4WTV

Crystal structure of the phosphatidylinositol 4-kinase IIbeta

Summary for 4WTV

Entry DOI	10.2210/pdb4wtv/pdb
Descriptor	Phosphatidylinositol 4-kinase type 2-beta,Endolysin,Phosphatidylinositol 4-kinase type 2-beta, ADENOSINE-5'-TRIPHOSPHATE (3 entities in total)
Functional Keywords	lipid kinase, phosphatidyl inositol, transferase, hydrolase
Biological source	Homo sapiens (Human) More
Cellular location	Cytoplasm: Q8TCG2
Total number of polymer chains	2
Total formula weight	119750.16
Authors	Klima, M.,Baumlova, A.,Chalupska, D.,Boura, E. (deposition date: 2014-10-30, release date: 2015-07-15, Last modification date: 2024-01-10)
Primary citation	Klima, M.,Baumlova, A.,Chalupska, D.,Hrebabecky, H.,Dejmek, M.,Nencka, R.,Boura, E. The high-resolution crystal structure of phosphatidylinositol 4-kinase II beta and the crystal structure of phosphatidylinositol 4-kinase II alpha containing a nucleoside analogue provide a structural basis for isoform-specific inhibitor design. Acta Crystallogr.,Sect.D, 71:1555-1563, 2015 Cited by PubMed: 26143926 DOI: 10.1107/S1399004715009505 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation