7YWX
 
 | | Structure of the human CCAN CENP-A alpha-satellite complex | | 分子名称: | Centromere protein C, Centromere protein H, Centromere protein I, ... | | 著者 | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | | 登録日 | 2022-02-14 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (12 Å) | | 主引用文献 | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
|
|
7YYH
 | | Structure of the human CCANdeltaT CENP-A alpha-satellite complex | | 分子名称: | Centromere protein C, Centromere protein H, Centromere protein I, ... | | 著者 | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | | 登録日 | 2022-02-17 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (8.9 Å) | | 主引用文献 | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
|
|
6R84
 | | Yeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state with Arb1) | | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R. | | 登録日 | 2019-03-31 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis.
Nature, 570, 2019
|
|
2WOM
 | | Crystal Structure of UK-453061 bound to HIV-1 Reverse Transcriptase (K103N). | | 分子名称: | 5-{[3,5-diethyl-1-(2-hydroxyethyl)-1H-pyrazol-4-yl]oxy}benzene-1,3-dicarbonitrile, HIV-1 REVERSE TRANSCRIPTASE | | 著者 | Phillips, C, Irving, S.L, Knoechel, T, Ringrose, H. | | 登録日 | 2009-07-27 | | 公開日 | 2010-08-11 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Lersivirine, a nonnucleoside reverse transcriptase inhibitor with activity against drug-resistant human immunodeficiency virus type 1.
Antimicrob. Agents Chemother., 54, 2010
|
|
4IXN
 | | Crystal Structure of Zn(II)-bound E37A,C66A,C67A triple mutant YjiA GTPase | | 分子名称: | SULFATE ION, Uncharacterized GTP-binding protein YjiA, ZINC ION | | 著者 | Jost, M, Drennan, C.L. | | 登録日 | 2013-01-26 | | 公開日 | 2013-02-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Metal binding properties of Escherichia coli YjiA, a member of the metal homeostasis-associated COG0523 family of GTPases.
Biochemistry, 52, 2013
|
|
8GRQ
 | | Cryo-EM structure of BRCA1/BARD1 bound to H2AK127-UbcH5c-Ub nucleosome | | 分子名称: | BRCA1-associated RING domain protein 1, Breast cancer type 1 susceptibility protein, DNA (147-MER), ... | | 著者 | Ai, H.S, Zebin, T, Zhiheng, D, Jiakun, T, Liying, Z, Jia-Bin, L, Man, P, Liu, L. | | 登録日 | 2022-09-02 | | 公開日 | 2023-04-12 | | 最終更新日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | | 主引用文献 | Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination.
Chem, 2023
|
|
4IXM
 | | Crystal structure of Zn(II)-bound YjiA GTPase from E. coli | | 分子名称: | SULFATE ION, Uncharacterized GTP-binding protein YjiA, ZINC ION | | 著者 | Jost, M, Ryan, K.S, Turo, K.E, Drennan, C.L. | | 登録日 | 2013-01-26 | | 公開日 | 2013-02-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Metal binding properties of Escherichia coli YjiA, a member of the metal homeostasis-associated COG0523 family of GTPases.
Biochemistry, 52, 2013
|
|
6WG5
 | | Human ectonucleoside triphosphate diphosphohydrolase 4 (ENTPD4, NTPDase 4) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ectonucleoside triphosphate diphosphohydrolase 4 | | 著者 | Gorelik, A, Labriola, J.M, Illes, K, Nagar, B. | | 登録日 | 2020-04-04 | | 公開日 | 2020-08-12 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of the nucleotide-metabolizing enzyme NTPDase4.
Protein Sci., 29, 2020
|
|
7SB7
 | | Crystal structure of T. brucei hypoxanthine guanine phosphoribosyltransferase in complex with (4S,7S)-7-hydroxy-4-((guanin-9-yl)methyl)-2,5-dioxaheptan-1,7-diphosphonate | | 分子名称: | ({(2S)-3-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-2-[(2S)-2-hydroxy-2-phosphonoethoxy]propoxy}methyl)phosphonic acid, Hypoxanthine-guanine phosphoribosyltransferase | | 著者 | Guddat, L.W, Keough, D.T. | | 登録日 | 2021-09-24 | | 公開日 | 2022-03-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.64716625 Å) | | 主引用文献 | Stereo-Defined Acyclic Nucleoside Phosphonates are Selective and Potent Inhibitors of Parasite 6-Oxopurine Phosphoribosyltransferases.
J.Med.Chem., 65, 2022
|
|
6I8T
 | |
7Z1J
 | | Escherichia coli periplasmic phytase AppA, complex with phosphate | | 分子名称: | Acidphosphatase, MAGNESIUM ION, NICKEL (II) ION, ... | | 著者 | Acquistapace, I.M, Brearley, C.A, Hemmings, A.M. | | 登録日 | 2022-02-24 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.
Int J Mol Sci, 23, 2022
|
|
7Z2Y
 | | Escherichia coli periplasmic phytase AppA T305E mutant, complex with myo-inositol hexakissulfate | | 分子名称: | Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, NICKEL (II) ION | | 著者 | Acquistapace, I.M, Brearley, C.A, Hemmings, A.M. | | 登録日 | 2022-03-01 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.
Int J Mol Sci, 23, 2022
|
|
7Z2S
 | | Escherichia coli periplasmic phytase AppA, complex with myo-inositol hexakissulfate | | 分子名称: | Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, NICKEL (II) ION, ... | | 著者 | Acquistapace, I.M, Brearley, C.A, Hemmings, A.M. | | 登録日 | 2022-02-28 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.
Int J Mol Sci, 23, 2022
|
|
7Z2W
 | | Escherichia coli periplasmic phytase AppA D304A,T305E mutant, complex with myo-inositol hexakissulfate | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, ... | | 著者 | Acquistapace, I.M, Brearley, C.A, Hemmings, A.M. | | 登録日 | 2022-03-01 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.42 Å) | | 主引用文献 | Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.
Int J Mol Sci, 23, 2022
|
|
7Z32
 | | Escherichia coli periplasmic phytase AppA D304A mutant, phosphohistidine intermediate | | 分子名称: | Acidphosphatase, NICKEL (II) ION | | 著者 | Acquistapace, I.M, Brearley, C.A, Hemmings, A.M. | | 登録日 | 2022-03-01 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.
Int J Mol Sci, 23, 2022
|
|
7Z2T
 | | Escherichia coli periplasmic phytase AppA D304A mutant, complex with myo-inositol hexakissulfate | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, ... | | 著者 | Acquistapace, I.M, Brearley, C.A, Hemmings, A.M. | | 登録日 | 2022-02-28 | | 公開日 | 2022-03-16 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | | 主引用文献 | Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.
Int J Mol Sci, 23, 2022
|
|
6I8M
 | |
6ISW
 | | Structure of human telomeric DNA with 5-selenophene-modified deoxyuridine at residue 12 | | 分子名称: | DNA (22-MER), POTASSIUM ION | | 著者 | Saikrishnan, K, Nuthanakanti, A, Srivatsan, S.G, Ahmad, I. | | 登録日 | 2018-11-19 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Probing G-quadruplex topologies and recognition concurrently in real time and 3D using a dual-app nucleoside probe.
Nucleic Acids Res., 47, 2019
|
|
7Z3V
 | | Escherichia coli periplasmic phytase AppA D304E mutant, complex with myo-inositol hexakissulfate | | 分子名称: | Acidphosphatase, D-MYO-INOSITOL-HEXASULPHATE, POTASSIUM ION | | 著者 | Acquistapace, I.M, Brearley, C.A, Hemmings, A.M. | | 登録日 | 2022-03-02 | | 公開日 | 2022-06-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Insights to the Structural Basis for the Stereospecificity of the Escherichia coli Phytase, AppA.
Int J Mol Sci, 23, 2022
|
|
6IP7
 | | Structure of human telomeric DNA with 5-Selenophene-modified deoxyuridine at residue 11 | | 分子名称: | DNA (22-MER), POTASSIUM ION | | 著者 | Saikrishnan, K, Nuthanakanti, A, Srivatsan, S.G, Ahmad, I. | | 登録日 | 2018-11-02 | | 公開日 | 2019-05-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Probing G-quadruplex topologies and recognition concurrently in real time and 3D using a dual-app nucleoside probe.
Nucleic Acids Res., 47, 2019
|
|
4R25
 | | Structure of B. subtilis GlnK | | 分子名称: | Nitrogen regulatory PII-like protein, ZINC ION | | 著者 | Schumacher, M.A. | | 登録日 | 2014-08-08 | | 公開日 | 2015-03-04 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5193 Å) | | 主引用文献 | Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
Genes Dev., 29, 2015
|
|
4WTV
 | | Crystal structure of the phosphatidylinositol 4-kinase IIbeta | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Phosphatidylinositol 4-kinase type 2-beta,Endolysin,Phosphatidylinositol 4-kinase type 2-beta | | 著者 | Klima, M, Baumlova, A, Chalupska, D, Boura, E. | | 登録日 | 2014-10-30 | | 公開日 | 2015-07-15 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | The high-resolution crystal structure of phosphatidylinositol 4-kinase II beta and the crystal structure of phosphatidylinositol 4-kinase II alpha containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design.
Acta Crystallogr.,Sect.D, 71, 2015
|
|
4R22
 | | TnrA-DNA complex | | 分子名称: | DNA (5'-D(*CP*GP*TP*GP*TP*AP*AP*GP*GP*AP*AP*TP*TP*CP*TP*GP*AP*CP*AP*CP*G)-3'), HTH-type transcriptional regulator TnrA | | 著者 | Schumacher, M.A. | | 登録日 | 2014-08-08 | | 公開日 | 2015-03-04 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
Genes Dev., 29, 2015
|
|
4RX6
 | | Structure of B. subtilis GlnK-ATP complex to 2.6 Angstrom | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Nitrogen regulatory PII-like protein | | 著者 | Schumacher, M.A, Cuthbert, B, Tonthat, N, Chinnam, N.G, Whitfill, T. | | 登録日 | 2014-12-09 | | 公開日 | 2015-12-30 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5994 Å) | | 主引用文献 | Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
Genes Dev., 29, 2015
|
|
2ZD1
 | | Crystal Structure of HIV-1 Reverse Transcriptase (RT) in Complex with TMC278 (Rilpivirine), A Non-nucleoside RT Inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, Reverse transcriptase/ribonuclease H, ... | | 著者 | Das, K, Bauman, J.D, Clark Jr, A.D, Shatkin, A.J, Arnold, E. | | 登録日 | 2007-11-16 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: Strategic flexibility explains potency against resistance mutations.
Proc.Natl.Acad.Sci.Usa, 105, 2008
|
|
