6YPH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6yph by Molmil](/molmil-images/mine/6yph) | |
3F6L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f6l by Molmil](/molmil-images/mine/3f6l) | Structure of the F4 fimbrial chaperone FaeE | 分子名称: | Chaperone protein faeE | 著者 | Van Molle, I, Moonens, K, Buts, L, Garcia-Pino, A, Wyns, L, De Greve, H, Bouckaert, J. | 登録日 | 2008-11-06 | 公開日 | 2009-05-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.801 Å) | 主引用文献 | The F4 fimbrial chaperone FaeE is stable as a monomer that does not require self-capping of its pilin-interactive surfaces Acta Crystallogr.,Sect.D, 65, 2009
|
|
6YGB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ygb by Molmil](/molmil-images/mine/6ygb) | Crystal structure of the NatC complex bound to CoA | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, COENZYME A, ... | 著者 | Grunwald, S, Hopf, L, Bock-Bierbaum, T, Lally, C.C, Spahn, C.M.T, Daumke, O. | 登録日 | 2020-03-27 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.451 Å) | 主引用文献 | Divergent architecture of the heterotrimeric NatC complex explains N-terminal acetylation of cognate substrates. Nat Commun, 11, 2020
|
|
6P4C
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6p4c by Molmil](/molmil-images/mine/6p4c) | HyHEL10 Fab carrying four heavy chain mutations (HyHEL10-4x): L4F, Y33H, S56N, and Y58F | 分子名称: | CHLORIDE ION, HyHEL10 Fab heavy chain, HyHEL10 Fab light chain | 著者 | Langley, D.B, Christ, D. | 登録日 | 2019-05-27 | 公開日 | 2020-05-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
3O74
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3o74 by Molmil](/molmil-images/mine/3o74) | Crystal structure of Cra transcriptional dual regulator from Pseudomonas putida | 分子名称: | Fructose transport system repressor FruR, GLYCEROL | 著者 | Chavarria, M, Santiago, C, Platero, R, Krell, T, Casasnovas, J.M, de Lorenzo, V. | 登録日 | 2010-07-30 | 公開日 | 2011-01-12 | 最終更新日 | 2011-12-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Fructose 1-phosphate is the preferred effector of the metabolic regulator Cra of Pseudomonas putida J.Biol.Chem., 286, 2011
|
|
3O7S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3o7s by Molmil](/molmil-images/mine/3o7s) | Crystal structure of Ru(p-cymene)/apo-Fr | 分子名称: | 1,2-ETHANEDIOL, 1-methyl-4-(1-methylethyl)benzene, CADMIUM ION, ... | 著者 | Takezawa, Y, Bockmann, P, Sugi, N, Wang, Z, Abe, S, Murakami, T, Hikage, T, Erker, G, Watanabe, Y, Kitagawa, S, Ueno, T. | 登録日 | 2010-07-31 | 公開日 | 2011-04-20 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Incorporation of organometallic Ru complexes into apo-ferritin cage. J.Chem.Soc.,Dalton Trans., 40, 2011
|
|
3FK0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3fk0 by Molmil](/molmil-images/mine/3fk0) | E. coli EPSP synthase (TIPS mutation) liganded with S3P | 分子名称: | 3-phosphoshikimate 1-carboxyvinyltransferase, FORMIC ACID, SHIKIMATE-3-PHOSPHATE | 著者 | Schonbrunn, E. | 登録日 | 2008-12-15 | 公開日 | 2009-02-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Basis of Glyphosate Resistance Resulting from the Double Mutation Thr97 -> Ile and Pro101 -> Ser in 5-Enolpyruvylshikimate-3-phosphate Synthase from Escherichia coli. J.Biol.Chem., 284, 2009
|
|
3F6Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f6q by Molmil](/molmil-images/mine/3f6q) | Crystal structure of integrin-linked kinase ankyrin repeat domain in complex with PINCH1 LIM1 domain | 分子名称: | IODIDE ION, Integrin-linked protein kinase, LIM and senescent cell antigen-like-containing domain protein 1, ... | 著者 | Chiswell, B.P, Calderwood, D.A, Boggon, T.J. | 登録日 | 2008-11-06 | 公開日 | 2008-12-02 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The structural basis of integrin-linked kinase-PINCH interactions. Proc.Natl.Acad.Sci.USA, 105, 2008
|
|
6YPT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ypt by Molmil](/molmil-images/mine/6ypt) | |
3NRC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nrc by Molmil](/molmil-images/mine/3nrc) | Crystal Structure of the Francisella tularensis enoyl-acyl carrier protein reductase (FabI) in complex with NAD+ and triclosan | 分子名称: | Enoyl-[acyl-carrier-protein] reductase (NADH), NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN | 著者 | Mehboob, S, Santarsiero, B.D, Truong, K, Johnson, M.E. | 登録日 | 2010-06-30 | 公開日 | 2010-11-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Structure of the Francisella tularensis enoyl-acyl carrier protein reductase (FabI) in complex with NAD(+) and triclosan. Acta Crystallogr.,Sect.F, 66, 2010
|
|
3EX7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ex7 by Molmil](/molmil-images/mine/3ex7) | |
3OAA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3oaa by Molmil](/molmil-images/mine/3oaa) | |
7Q8T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7q8t by Molmil](/molmil-images/mine/7q8t) | Crystal structure of NAMPT bound to ligand TSY535(compound 9a) | 分子名称: | Nicotinamide phosphoribosyltransferase, SULFATE ION, [(2~{R},3~{S},4~{R},5~{S})-3,4-bis(oxidanyl)-5-[4-[[[4-(phenylsulfonyl)phenyl]carbamoylamino]methyl]phenyl]oxolan-2-yl]methyl dihydrogen phosphate | 著者 | Kraemer, A, Tang, S, Butterworth, S, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2021-11-11 | 公開日 | 2021-11-24 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Chemistry-led investigations into the mode of action of NAMPT activators, resulting in the discovery of non-pyridyl class NAMPT activators. Acta Pharm Sin B, 13, 2023
|
|
6YLO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ylo by Molmil](/molmil-images/mine/6ylo) | mTurquoise2 - Directionality of Optical Properties of Fluorescent Proteins | 分子名称: | POTASSIUM ION, TETRAETHYLENE GLYCOL, mTurquoise2_C2221 | 著者 | Myskova, J, Rybakova, O, Brynda, J, Lazar, J. | 登録日 | 2020-04-07 | 公開日 | 2020-12-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Directionality of light absorption and emission in representative fluorescent proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
3NWI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nwi by Molmil](/molmil-images/mine/3nwi) | |
6YDJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ydj by Molmil](/molmil-images/mine/6ydj) | P146A variant of beta-phosphoglucomutase from Lactococcus lactis in complex with glucose 6-phosphate and trifluoromagnesate | 分子名称: | 1,2-ETHANEDIOL, 1,3-PROPANDIOL, 6-O-phosphono-beta-D-glucopyranose, ... | 著者 | Wood, H.P, Cruz-Navarrete, F.A, Baxter, N.J, Trevitt, C.R, Robertson, A.J, Dix, S.R, Hounslow, A.M, Cliff, M.J, Waltho, J.P. | 登録日 | 2020-03-20 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.04 Å) | 主引用文献 | Allomorphy as a mechanism of post-translational control of enzyme activity. Nat Commun, 11, 2020
|
|
6P4D
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6p4d by Molmil](/molmil-images/mine/6p4d) | Hen egg lysozyme (HEL) containing three point mutations (HEL3x): R21Q, R73E, and D101R | 分子名称: | CHLORIDE ION, GLYCEROL, Lysozyme C, ... | 著者 | Langley, D.B, Christ, D. | 登録日 | 2019-05-27 | 公開日 | 2020-05-27 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | Conformational diversity facilitates antibody mutation trajectories and discrimination between foreign and self-antigens. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6YDK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ydk by Molmil](/molmil-images/mine/6ydk) | Substrate-free P146A variant of beta-phosphoglucomutase from Lactococcus lactis | 分子名称: | Beta-phosphoglucomutase, MAGNESIUM ION | 著者 | Wood, H.P, Cruz-Navarrete, F.A, Baxter, N.J, Trevitt, C.R, Robertson, A.J, Dix, S.R, Hounslow, A.M, Cliff, M.J, Waltho, J.P. | 登録日 | 2020-03-20 | 公開日 | 2020-10-28 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Allomorphy as a mechanism of post-translational control of enzyme activity. Nat Commun, 11, 2020
|
|
3F0Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3f0q by Molmil](/molmil-images/mine/3f0q) | Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-Diamino-5-[3-(3-methoxy-5-(2,6-dimethylphenyl)phenyl)but-1-ynyl]-6-methylpyrimidine | 分子名称: | 5-[(3S)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Trimethoprim-sensitive dihydrofolate reductase | 著者 | Anderson, A.C, Frey, K.M, Liu, J, Lombardo, M.N. | 登録日 | 2008-10-25 | 公開日 | 2009-10-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Predicting resistance mutations using protein design algorithms. Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
7QGJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qgj by Molmil](/molmil-images/mine/7qgj) | Apo structure of BIR2 Domain of BIRC2 | 分子名称: | 1,2-ETHANEDIOL, Baculoviral IAP repeat-containing protein 2, ZINC ION | 著者 | Kraemer, A, Farges, F, Schwalm, M.P, Saxena, K, Preuss, F, Knapp, S, Structural Genomics Consortium (SGC) | 登録日 | 2021-12-08 | 公開日 | 2022-02-09 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Apo structure BIR2 Domain of BIRC2 To Be Published
|
|
3OAY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3oay by Molmil](/molmil-images/mine/3oay) | A non-self sugar mimic of the HIV glycan shield shows enhanced antigenicity | 分子名称: | Fab 2G12, heavy chain, light chain, ... | 著者 | Doores, K.J, Fulton, Z, Hong, V, Patel, M.K, Scanlan, C.N, Wormald, M.R, Finn, M.G, Burton, D.R, Wilson, I.A, Davis, B.G. | 登録日 | 2010-08-05 | 公開日 | 2011-01-12 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A nonself sugar mimic of the HIV glycan shield shows enhanced antigenicity. Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
3OBR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3obr by Molmil](/molmil-images/mine/3obr) | |
3EYH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3eyh by Molmil](/molmil-images/mine/3eyh) | Crystal structures of JAK1 and JAK2 inhibitor complexes | 分子名称: | 2-TERT-BUTYL-9-FLUORO-3,6-DIHYDRO-7H-BENZ[H]-IMIDAZ[4,5-F]ISOQUINOLINE-7-ONE, Tyrosine-protein kinase | 著者 | Williams, N.K, Bamert, R.S, Patell, O, Wang, C, Walden, P.M, Fantino, E. | 登録日 | 2008-10-20 | 公開日 | 2009-02-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Dissecting specificity in the Janus kinases: the structures of JAK-specific inhibitors complexed to the JAK1 and JAK2 protein tyrosine kinase domains. J.Mol.Biol., 387, 2009
|
|
6YPK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ypk by Molmil](/molmil-images/mine/6ypk) | |
6YHK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6yhk by Molmil](/molmil-images/mine/6yhk) | Crystal structure of full-length CNFy (C866S) from Yersinia pseudotuberculosis | 分子名称: | CHLORIDE ION, Cytotoxic necrotizing factor, SULFATE ION | 著者 | Lukat, P, Gazdag, E.M, Heidler, T.V, Blankenfeldt, W. | 登録日 | 2020-03-30 | 公開日 | 2020-12-30 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of bacterial cytotoxic necrotizing factor CNF Y reveals molecular building blocks for intoxication. Embo J., 40, 2021
|
|