6YPK

Crystal Structure of CK2alpha with GTP bound

Summary for 6YPK

Entry DOI	10.2210/pdb6ypk/pdb
Descriptor	Casein kinase II subunit alpha, GUANOSINE-5'-DIPHOSPHATE (3 entities in total)
Functional Keywords	selective atp competitive inhibitors, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	39474.59
Authors	Brear, P.,Hyvonen, M. (deposition date: 2020-04-16, release date: 2020-07-15, Last modification date: 2024-01-24)
Primary citation	Brear, P.,Ball, D.,Stott, K.,D'Arcy, S.,Hyvonen, M. Proposed Allosteric Inhibitors Bind to the ATP Site of CK2 alpha. J.Med.Chem., 63:12786-12798, 2020 Cited by PubMed: 33119282 DOI: 10.1021/acs.jmedchem.0c01173 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.79 Å)

Structure validation