6AM0

Crystal structure of K. lactis Edc1-Dcp1-Dcp2-Edc3 decapping complex with synthetic cap substrate analog

Summary for 6AM0

• Entry DOI: 10.2210/pdb6am0/pdb
• Descriptor: KLLA0F23980p, KLLA0E01827p, KLLA0A01474p, ... (6 entities in total)
• Functional Keywords: mrna decay, decapping, nudix, nucleotide analog, translation
• Biological source: Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast); More
• Total number of polymer chains: 8
• Total formula weight: 129816.62

Authors

Mugridge, J.S.,Gross, J.D. (deposition date: 2017-08-08, release date: 2018-03-21, Last modification date: 2023-10-04)

• Primary citation: Mugridge, J.S.,Tibble, R.W.,Ziemniak, M.,Jemielity, J.,Gross, J.D.; Structure of the activated Edc1-Dcp1-Dcp2-Edc3 mRNA decapping complex with substrate analog poised for catalysis.; Nat Commun, 9:1152-1152, 2018; PubMed: 29559651; DOI: 10.1038/s41467-018-03536-x

Experimental method

X-RAY DIFFRACTION (2.84 Å)