

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件を2024-06-12に公開中

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