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8QA2
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Cryo-EM structure of Cx26 solubilised in LMNG: classification on subunit A; Nconst-mon conformation
分子名称: Gap junction beta-2 protein, PHOSPHATIDYLETHANOLAMINE
著者Brotherton, D.H, Cameron, A.D.
登録日2023-08-22
公開日2024-06-12
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.3 Å)
主引用文献Structures of wild-type and a constitutively closed mutant of connexin26 shed light on channel regulation by CO 2.
Elife, 13, 2024
8Q9Y
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The structure of thiocyanate dehydrogenase from Pelomicrobium methylotrophicum in complex with inhibitor thiourea at 1.10 A resolution
分子名称: COPPER (II) ION, GLYCEROL, THIOUREA, ...
著者Varfolomeeva, L.A, Polyakov, K.M, Shipkov, N.S, Dergousova, N.I, Boyko, K.M, Tikhonova, T.V, Popov, V.O.
登録日2023-08-22
公開日2023-09-13
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Structure of thiocyanate dehydrogenase from Pelomicrobium methylotrophicum at atomic resolution
To Be Published
8Q9X
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The structure of thiocyanate dehydrogenase from Pelomicrobium methylotrophicum with molecular oxygen at 1.05 A resolution
分子名称: COPPER (II) ION, GLYCEROL, OXYGEN MOLECULE, ...
著者Varfolomeeva, L.A, Polyakov, K.M, Shipkov, N.S, Dergousova, N.I, Boyko, K.M, Tikhonova, T.V, Popov, V.O.
登録日2023-08-22
公開日2023-09-13
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Structure of thiocyanate dehydrogenase from Pelomicrobium methylotrophicum at atomic resolution
To Be Published
8Q9V
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S-methylthiourocanate hydratase from Variovorax sp. RA8 in complex with NAD+ and imidazolone propionate
分子名称: 1,2-ETHANEDIOL, 3-[(4~{R})-5-oxidanylidene-1,4-dihydroimidazol-4-yl]propanoic acid, ACETIC ACID, ...
著者Vasseur, C.M, Seebeck, F.P.
登録日2023-08-21
公開日2024-03-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and Substrate Specificity of S -Methyl Thiourocanate Hydratase.
Acs Chem.Biol., 19, 2024
8Q9U
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S-methylthiourocanate hydratase, variant R450A, from Variovorax sp. RA8 in complex with NAD+
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, urocanate hydratase
著者Vasseur, C.M, Seebeck, F.P.
登録日2023-08-21
公開日2024-03-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and Substrate Specificity of S -Methyl Thiourocanate Hydratase.
Acs Chem.Biol., 19, 2024
8Q9S
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BU of 8q9s by Molmil
STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA'; CSNK2A2 GENE PRODUCT) IN COMPLEX WITH THE INHIBITOR SGC-CK2-1
分子名称: 1,2-ETHANEDIOL, Casein kinase II subunit alpha', ~{N}-[5-[[3-cyano-7-(cyclopropylamino)-3~{H}-pyrazolo[1,5-a]pyrimidin-5-yl]amino]-2-methyl-phenyl]propanamide
著者Werner, C, Lindenblatt, D, Niefind, K.
登録日2023-08-21
公開日2023-12-06
実験手法X-RAY DIFFRACTION (1.352 Å)
主引用文献Discovery and Exploration of Protein Kinase CK2 Binding Sites Using CK2alpha Cys336Ser as an Exquisite Crystallographic Tool
Kinases Phosphatases, 2023
8Q9R
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Crystal structure of MADS-box/MEF2D N-terminal domain bound to dsDNA and HDAC9 deacetylase binding motif
分子名称: Histone deacetylase 9 (HDAC9) binding motif peptide: EVKQKLQEFLLSKS, MADS box dsDNA: AACTATTTATAAGA, MADS box dsDNA: TCTTATAAATAGT, ...
著者Chinellato, M, Carli, A, Perin, S, Mazzoccato, Y, Di Giorgio, E, Brancolini, C, Angelini, A, Cendron, L.
登録日2023-08-20
公開日2024-04-17
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.
J.Mol.Biol., 436, 2024
8Q9Q
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Crystal Structure of the MADS-box/MEF2 Domain of MEF2D bound to dsDNA and HDAC7 deacetylase binding motif
分子名称: HDAC7 (histone deacetylase 7) binding motif peptide: GLY-VAL-VAL-LYS-GLN-LYS-LEU-ALA-GLU-VAL-ILE-LEU-LYS-LYS-GLN, MADS box dsDNA: AACTATTTATAAGA, MADS box dsDNA: TCTTATAAATAGTT, ...
著者Chinellato, M, Carli, A, Perin, S, Mazzocato, Y, Biondi, B, Di Giorgio, E, Brancolini, C, Angelini, A, Cendron, L.
登録日2023-08-20
公開日2024-04-17
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.
J.Mol.Biol., 436, 2024
8Q9P
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Crystal Structure of the MADS-box/MEF2 Domain of MEF2D bound to dsDNA and HDAC5 deacetylase binding motif
分子名称: HDAC5 (histone deacetylase 5) binding motif peptide: TRP-GLY-SER-GLY-GLU-VAL-LYS-LEU-ARG-LEU-GLN-GLU-PHE-LEU-LEU-SER-LYS-SER, MADS box dsDNA fw: AACTATTTATAAGA, MADS box dsNA rev:TCTTATAAATAGTT, ...
著者Chinellato, M, Carli, A, Perin, S, Mazzocato, Y, Biondi, B, Di Giorgio, E, Brancolini, C, Angelini, A, Cendron, L.
登録日2023-08-20
公開日2024-04-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.
J.Mol.Biol., 436, 2024
8Q9N
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BU of 8q9n by Molmil
Crystal Structure of the MADS-box/MEF2 Domain of MEF2D bound to dsDNA and MITR deacetylase binding motif mutant L151V.
分子名称: DIMETHYL SULFOXIDE, DNA MADS box, MEF2D protein, ...
著者Chinellato, M, Carli, A, Perin, S, Mazzocato, Y, Biondi, B, Di Giorgio, E, Brancolini, C, Angelini, A, Cendron, L.
登録日2023-08-20
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Folding of Class IIa HDAC Derived Peptides into alpha-helices Upon Binding to Myocyte Enhancer Factor-2 in Complex with DNA.
J.Mol.Biol., 436, 2024
8Q8O
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BU of 8q8o by Molmil
PA14_16140 protein: the regulator of an operon involved in the biofilm formation in PA14 P. aeruginosa
分子名称: DUF2170 family protein, GLYCEROL, Tb-Xo4
著者Broutin, I, Phan, G, Girard, E.
登録日2023-08-18
公開日2024-02-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献BacA: a possible regulator that contributes to the biofilm formation of Pseudomonas aeruginosa .
Front Microbiol, 15, 2024
8Q89
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Crystal structure of Apis mellifera glutathione transferase delta 1 in a covalent dimeric state
分子名称: Glutathione S-transferase D1 isoform X1
著者Schwartz, M, Neiers, F.
登録日2023-08-18
公開日2023-10-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Structure-activity analysis suggests an olfactory function for the unique antennal delta glutathione transferase of Apis mellifera.
Febs Lett., 597, 2023
8Q7Y
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BU of 8q7y by Molmil
ESIBD structure of beta-galactosidase
分子名称: Beta-galactosidase
著者Esser, T, Boehning, J, Bharat, T.A.M, Rauschenbach, S.
登録日2023-08-17
公開日2024-01-10
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Cryo-EM of soft-landed beta-galactosidase: Gas-phase and native structures are remarkably similar.
Sci Adv, 10, 2024
8Q7S
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Crystal structure of the SARS-CoV-2 RBD (Wuhan) with neutralizing VHHs Ma6F06 and Re21H01
分子名称: 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, GLYCEROL, ...
著者Guttler, T, Aksu, M, Gorlich, D.
登録日2023-08-16
公開日2023-12-20
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Nanobodies to multiple spike variants and inhalation of nanobody-containing aerosols neutralize SARS-CoV-2 in cell culture and hamsters.
Antiviral Res., 221, 2023
8Q7J
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BU of 8q7j by Molmil
Conformations of macrocyclic peptides sampled by exact NOEs: models for cell-permeability
分子名称: CYCLOSPORIN A
著者Ruedisser, S.H, Matabaro, E, Sonderegger, L, Guentert, P, Kuenzler, M, Gossert, A.D.
登録日2023-08-16
公開日2023-12-06
最終更新日2024-01-03
実験手法SOLUTION NMR
主引用文献Conformations of Macrocyclic Peptides Sampled by Nuclear Magnetic Resonance: Models for Cell-Permeability.
J.Am.Chem.Soc., 145, 2023
8Q79
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BU of 8q79 by Molmil
Structure of mBaoJin at pH 6.5
分子名称: CHLORIDE ION, mBaoJin
著者Samygina, V.R, Subach, O.M, Vlaskina, A.V, Nikolaeva, A.Y, Borshchevsky, V, Qin, W, Subach, F.V.
登録日2023-08-15
公開日2023-12-27
最終更新日2024-04-24
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Bright and stable monomeric green fluorescent protein derived from StayGold.
Nat.Methods, 21, 2024
8Q76
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Copper-transporting ATPase HMA4 in E2P state with BeF
分子名称: Copper-transporting ATPase HMA4, MAGNESIUM ION
著者Guo, Z, Gourdon, P, Wang, K.
登録日2023-08-15
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Diverse roles of the metal binding domains and transport mechanism of copper transporting P-type ATPases.
Nat Commun, 15, 2024
8Q75
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Copper-transporting ATPase HMA4 in E2P state with AlF
分子名称: Copper-transporting ATPase HMA4, MAGNESIUM ION, TETRAFLUOROALUMINATE ION
著者Guo, Z, Gourdon, P, Wang, K.
登録日2023-08-15
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Diverse roles of the metal binding domains and transport mechanism of copper transporting P-type ATPases.
Nat Commun, 15, 2024
8Q74
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BU of 8q74 by Molmil
Copper-transporting ATPase HMA4 in E1 state with Cu
分子名称: COPPER (II) ION, Copper-transporting ATPase HMA4
著者Guo, Z, Gourdon, P, Wang, K.
登録日2023-08-15
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献Diverse roles of the metal binding domains and transport mechanism of copper transporting P-type ATPases.
Nat Commun, 15, 2024
8Q73
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Copper-transporting ATPase HMA4 in E1 state apo
分子名称: Copper-transporting ATPase HMA4
著者Guo, Z, Gourdon, P, Wang, K.
登録日2023-08-15
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Diverse roles of the metal binding domains and transport mechanism of copper transporting P-type ATPases.
Nat Commun, 15, 2024
8Q70
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tRNA pseudouridine synthase A homodimer
分子名称: CHLORIDE ION, MAGNESIUM ION, tRNA pseudouridine synthase A
著者Pacesa, M, Correia, B.E, Levy, E.D.
登録日2023-08-15
公開日2023-11-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献An atlas of protein homo-oligomerization across domains of life.
Cell, 187, 2024
8Q6Z
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Crystal structure of Cytochrome P450 GymB1 from Streptomyces flavidovirens
分子名称: GLYCEROL, GymB1, PROTOPORPHYRIN IX CONTAINING FE
著者Freytag, J, Kelm, T, Stehle, T, Zocher, G.
登録日2023-08-15
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Intramolecular Coupling and Nucleobase Transfer - How Cytochrome P450 Enzymes GymBx Establish Their Chemoselectivity
Chemcatchem, 16, 2024
8Q6M
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Human SOD1 low dose data collecton
分子名称: ACETATE ION, COPPER (II) ION, SULFATE ION, ...
著者Antonyuk, S.V, Hossain, A, Agar, J.N, Hasnain, S.S.
登録日2023-08-14
公開日2023-12-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS.
Plos Biol., 22, 2024
8Q6K
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Human IgD Fab in complex with an orthosteric inhibitor of Phl p 7
分子名称: 1,2-ETHANEDIOL, ACETATE ION, Human IgD Fab heavy chain, ...
著者Davies, A.M, Vester, S.K, McDonnell, J.M.
登録日2023-08-11
公開日2023-12-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Expanding the Anti-Phl p 7 Antibody Toolkit: An Anti-Idiotype Nanobody Inhibitor.
Antibodies, 12, 2023
8Q6F
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HUMAN PI4KIIIB IN COMPLEX WITH COVALENTLY BOUND INHIBITOR (COMPOUND 4)
分子名称: 1,2-ETHANEDIOL, 3-(3-fluorosulfonyloxy-4-methoxy-phenyl)-2,5-dimethyl-7-(pyridin-4-ylmethylamino)pyrazolo[1,5-a]pyrimidine, GLYCEROL, ...
著者Somers, D.O.
登録日2023-08-11
公開日2023-12-13
実験手法X-RAY DIFFRACTION (1.506 Å)
主引用文献Covalent targeting of non-cysteine residues in PI4KIII beta.
Rsc Chem Biol, 4, 2023

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件を2024-07-10に公開中

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