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7UH9
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BU of 7uh9 by Molmil
NMR structure of the cNTnC-cTnI chimera bound to W8
分子名称: CALCIUM ION, N-(7-aminoheptyl)-5-chloronaphthalene-1-sulfonamide, Troponin C, ...
著者Cai, F, Kampourakis, T, Cockburn, K.T, Sykes, B.D.
登録日2022-03-26
公開日2022-06-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Drugging the Sarcomere, a Delicate Balance: Position of N-Terminal Charge of the Inhibitor W7.
Acs Chem.Biol., 17, 2022
7V1A
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BU of 7v1a by Molmil
Stapled TBS peptide from RIAM bound to talin R7R8 domains
分子名称: 1,2-ETHANEDIOL, ASP-ILE-ASP-GLN-MET-PHE-SER-THR-LEU-LEU-GLY-GLU-MK8-ASP-LEU-LEU-MK8-GLN-SER, Talin-1
著者Zhang, P, Gao, T, Wu, J.
登録日2022-05-11
公開日2023-06-14
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.845 Å)
主引用文献Inhibition of talin-induced integrin activation by a double-hit stapled peptide.
Structure, 31, 2023
7UHA
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BU of 7uha by Molmil
NMR structure of the cNTnC-cTnI chimera bound to W6
分子名称: CALCIUM ION, N-(5-aminopentyl)-5-chloronaphthalene-1-sulfonamide, Troponin C, ...
著者Cai, F, Kampourakis, T, Cockburn, K.T, Sykes, B.D.
登録日2022-03-26
公開日2022-06-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Drugging the Sarcomere, a Delicate Balance: Position of N-Terminal Charge of the Inhibitor W7.
Acs Chem.Biol., 17, 2022
4UEB
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BU of 4ueb by Molmil
Complex of D. melanogaster eIF4E with a designed 4E-binding protein (Form II)
分子名称: DESIGNED 4E-BP, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E
著者Peter, D, Weichenrieder, O.
登録日2014-12-16
公開日2015-02-25
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Molecular Architecture of 4E-BP Translational Inhibitors Bound to Eif4E.
Mol.Cell, 57, 2015
4ZRI
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BU of 4zri by Molmil
Crystal structure of Merlin-FERM and Lats2
分子名称: Merlin, Serine/threonine-protein kinase LATS2
著者Li, F, Zhou, H, Long, J, Shen, Y.
登録日2015-05-12
公開日2015-06-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
Cell Res., 25, 2015
1QDS
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BU of 1qds by Molmil
SUPERSTABLE E65Q MUTANT OF LEISHMANIA MEXICANA TRIOSEPHOSPHATE ISOMERASE (TIM)
分子名称: 2-PHOSPHOGLYCOLIC ACID, TRIOSEPHOSPHATE ISOMERASE
著者Lambeir, A.M, Backmann, J, Ruiz-Sanz, J, Filimonov, V, Nielsen, J.E, Vriend, G, Kursula, I, Norledge, B.V, Wierenga, R.K.
登録日1999-07-10
公開日2000-12-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The ionization of a buried glutamic acid is thermodynamically linked to the stability of Leishmania mexicana triose phosphate isomerase.
Eur.J.Biochem., 267, 2000
5OQT
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BU of 5oqt by Molmil
Crystal structure of a bacterial cationic amino acid transporter (CAT) homologue
分子名称: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, ACETATE ION, ALANINE, ...
著者Jungnickel, K.E.J, Newstead, S.
登録日2017-08-14
公開日2018-02-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structural basis for amino acid transport by the CAT family of SLC7 transporters.
Nat Commun, 9, 2018
7UKL
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BU of 7ukl by Molmil
Cryo-EM structure of Antibody 12-16 in complex with prefusion SARS-CoV-2 Spike glycoprotein
分子名称: 12-16 Fab Heavy Chain, 12-16 Fab Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Casner, R.G, Shapiro, L.
登録日2022-04-01
公開日2023-10-04
最終更新日2023-10-25
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking.
Immunity, 56, 2023
4U66
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BU of 4u66 by Molmil
Induced Dimer Structure of Methionine Sulfoxide Reductase U16C from Clostridium Oremlandii
分子名称: Peptide methionine sulfoxide reductase MsrA, SULFATE ION
著者Hwang, K.Y, Lee, E.H.
登録日2014-07-28
公開日2015-07-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Evidence for the Dimerization-Mediated Catalysis of Methionine Sulfoxide Reductase A from Clostridium oremlandii
Plos One, 10, 2015
4K2R
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BU of 4k2r by Molmil
Structural basis for activation of ZAP-70 by phosphorylation of the SH2-kinase linker
分子名称: MAGNESIUM ION, PHOSPHATE ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Yan, Q, Barros, T, Visperas, P.R, Deindl, S, Kadlecek, T.A, Weiss, A, Kuriyan, J.
登録日2013-04-09
公開日2013-05-08
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for Activation of ZAP-70 by Phosphorylation of the SH2-Kinase Linker.
Mol.Cell.Biol., 33, 2013
1HXD
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BU of 1hxd by Molmil
CRYSTAL STRUCTURE OF E. COLI BIOTIN REPRESSOR WITH BOUND BIOTIN
分子名称: BIOTIN, BIRA BIFUNCTIONAL PROTEIN
著者Kwon, K, Streaker, E.D, Ruparelia, S, Beckett, D.
登録日2001-01-12
公開日2001-05-30
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Corepressor-induced organization and assembly of the biotin repressor: a model for allosteric activation of a transcriptional regulator.
Proc.Natl.Acad.Sci.USA, 98, 2001
4ZHY
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BU of 4zhy by Molmil
Crystal structure of a bacterial signalling complex
分子名称: FORMIC ACID, SULFATE ION, YfiB, ...
著者Li, S, Li, T, Wang, Y, Bartlam, M.
登録日2015-04-27
公開日2016-04-27
実験手法X-RAY DIFFRACTION (1.969 Å)
主引用文献Structural insights into YfiR sequestering by YfiB in Pseudomonas aeruginosa PAO1
Sci Rep, 5, 2015
7VG9
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BU of 7vg9 by Molmil
Crystal structure of phosphotransbutyrylase from Clostridium acetobutylicum
分子名称: Phosphate butyryltransferase, SULFATE ION
著者Kim, S, Kim, K.-J.
登録日2021-09-15
公開日2021-10-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.91 Å)
主引用文献Crystal structure and molecular mechanism of phosphotransbutyrylase from Clostridium acetobutylicum .
J Microbiol Biotechnol., 31, 2021
2KNE
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BU of 2kne by Molmil
Calmodulin wraps around its binding domain in the plasma membrane CA2+ pump anchored by a novel 18-1 motif
分子名称: ATPase, Ca++ transporting, plasma membrane 4, ...
著者Juranic, N, Atanasova, E, Filoteo, A.G, Macura, S, Prendergast, F.G, Penniston, J.T, Strehler, E.E.
登録日2009-08-21
公開日2009-11-24
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Calmodulin wraps around its binding domain in the plasma membrane Ca2+ pump anchored by a novel 18-1 motif.
J.Biol.Chem., 285, 2010
4UNE
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BU of 4une by Molmil
Human insulin B26Phe mutant crystal structure
分子名称: INSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION
著者Zakova, L, Klevtikova, E, Lepsik, M, Collinsova, M, Watson, C.J, Turkenburg, J.P, Jiracek, J, Brzozowski, A.M.
登録日2014-05-28
公開日2014-10-15
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Human Insulin Analogues Modified at the B26 Site Reveal a Hormone Conformation that is Undetected in the Receptor Complex
Acta Crystallogr.,Sect.D, 70, 2014
2CVH
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BU of 2cvh by Molmil
Crystal structure of the RadB recombinase
分子名称: DNA repair and recombination protein radB
著者Akiba, T, Ishii, N, Rashid, N, Morikawa, M, Imanaka, T, Harata, K.
登録日2005-06-03
公開日2005-08-09
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of RadB recombinase from a hyperthermophilic archaeon, Thermococcus kodakaraensis KOD1: an implication for the formation of a near-7-fold helical assembly
Nucleic Acids Res., 33, 2005
7Y8W
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BU of 7y8w by Molmil
Crystal structure of DLC-1/SAO-1 complex
分子名称: Dynein light chain 1, cytoplasmic, GLYCEROL, ...
著者Yan, H, Zhao, C, Wei, Z, Yu, C.
登録日2022-06-24
公開日2023-07-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Interaction between DLC-1 and SAO-1 facilitates CED-4 translocation during apoptosis in the Caenorhabditis elegans germline.
Cell Death Discov, 8, 2022
2CVF
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BU of 2cvf by Molmil
Crystal structure of the RadB recombinase
分子名称: DNA repair and recombination protein radB
著者Akiba, T, Ishii, N, Rashid, N, Morikawa, M, Imanaka, T, Harata, K.
登録日2005-06-03
公開日2005-08-09
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of RadB recombinase from a hyperthermophilic archaeon, Thermococcus kodakaraensis KOD1: an implication for the formation of a near-7-fold helical assembly
Nucleic Acids Res., 33, 2005
3T6Q
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BU of 3t6q by Molmil
Crystal structure of mouse RP105/MD-1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CD180 antigen, ...
著者Ohto, U, Shimizu, T.
登録日2011-07-28
公開日2011-11-09
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structures of Mouse and Human RP105/MD-1 Complexes Reveal Unique Dimer Organization of the Toll-Like Receptor Family.
J.Mol.Biol., 413, 2011
3NMO
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BU of 3nmo by Molmil
Crystal structure of an engineered monomeric CLC-ec1 Cl-/H+ transporter
分子名称: CHLORIDE ION, H(+)/Cl(-) exchange transporter clcA
著者Robertson, J.L, Kolmakova-Partensky, L, Miller, C.
登録日2010-06-22
公開日2010-07-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Design, function and structure of a monomeric ClC transporter.
Nature, 468, 2010
4ZKT
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BU of 4zkt by Molmil
Crystal structure of the progenitor M complex of Clostridium botulinum type E neurotoxin
分子名称: Bontoxilysin A, Botulinum neurotoxin type E, nontoxic-nonhemagglutinin component, ...
著者Eswaramoorthy, S, Swaminathan, S.
登録日2015-04-30
公開日2015-12-23
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Molecular Assembly of Clostridium botulinum progenitor M complex of type E.
Sci Rep, 5, 2015
4ZRJ
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BU of 4zrj by Molmil
Structure of Merlin-FERM and CTD
分子名称: GLYCEROL, Merlin
著者Lin, Z, Li, F, Long, J, Shen, Y.
登録日2015-05-12
公開日2015-06-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Angiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
Cell Res., 25, 2015
2F60
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BU of 2f60 by Molmil
Crystal Structure of the Dihydrolipoamide Dehydrogenase (E3)-Binding Domain of Human E3-Binding Protein
分子名称: GLYCEROL, Pyruvate dehydrogenase protein X component
著者Brautigam, C.A, Chuang, J.L, Wynn, R.M, Tomchick, D.R, Machius, M, Chuang, D.T.
登録日2005-11-28
公開日2006-01-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural Insight into Interactions between Dihydrolipoamide Dehydrogenase (E3) and E3 Binding Protein of Human Pyruvate Dehydrogenase Complex.
Structure, 14, 2006
4Z9S
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BU of 4z9s by Molmil
Non-covalent assembly of monoubiquitin that mimics K11 poly-ubiquitin
分子名称: MALONIC ACID, THIOCYANATE ION, Ubiquitin-40S ribosomal protein S27a
著者Levin-Kravets, O, Prag, G.
登録日2015-04-11
公開日2015-07-29
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Tetrameric Assembly of Monoubiquitin Accurately Mimics the Lys11 Polyubiquitin Chain Structure.
Biochemistry, 54, 2015
4ZM9
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Crystal structure of circularly permuted human asparaginase-like protein 1
分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, BETA-MERCAPTOETHANOL, CITRATE ANION, ...
著者Li, W.Z, Zhang, Y.
登録日2015-05-02
公開日2016-02-17
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Intramolecular Cleavage of the hASRGL1 Homodimer Occurs in Two Stages.
Biochemistry, 55, 2016

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