8CG8
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![BU of 8cg8 by Molmil](/molmil-images/mine/8cg8) | Translocation intermediate 3 (TI-3) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | 登録日 | 2023-02-03 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | 主引用文献 | mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
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8CEH
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![BU of 8ceh by Molmil](/molmil-images/mine/8ceh) | Translocation intermediate 4 (TI-4) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | 著者 | Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. | 登録日 | 2023-02-01 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.05 Å) | 主引用文献 | mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
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8JZU
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![BU of 8jzu by Molmil](/molmil-images/mine/8jzu) | SLC15A4_TASL complex | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, TLR adapter,Green fluorescent protein, TSLAA-EGPF tag fusion protein | 著者 | Zhang, S.S, Chen, X.D, Xie, M. | 登録日 | 2023-07-06 | 公開日 | 2023-09-27 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | 主引用文献 | Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling. Nat Commun, 14, 2023
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7QLM
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8HGI
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![BU of 8hgi by Molmil](/molmil-images/mine/8hgi) | Crystal structure of VNAR aGFP14 in complex with GFP | 分子名称: | GFP, VNAR aGFP14, [2-(3-CARBAMOYL-1-IMINO-PROPYL)-4-(4-HYDROXY-BENZYLIDENE)-5-OXO-4,5-DIHYDRO-IMIDAZOL-1-YL]-ACETIC ACID | 著者 | Zheng, P, Zhu, C, Jin, T. | 登録日 | 2022-11-14 | 公開日 | 2023-09-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Selection, identification and crystal structure of shark-derived single-domain antibodies against a green fluorescent protein. Int.J.Biol.Macromol., 247, 2023
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8H0L
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![BU of 8h0l by Molmil](/molmil-images/mine/8h0l) | Sulfur binding domain of Hga complexed with phosphorothioated DNA | 分子名称: | DNA (5'-D(*CP*GP*AP*GP*(PST)P*TP*CP*GP*GP*C)-3'), DNA (5'-D(*GP*CP*CP*GP*AP*AP*CP*TP*CP*G)-3'), MAGNESIUM ION, ... | 著者 | Liu, G, He, X, Hu, W, Yang, B, Xiao, Q. | 登録日 | 2022-09-29 | 公開日 | 2023-09-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Characterization of a promiscuous DNA sulfur binding domain and application in site-directed RNA base editing. Nucleic Acids Res., 51, 2023
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8SMU
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![BU of 8smu by Molmil](/molmil-images/mine/8smu) | Integral fusion of the HtaA CR2 domain from Corynebacterium diphtheriae within EGFP | 分子名称: | CHLORIDE ION, GLYCEROL, HtaACR2 integral fusion within enhanced green fluorescent protein, ... | 著者 | Mahoney, B.J, Cascio, D, Clubb, R.T. | 登録日 | 2023-04-26 | 公開日 | 2023-09-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | Development and atomic structure of a new fluorescence-based sensor to probe heme transfer in bacterial pathogens. J.Inorg.Biochem., 249, 2023
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8T4S
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8DN5
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8DN2
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8DN3
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8DN4
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![BU of 8dn4 by Molmil](/molmil-images/mine/8dn4) | Cryo-EM structure of human Glycine Receptor alpha-1 beta heteromer, glycine-bound state3(desensitized state) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Glycine receptor subunit alpha-1, Glycine receptor subunit beta,Green fluorescent protein,Glycine receptor beta, ... | 著者 | Liu, X, Wang, W. | 登録日 | 2022-07-10 | 公開日 | 2023-10-11 | 最終更新日 | 2023-11-01 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Asymmetric gating of a human hetero-pentameric glycine receptor. Nat Commun, 14, 2023
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8A98
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![BU of 8a98 by Molmil](/molmil-images/mine/8a98) | CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT | 分子名称: | 40S ribosomal protein S12, 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, ... | 著者 | Rajan, K.S, Yonath, A, Bashan, A. | 登録日 | 2022-06-28 | 公開日 | 2023-10-11 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (2.46 Å) | 主引用文献 | Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
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7QLO
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7QLN
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8PPL
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![BU of 8ppl by Molmil](/molmil-images/mine/8ppl) | MERS-CoV Nsp1 bound to the human 43S pre-initiation complex | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N. | 登録日 | 2023-07-07 | 公開日 | 2023-10-18 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.65 Å) | 主引用文献 | Universal features of Nsp1-mediated translational shutdown by coronaviruses. Mol.Cell, 83, 2023
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8PPK
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![BU of 8ppk by Molmil](/molmil-images/mine/8ppk) | Bat-Hp-CoV Nsp1 and eIF1 bound to the human 40S small ribosomal subunit | 分子名称: | 18S rRNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | 著者 | Schubert, K, Karousis, E.D, Ban, I, Lapointe, C.P, Leibundgut, M, Baeumlin, E, Kummerant, E, Scaiola, A, Schoenhut, T, Ziegelmueller, J, Puglisi, J.D, Muehlemann, O, Ban, N. | 登録日 | 2023-07-07 | 公開日 | 2023-10-18 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.98 Å) | 主引用文献 | Universal features of Nsp1-mediated translational shutdown by coronaviruses. Mol.Cell, 83, 2023
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8THR
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![BU of 8thr by Molmil](/molmil-images/mine/8thr) | Structure of the human vesicular monoamine transporter 2 (VMAT2) bound to tetrabenazine in an occluded conformation | 分子名称: | (3S,5R,11bS)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-one, fluorescent protein mVenus,Synaptic vesicular amine transporter,GFP nano body,Synaptic vesicular amine transporter,Synaptic vesicular amine transporter | 著者 | Dalton, M.P, Coleman, J.A. | 登録日 | 2023-07-17 | 公開日 | 2023-10-25 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (3.12 Å) | 主引用文献 | Structural mechanisms for VMAT2 inhibition by tetrabenazine. Elife, 12, 2024
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8F1D
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![BU of 8f1d by Molmil](/molmil-images/mine/8f1d) | Voltage-gated potassium channel Kv3.1 apo | 分子名称: | CHOLESTEROL, POTASSIUM ION, Potassium voltage-gated channel subfamily C member 1, ... | 著者 | Chen, Y, Ishchenko, A. | 登録日 | 2022-11-04 | 公開日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (2.94 Å) | 主引用文献 | Identification and structural and biophysical characterization of a positive modulator of human Kv3.1 channels. Proc.Natl.Acad.Sci.USA, 120, 2023
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8F1C
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![BU of 8f1c by Molmil](/molmil-images/mine/8f1c) | Voltage-gated potassium channel Kv3.1 with novel positive modulator (9M)-9-{5-chloro-6-[(3,3-dimethyl-2,3-dihydro-1-benzofuran-4-yl)oxy]-4-methylpyridin-3-yl}-2-methyl-7,9-dihydro-8H-purin-8-one (compound 4) | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, (9M)-9-{5-chloro-6-[(3,3-dimethyl-2,3-dihydro-1-benzofuran-4-yl)oxy]-4-methylpyridin-3-yl}-2-methyl-7,9-dihydro-8H-purin-8-one, POTASSIUM ION, ... | 著者 | Chen, Y, Ishchenko, A. | 登録日 | 2022-11-04 | 公開日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Identification and structural and biophysical characterization of a positive modulator of human Kv3.1 channels. Proc.Natl.Acad.Sci.USA, 120, 2023
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8I4J
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8I4K
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![BU of 8i4k by Molmil](/molmil-images/mine/8i4k) | Structure of Azami Red1.0, a red fluorescent protein engineered from Azami Green | 分子名称: | Azami Red1.0, CALCIUM ION | 著者 | Otsubo, S, Takekawa, N, Imamura, H, Imada, K. | 登録日 | 2023-01-19 | 公開日 | 2023-11-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Red fluorescent proteins engineered from green fluorescent proteins. Proc.Natl.Acad.Sci.USA, 120, 2023
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7GFP
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![BU of 7gfp by Molmil](/molmil-images/mine/7gfp) | Group deposition SARS-CoV-2 main protease in complex with inhibitors from the COVID Moonshot -- Crystal Structure of SARS-CoV-2 main protease in complex with RAL-THA-6b94ceba-5 (Mpro-x11801) | 分子名称: | 2-[3-(acetamidomethyl)-5-chlorophenyl]-N-(4-methylpyridin-3-yl)acetamide, 3C-like proteinase, DIMETHYL SULFOXIDE | 著者 | Fearon, D, Aimon, A, Aschenbrenner, J.C, Balcomb, B.H, Bertram, F.K.R, Brandao-Neto, J, Dias, A, Douangamath, A, Dunnett, L, Godoy, A.S, Gorrie-Stone, T.J, Koekemoer, L, Krojer, T, Lithgo, R.M, Lukacik, P, Marples, P.G, Mikolajek, H, Nelson, E, Owen, C.D, Powell, A.J, Rangel, V.L, Skyner, R, Strain-Damerell, C.M, Thompson, W, Tomlinson, C.W.E, Wild, C, Walsh, M.A, von Delft, F. | 登録日 | 2023-08-11 | 公開日 | 2023-11-08 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.769 Å) | 主引用文献 | Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors. Science, 382, 2023
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8GW7
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![BU of 8gw7 by Molmil](/molmil-images/mine/8gw7) | AtSLAC1 6D mutant in open state | 分子名称: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein (Fragment) | 著者 | Lee, Y, Lee, S. | 登録日 | 2022-09-16 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model. Nat Commun, 14, 2023
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8GW6
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![BU of 8gw6 by Molmil](/molmil-images/mine/8gw6) | AtSLAC1 6D mutant in closed state | 分子名称: | CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, Guard cell S-type anion channel SLAC1,Green fluorescent protein (Fragment) | 著者 | Lee, Y, Lee, S. | 登録日 | 2022-09-16 | 公開日 | 2023-11-15 | 最終更新日 | 2023-11-29 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Cryo-EM structures of the plant anion channel SLAC1 from Arabidopsis thaliana suggest a combined activation model. Nat Commun, 14, 2023
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