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4RTW
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BU of 4rtw by Molmil
Crystal structure of the c-Src-SH3 domain E93V/Q128R mutant in complex with the high affinity peptide APP12
分子名称: APP12 peptide, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ...
著者Camara-Artigas, A, Bacarizo, J.
登録日2014-11-16
公開日2015-10-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.24 Å)
主引用文献Crystal structure of the c-Src-SH3 domain E93V/Q128R mutant in complex with the high affinity peptide APP12
To be Published
4U5W
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BU of 4u5w by Molmil
Crystal Structure of HIV-1 Nef-SF2 Core Domain in Complex with the Src Family Kinase Hck SH3-SH2 Tandem Regulatory Domains
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, IODIDE ION, Protein Nef, ...
著者Alvarado, J.J, Yeh, J.I, Smithgall, T.E.
登録日2014-07-25
公開日2014-08-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Interaction with the Src Homology (SH3-SH2) Region of the Src-family Kinase Hck Structures the HIV-1 Nef Dimer for Kinase Activation and Effector Recruitment.
J.Biol.Chem., 289, 2014
4QT7
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BU of 4qt7 by Molmil
Crystal structure of the c-Src SH3 domain in complex with a peptide from the Hepatitis C virus NS5A-protein
分子名称: NS5A, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A, Bacarizo, J.
登録日2014-07-07
公開日2014-12-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structure of the c-Src-SH3 domain in complex with a proline-rich motif of NS5A protein from the hepatitis C virus.
J.Struct.Biol., 189, 2015
2MOX
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BU of 2mox by Molmil
solution structure of tandem SH3 domain of Sorbin and SH3 domain-containing protein 1
分子名称: Sorbin and SH3 domain-containing protein 1
著者Zhao, D, Wang, C, Zhang, J, Wu, J, Shi, Y, Zhang, Z, Gong, Q.
登録日2014-05-07
公開日2014-05-28
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
4ORZ
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BU of 4orz by Molmil
HIV-1 Nef protein in complex with single domain antibody sdAb19 and an engineered Hck SH3 domain
分子名称: Protein Nef, Tyrosine-protein kinase HCK, single domain antibody sdAb19
著者Geyer, M, Lulf, S.
登録日2014-02-12
公開日2014-03-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for the inhibition of HIV-1 Nef by a high-affinity binding single-domain antibody.
Retrovirology, 11, 2014
4OMM
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BU of 4omm by Molmil
Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant N113S
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ...
著者Camara-Artigas, A, Bacarizo, J.
登録日2014-01-27
公開日2015-01-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The role of Gutamine 128 of the SH3 domain of the c-Src tyrosine kinase in 3D domain swapping and amyloid formation
To be Published
4OMO
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BU of 4omo by Molmil
Crystal structure of the c-Src tyrosine kinase SH3 domain mutant Q128E
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A, Bacarizo, J.
登録日2014-01-27
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
4OML
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BU of 4oml by Molmil
Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128R
分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
著者Camara-Artigas, A, Bacarizo, J.
登録日2014-01-27
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
4OMN
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BU of 4omn by Molmil
Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128E
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, Proto-oncogene tyrosine-protein kinase Src, ...
著者Camara-Artigas, A, Bacarizo, J.
登録日2014-01-27
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
4OMQ
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BU of 4omq by Molmil
Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant S94A
分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, SULFATE ION, ...
著者Camara-Artigas, A, Bacarizo, J.
登録日2014-01-27
公開日2015-01-28
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The role of Gutamine 128 of the SH3 domain of the c-Src tyrosine kinase in 3D domain swapping and amyloid formation
To be Published
4OMP
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BU of 4omp by Molmil
Crystal structure of the intertwined dimer of the c-Src tyrosine kinase SH3 domain mutant Q128K
分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
著者Camara-Artigas, A, Bacarizo, J.
登録日2014-01-27
公開日2014-12-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
4N78
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BU of 4n78 by Molmil
The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton
分子名称: Abl interactor 2, CHLORIDE ION, Cytoplasmic FMR1-interacting protein 1, ...
著者Chen, Z.C.
登録日2013-10-15
公開日2014-02-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.43 Å)
主引用文献The WAVE Regulatory Complex Links Diverse Receptors to the Actin Cytoskeleton.
Cell(Cambridge,Mass.), 156, 2014
4M4Z
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BU of 4m4z by Molmil
SH3 and SH2 domains of human Src-like adaptor protein 2 (SLAP2)
分子名称: Src-like-adapter 2
著者Wybenga-Groot, L.E, McGlade, C.J.
登録日2013-08-07
公開日2013-11-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Src-like adaptor protein 2 reveals close association of SH3 and SH2 domains through beta-sheet formation.
Cell Signal, 25, 2013
4LUD
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BU of 4lud by Molmil
Crystal Structure of HCK in complex with the fluorescent compound SKF86002
分子名称: 6-(4-fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole, CALCIUM ION, CHLORIDE ION, ...
著者Parker, L.J, Tanaka, A, Handa, N, Honda, K, Tomabechi, Y, Shirouzu, M, Yokoyama, S.
登録日2013-07-25
公開日2014-02-12
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002.
Acta Crystallogr.,Sect.D, 70, 2014
4LUE
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BU of 4lue by Molmil
Crystal Structure of HCK in complex with 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (resulting from displacement of SKF86002)
分子名称: 7-[trans-4-(4-methylpiperazin-1-yl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, CALCIUM ION, CHLORIDE ION, ...
著者Parker, L.J, Tanaka, A, Handa, N, Honda, K, Tomabechi, Y, Shirouzu, M, Yokoyama, S.
登録日2013-07-25
公開日2014-02-12
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002.
Acta Crystallogr.,Sect.D, 70, 2014
4LN2
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BU of 4ln2 by Molmil
The second SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin
分子名称: Sorbin and SH3 domain-containing protein 1, proline rich peptide
著者Zhao, D, Li, F, Wu, J, Shi, Y, Zhang, Z, Gong, Q.
登録日2013-07-11
公開日2014-05-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Structural investigation of the interaction between the tandem SH3 domains of c-Cbl-associated protein and vinculin
J.Struct.Biol., 187, 2014
4LE9
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BU of 4le9 by Molmil
Crystal structure of a chimeric c-Src-SH3 domain
分子名称: Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
著者Camara-Artigas, A, Martinez-Rodriguez, S, Ortiz-Salmeron, E, Martin-Garcia, J.M.
登録日2013-06-25
公開日2014-05-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.344 Å)
主引用文献3D domain swapping in a chimeric c-Src SH3 domain takes place through two hinge loops.
J.Struct.Biol., 186, 2014
4K11
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BU of 4k11 by Molmil
The structure of 1NA in complex with Src T338G
分子名称: 1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Proto-oncogene tyrosine-protein kinase Src
著者Eck, M.J, Yun, C.H.
登録日2013-04-04
公開日2014-04-09
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of 1NA in complex with Src T338G
To be Published
4JZ4
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BU of 4jz4 by Molmil
Crystal structure of chicken c-Src-SH3 domain: monomeric form
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, NICKEL (II) ION, Proto-oncogene tyrosine-protein kinase Src
著者Camara-Artigas, A.
登録日2013-04-02
公開日2014-04-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
4JZ3
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BU of 4jz3 by Molmil
Crystal structure of the chicken c-Src-SH3 domain intertwined dimer
分子名称: DI(HYDROXYETHYL)ETHER, Proto-oncogene tyrosine-protein kinase Src, TRIETHYLENE GLYCOL
著者Camara-Artigas, A.
登録日2013-04-02
公開日2014-04-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.852 Å)
主引用文献Electrostatic Effects in the Folding of the SH3 Domain of the c-Src Tyrosine Kinase: pH-Dependence in 3D-Domain Swapping and Amyloid Formation.
Plos One, 9, 2014
4JJC
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BU of 4jjc by Molmil
Crystal structure of the Abl-SH3 domain at pH5
分子名称: DI(HYDROXYETHYL)ETHER, Tyrosine-protein kinase ABL1
著者Camara-Artigas, A, Martin-Garcia, J.M.
登録日2013-03-07
公開日2014-03-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the Abl-SH3 domain at pH5
To be Published
4JJB
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Crystal structure of the Abl-SH3 domain at pH3
分子名称: DI(HYDROXYETHYL)ETHER, SULFATE ION, Tyrosine-protein kinase ABL1
著者Camara-Artigas, A, Martin-Garcia, J.M.
登録日2013-03-07
公開日2014-03-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structure of the Abl-SH3 domain at pH3
To be Published
4JJD
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BU of 4jjd by Molmil
Crystal structure of the N114A Abl-SH3 domain mutant at pH4
分子名称: DI(HYDROXYETHYL)ETHER, SODIUM ION, Tyrosine-protein kinase ABL1
著者Camara-Artigas, A, Martin-Garcia, J.M.
登録日2013-03-07
公開日2014-03-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of the Abl-SH3 domain at pH5
To be Published
4J9I
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BU of 4j9i by Molmil
Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P17
分子名称: GLYCEROL, P17, Tyrosine-protein kinase ABL1
著者Camara-Artigas, A.
登録日2013-02-16
公開日2014-01-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the ABL-SH3 domain complexed with the designed high-affinity peptide ligand P17
To be Published
4J9F
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Crystal structure of the Abl-SH3 domain complexed with the high affinity peptide P0
分子名称: GLYCEROL, P0, SULFATE ION, ...
著者Camara-Artigas, A.
登録日2013-02-16
公開日2014-01-29
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.094 Å)
主引用文献Crystal structure of the Abl-SH3 domain complexed with the high affinity peptide P0
To be Published

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件を2024-07-10に公開中

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