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6VFU
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BU of 6vfu by Molmil
Crystal structure of human protocadherin 19 EC1-EC4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Harrison, O.J, Brasch, J, Shapiro, L.
登録日2020-01-06
公開日2020-03-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
6VFR
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BU of 6vfr by Molmil
Crystal structure of human protocadherin 18 EC1-EC4
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Harrison, O.J, Brasch, J, Shapiro, L.
登録日2020-01-06
公開日2020-03-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
6VG1
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BU of 6vg1 by Molmil
xenopus protocadherin 8.1 EC1-6
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Harrison, O.J, Brasch, B, Shapiro, L.S.
登録日2020-01-07
公開日2020-03-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
6VFW
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BU of 6vfw by Molmil
Crystal structure of human delta protocadherin 10 EC1-EC4
分子名称: CALCIUM ION, Protocadherin-10, alpha-D-mannopyranose, ...
著者Harrison, O.J, Brasch, J, Shapiro, L.
登録日2020-01-06
公開日2020-03-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
6VFQ
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BU of 6vfq by Molmil
Crystal structure of monomeric human protocadherin 10 EC1-EC4
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者Harrison, O.J, Brasch, J, Shapiro, L.
登録日2020-01-06
公開日2020-03-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
6VFV
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BU of 6vfv by Molmil
Crystal structure of human protocadherin 8 EC5-EC6
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
著者Harrison, O.J, Brasch, J, Shapiro, L.
登録日2020-01-06
公開日2020-03-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins.
Cell Rep, 30, 2020
6PSF
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BU of 6psf by Molmil
Rhinovirus C15 complexed with domains I and II of receptor CDHR3
分子名称: Cadherin-related family member 3, Capsid protein VP1, Capsid protein VP2, ...
著者Sun, Y, Watters, K, Klose, T, Palmenberg, A.C.
登録日2019-07-12
公開日2020-03-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of rhinovirus C15a bound to its cadherin-related protein 3 receptor.
Proc.Natl.Acad.Sci.USA, 117, 2020
7AGG
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BU of 7agg by Molmil
HAd7 knob in complex with 2 EC2-EC3 modules of DSG-2
分子名称: Desmoglein-2, Fiber
著者Effantin, G, Vassal-Stermann, E, Fender, P.
登録日2020-09-22
公開日2020-10-14
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Binding Mechanism Elucidation of the Acute Respiratory Disease Causing Agent Adenovirus of Serotype 7 to Desmoglein-2.
Viruses, 12, 2020
7AGF
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BU of 7agf by Molmil
HAd7 knob in complex with 3 EC2-EC3 modules of DSG-2
分子名称: Desmoglein-2, Fiber
著者Effantin, G, Vassal-Stermann, E, Fender, P.
登録日2020-09-22
公開日2020-10-14
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Binding Mechanism Elucidation of the Acute Respiratory Disease Causing Agent Adenovirus of Serotype 7 to Desmoglein-2.
Viruses, 12, 2020
7A7D
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BU of 7a7d by Molmil
Cadherin fit into cryo-ET map
分子名称: Desmocollin-2, Desmoglein-2
著者Sikora, M, Ermel, U.H, Seybold, A, Kunz, M, Calloni, G, Reitz, J, Vabulas, R.M, Hummer, G, Frangakis, A.S.
登録日2020-08-28
公開日2020-12-23
実験手法ELECTRON MICROSCOPY (26 Å)
主引用文献Desmosome architecture derived from molecular dynamics simulations and cryo-electron tomography.
Proc.Natl.Acad.Sci.USA, 117, 2020
6PGW
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BU of 6pgw by Molmil
Crystal structure of zebrafish Protocadherin-19 EC3-6
分子名称: CALCIUM ION, Protocadherin-19, SODIUM ION
著者Cooper, S.R, Hudson, J.D, Sotomayor, M.
登録日2019-06-24
公開日2020-12-30
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献A complete Protocadherin-19 ectodomain model for evaluating epilepsy-causing mutations and potential protein interaction sites.
Structure, 29, 2021
7AML
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BU of 7aml by Molmil
RET/GDNF/GFRa1 extracellular complex Cryo-EM structure
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GDNF family receptor alpha, ...
著者Adams, S.E, Earl, C.P, Purkiss, A.G, McDonald, N.Q.
登録日2020-10-09
公開日2021-01-13
最終更新日2021-07-14
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献A two-site flexible clamp mechanism for RET-GDNF-GFR alpha 1 assembly reveals both conformational adaptation and strict geometric spacing.
Structure, 29, 2021
7AMK
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BU of 7amk by Molmil
Zebrafish RET Cadherin Like Domains 1 to 4.
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Purkiss, A.G, McDonald, N.Q, Goodman, K.M, Narowtek, A, Knowles, P.P.
登録日2020-10-09
公開日2021-02-03
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A two-site flexible clamp mechanism for RET-GDNF-GFR alpha 1 assembly reveals both conformational adaptation and strict geometric spacing.
Structure, 29, 2021
6ULM
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BU of 6ulm by Molmil
Crystal structure of human cadherin 17 EC1-2
分子名称: CALCIUM ION, Cadherin-17
著者Gray, M.E, Sotomayor, M.
登録日2019-10-08
公開日2021-03-17
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Crystal structure of the nonclassical cadherin-17 N-terminus and implications for its adhesive binding mechanism.
Acta Crystallogr.,Sect.F, 77, 2021
6ZTB
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BU of 6ztb by Molmil
Crystal Structure of human P-Cadherin EC1_EC2
分子名称: CALCIUM ION, Cadherin-3, SODIUM ION
著者Rondeau, J.M, Lehmann, S.
登録日2020-07-17
公開日2021-05-05
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies.
Mol.Cancer Ther., 20, 2021
6ZTR
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BU of 6ztr by Molmil
Crystal Structure of the anti-human P-Cadherin Fab CQY684 in complex with human P-Cadherin(108-324)
分子名称: CALCIUM ION, CQY684 Fab heavy-chain, CQY684 Fab light-chain, ...
著者Rondeau, J.M, Lehmann, S.
登録日2020-07-20
公開日2021-05-05
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies.
Mol.Cancer Ther., 20, 2021
7EV1
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BU of 7ev1 by Molmil
Crystal structure of LI-Cadherin EC1-2
分子名称: ACETATE ION, CALCIUM ION, Cadherin-17, ...
著者Caaveiro, J.M.M, Yui, A, Tsumoto, K.
登録日2021-05-19
公開日2021-06-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.38 Å)
主引用文献Mechanism of dimerization and structural features of human LI-cadherin.
J.Biol.Chem., 297, 2021
7JGZ
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BU of 7jgz by Molmil
Protocadherin gammaC4 EC1-4 crystal structure
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Goodman, K.M, Mannepalli, S, Honig, B, Shapiro, L.
登録日2020-07-20
公開日2021-07-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.51 Å)
主引用文献How clustered protocadherin binding specificity is tuned for neuronal self-/nonself-recognition.
Elife, 11, 2022
7CYM
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BU of 7cym by Molmil
Crystal structure of LI-Cadherin EC1-4
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Caaveiro, J.M.M, Yui, A, Tsumoto, K.
登録日2020-09-03
公開日2021-08-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Mechanism of dimerization and structural features of human LI-cadherin.
J.Biol.Chem., 297, 2021
7N86
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BU of 7n86 by Molmil
Crystal Structure of Human Protocadherin-24 EC1-2 Form II
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, CHLORIDE ION, ...
著者Modak, D, Gray, M.E, Sotomayor, M.
登録日2021-06-13
公開日2021-09-01
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.175 Å)
主引用文献Heterophilic and homophilic cadherin interactions in intestinal intermicrovillar links are species dependent.
Plos Biol., 19, 2021
7CMF
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BU of 7cmf by Molmil
Crystal structure of human P-cadherin REC12 (monomer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor)
分子名称: 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3
著者Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K.
登録日2020-07-27
公開日2021-09-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
Commun Biol, 4, 2021
7CME
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BU of 7cme by Molmil
Crystal structure of human P-cadherin MEC12 (X dimer) in complex with 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine (inhibitor)
分子名称: 2-(5-chloro-2-methyl-1H-indol-3-yl)ethan-1-amine, CALCIUM ION, Cadherin-3, ...
著者Senoo, A, Ito, S, Ueno, G, Nagatoishi, S, Tsumoto, K.
登録日2020-07-27
公開日2021-09-15
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Regulation of cadherin dimerization by chemical fragments as a trigger to inhibit cell adhesion
Commun Biol, 4, 2021
7STZ
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BU of 7stz by Molmil
Crystal Structure of Human E-cadherin EC1-5 bound by mouse monoclonal antibody Fab mAb-1_19A11
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2021-11-15
公開日2022-01-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Regulation of multiple dimeric states of E-cadherin by adhesion activating antibodies revealed through Cryo-EM and X-ray crystallography.
Pnas Nexus, 1, 2022
7RGF
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BU of 7rgf by Molmil
Protocadherin gammaC4 EC1-4 crystal structure disrupted trans interface
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Goodman, K.M, Mannepalli, S, Honig, B, Shapiro, L.
登録日2021-07-15
公開日2022-03-16
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献How clustered protocadherin binding specificity is tuned for neuronal self-/nonself-recognition.
Elife, 11, 2022
7N4P
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BU of 7n4p by Molmil
Crystal Structure of Lizard Cadherin-23 EC1-2
分子名称: CALCIUM ION, Cadherin 23, SODIUM ION
著者Nisler, C.R, Sotomayor, M.
登録日2021-06-04
公開日2022-06-15
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.097 Å)
主引用文献Interpreting the Evolutionary Echoes of a Protein Complex Essential for Inner-Ear Mechanosensation.
Mol.Biol.Evol., 40, 2023

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