8FR3
 
 | | E. coli EF-Tu in complex with KKL-55 | | 分子名称: | 3-chloro-N-(1-propyl-1H-tetrazol-5-yl)benzamide, Elongation factor Tu, GUANOSINE-5'-DIPHOSPHATE, ... | | 著者 | Nguyen, H.A, Kuzmishin Nagy, A.B, Dunham, C.M. | | 登録日 | 2023-01-06 | | 公開日 | 2023-09-20 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Antibiotic that inhibits trans -translation blocks binding of EF-Tu to tmRNA but not to tRNA.
Mbio, 14, 2023
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6LUL
 | | NMR structure and dynamics studies of yeast respiratory super-complex factor 2 in micelles | | 分子名称: | Respiratory supercomplex factor 2, mitochondrial | | 著者 | Zhou, S, Pontus, P, Peter, B, Maler, L, Adelroth, P. | | 登録日 | 2020-01-29 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | NMR Structure and Dynamics Studies of Yeast Respiratory Supercomplex Factor 2.
Structure, 29, 2021
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6IMF
 | | Crystal structure of TOXIN/ANTITOXIN complex | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cysteine-rich venom protein triflin, GLYCEROL, ... | | 著者 | Shioi, N, Tadokoro, T, Shioi, S, Hu, Y, Kurahara, L.H, Okabe, Y, Matsubara, H, Kita, S, Ose, T, Kuroki, K, Maenaka, K, Terada, S. | | 登録日 | 2018-10-22 | | 公開日 | 2018-12-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of the complex between venom toxin and serum inhibitor from Viperidae snake.
J. Biol. Chem., 294, 2019
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6S1V
 | | Crystal structure of dimeric M-PMV protease D26N mutant in complex with inhibitor | | 分子名称: | Gag-Pro-Pol polyprotein, PRO-0A1-VAL-PSA-ALA-MET-THR | | 著者 | Wosicki, S, Gilski, M, Jaskolski, M, Zabranska, H, Pichova, I. | | 登録日 | 2019-06-19 | | 公開日 | 2019-10-16 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Comparison of a retroviral protease in monomeric and dimeric states.
Acta Crystallogr D Struct Biol, 75, 2019
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8A8R
 | | Crystal structure of TEAD4 in complex with YAP peptide | | 分子名称: | Isoform 7 of Transcriptional coactivator YAP1, MYRISTIC ACID, Transcriptional enhancer factor TEF-3 | | 著者 | Scheufler, C, Kallen, J. | | 登録日 | 2022-06-23 | | 公開日 | 2022-12-28 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.696 Å) | | 主引用文献 | N-terminal beta-strand in YAP is critical for stronger binding to scalloped relative to TEAD transcription factor.
Protein Sci., 32, 2023
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6UTB
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6I9S
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8A8Q
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6ZOO
 | | Photosystem I reduced Plastocyanin Complex | | 分子名称: | (3R,3'R,6S)-4,5-DIDEHYDRO-5,6-DIHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, (3S,5R,6S,3'S,5'R,6'S)-5,6,5',6'-DIEPOXY-5,6,5',6'- TETRAHYDRO-BETA,BETA-CAROTENE-3,3'-DIOL, 1,2-DIACYL-GLYCEROL-3-SN-PHOSPHATE, ... | | 著者 | Nelson, N, Caspy, I, Shkolnisky, Y. | | 登録日 | 2020-07-07 | | 公開日 | 2021-06-16 | | 最終更新日 | 2021-07-07 | | 実験手法 | ELECTRON MICROSCOPY (2.74 Å) | | 主引用文献 | Structure of plant photosystem I-plastocyanin complex reveals strong hydrophobic interactions.
Biochem.J., 478, 2021
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6S1C
 | | P3221 crystal form of the Ctf18-1-8/Pol2(1-528) complex | | 分子名称: | Chromosome transmission fidelity protein 18, Chromosome transmission fidelity protein 8, DNA polymerase epsilon catalytic subunit A, ... | | 著者 | Grabarczyk, D.B. | | 登録日 | 2019-06-18 | | 公開日 | 2020-07-08 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (6.1 Å) | | 主引用文献 | Ctf18-RFC and DNA Pol ε form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication.
Nucleic Acids Res., 48, 2020
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8FYH
 | | G4 RNA-mediated PRC2 dimer | | 分子名称: | G4 RNA, Histone-binding protein RBBP4, Histone-lysine N-methyltransferase EZH2, ... | | 著者 | Song, J, Kasinath, V. | | 登録日 | 2023-01-26 | | 公開日 | 2023-10-04 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structural basis for inactivation of PRC2 by G-quadruplex RNA.
Science, 381, 2023
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1TTJ
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8QLP
 | | CryoEM structure of the RNA/DNA bound SPARTA (BabAgo/TIR-APAZ) tetrameric complex | | 分子名称: | DNA (5'-D(*AP*CP*TP*AP*AP*TP*AP*GP*AP*TP*TP*AP*GP*AP*GP*CP*CP*GP*TP*C)-3'), MAGNESIUM ION, RNA (5'-R(*AP*UP*GP*AP*CP*GP*GP*CP*UP*CP*UP*AP*AP*UP*CP*UP*AP*UP*UP*AP*GP*U)-3'), ... | | 著者 | Finocchio, G, Koopal, B, Potocnik, A, Heijstek, C, Jinek, M, Swarts, D. | | 登録日 | 2023-09-20 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA.
Nucleic Acids Res., 52, 2024
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8QOH
 | | Crystal structure of the kinetoplastid kinetochore protein KKT14 C-terminal domain from Apiculatamorpha spiralis | | 分子名称: | kinetochore protein KKT14 | | 著者 | Carter, W, Ballmer, D, Ishii, M, Ludzia, P, Akiyoshi, B. | | 登録日 | 2023-09-28 | | 公開日 | 2024-01-17 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Kinetoplastid kinetochore proteins KKT14-KKT15 are divergent Bub1/BubR1-Bub3 proteins.
Open Biology, 14, 2024
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6S5E
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8PLY
 | | Thioredoxin glutathione reductase of Schistosoma mansoni fragment screen hit 35. | | 分子名称: | 4-({[(thiophen-2-yl)methyl]amino}methyl)phenol, FLAVIN-ADENINE DINUCLEOTIDE, Thioredoxin glutathione reductase | | 著者 | Ribeiro, L, Montoya, B.O, Moreira-Filho, J.T, Bowyer, S, Verma, A, Neves, B.J, Owens, R.J, Andrade, C.H, Silva-Jr, F.P, Furnham, N. | | 登録日 | 2023-06-27 | | 公開日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Fragment library screening by X-ray crystallography and binding site analysis on thioredoxin glutathione reductase of Schistosoma mansoni.
Sci Rep, 14, 2024
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7KAA
 | | NMR solution structures of tirasemtiv drug bound to a fast skeletal troponin C-troponin I complex | | 分子名称: | 6-ethynyl-1-(pentan-3-yl)-1H-imidazo[4,5-b]pyrazin-2-ol, CALCIUM ION, Troponin C, ... | | 著者 | Mercier, P, Li, M.X, Hartman, J.J, Sykes, B.D. | | 登録日 | 2020-09-30 | | 公開日 | 2021-03-24 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural Basis of Tirasemtiv Activation of Fast Skeletal Muscle.
J.Med.Chem., 64, 2021
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8QLO
 | | CryoEM structure of the apo SPARTA (BabAgo/TIR-APAZ) complex | | 分子名称: | Short prokaryotic Argonaute, Toll/interleukin-1 receptor domain-containing protein | | 著者 | Finocchio, G, Koopal, B, Potocnik, A, Heijstek, C, Jinek, M, Swarts, D. | | 登録日 | 2023-09-20 | | 公開日 | 2024-01-31 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | | 主引用文献 | Target DNA-dependent activation mechanism of the prokaryotic immune system SPARTA.
Nucleic Acids Res., 52, 2024
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6USW
 | | CRYSTAL STRUCTURE OF HIV-1 LM/HS CLADE A/E CRF01 GP120 CORE IN COMPLEX WITH (S)-MCG-IV-210 | | 分子名称: | (3S)-N~1~-(2-aminoethyl)-N~3~-(4-chloro-3-fluorophenyl)piperidine-1,3-dicarboxamide, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Tolbert, W.D, Sherburn, R, Pazgier, M. | | 登録日 | 2019-10-28 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity and the CD4 Binding Site.
Mbio, 11, 2020
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8PM0
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8QMF
 | | Transketolase from Vibrio vulnificus in complex with thiamin pyrophosphate | | 分子名称: | 1,2-ETHANEDIOL, MAGNESIUM ION, NICKEL (II) ION, ... | | 著者 | Ballut, L, Georges, R.N, Octobre, G, Charmantray, F, Doumeche, B. | | 登録日 | 2023-09-22 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural determination and kinetic analysis of the transketolase from Vibrio vulnificus reveal unexpected cooperative behavior.
Protein Sci., 33, 2024
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6AM0
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5LFR
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6UPF
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5LIE
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