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2RS1	STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES 分子名称: 5-(7-(5-HYDRO-4-METHYL-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ... 著者 Badger, J, Smith, T.J, Rossmann, M.G. 登録日 1988-10-03 公開日 1990-01-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses. Proteins, 6, 1989
5IFC	Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4720 1-(4-bromophenyl)-1H-imidazole 分子名称: 1-(4-bromophenyl)-1H-imidazole, DIMETHYL SULFOXIDE, Polymerase acidic protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-02-25 公開日 2017-02-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA To Be Published
1ONB	Solution structure of an engineered arginine-rich subdomain 2 of the hepatitis C virus NS3 RNA helicase 分子名称: helicase NS3 著者 Liu, D, Wang, Y.S, Gesell, J.J, Wyss, D.F. 登録日 2003-02-27 公開日 2003-03-11 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution structure and backbone dynamics of an engineered arginine-rich subdomain 2 of the hepatitis C virus NS3 RNA helicase J.Mol.Biol., 314, 2001
1UZG	CRYSTAL STRUCTURE OF THE DENGUE TYPE 3 VIRUS ENVELOPE PROTEIN 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MAJOR ENVELOPE PROTEIN E, alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Modis, Y, Harrison, S.C. 登録日 2004-03-11 公開日 2005-03-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Variable Surface Epitopes in the Crystal Structure of Dengue Virus Type 3 Envelope Glycoprotein J.Virol., 79, 2005
5IFB	Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4719 5-chloro-2-(1H-imidazol-1-yl)aniline 分子名称: 5-chloro-2-(1H-imidazol-1-yl)aniline, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-02-25 公開日 2017-02-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA To Be Published
5IF8	Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-2643 5-[(4-chlorophenyl)methyl]-1,3,4-oxadiazol-2-amine 分子名称: 1,2-ETHANEDIOL, 5-[(4-chlorophenyl)methyl]-1,3,4-oxadiazol-2-amine, CHLORIDE ION, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-02-25 公開日 2017-02-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA To Be Published
5IF7	Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-279 N-[(4-chlorophenyl)methyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine 分子名称: DIMETHYL SULFOXIDE, N-[(4-chlorophenyl)methyl]-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Polymerase acidic protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-02-25 公開日 2017-02-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA To Be Published
5FFM	Yellow fever virus helicase 分子名称: Serine protease NS3 著者 Smith, J.L. 登録日 2015-12-18 公開日 2015-12-30 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure of the Flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing. J. Virol., 79, 2005
1CU1	CRYSTAL STRUCTURE OF AN ENZYME COMPLEX FROM HEPATITIS C VIRUS 分子名称: PHOSPHATE ION, PROTEIN (PROTEASE/HELICASE NS3), ZINC ION 著者 Yao, N, Weber, P.C. 登録日 1999-08-20 公開日 2000-08-23 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase. Structure Fold.Des., 7, 1999
5IEQ	Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-747 1-(4-chlorophenyl)-1H-imidazole 分子名称: 1-(4-CHLOROPHENYL)-1H-IMIDAZOLE, DIMETHYL SULFOXIDE, Polymerase acidic protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-02-25 公開日 2017-02-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA To Be Published
5IF2	Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to fragment hit EBSI-576 (5,6-dichloro-1H-1,3-benzodiazol-2-yl)methanol 分子名称: (5,6-dichloro-1H-benzimidazol-2-yl)methanol, CHLORIDE ION, DIMETHYL SULFOXIDE, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-02-25 公開日 2017-02-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA To Be Published
5IFD	Crystal structure of polymerase acid protein (PA) from Influenza A virus, WILSON-SMITH/1933 (H1N1) bound to follow on fragment EBSI-4721 1-(4-fluorophenyl)-1H-imidazole 分子名称: 1-(4-fluorophenyl)-1H-imidazole, DIMETHYL SULFOXIDE, Polymerase acidic protein 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-02-25 公開日 2017-02-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 Fragment screening by STD NMR identifies novel site binders against influenza A virus polymerase PA To Be Published
2R04	STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES 分子名称: 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ... 著者 Badger, J, Smith, T.J, Rossmann, M.G. 登録日 1988-10-03 公開日 1990-01-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses. Proteins, 6, 1989
2R07	STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES 分子名称: 5-(5-(6-CHLORO-4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ... 著者 Badger, J, Smith, T.J, Rossmann, M.G. 登録日 1988-10-03 公開日 1990-01-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses. Proteins, 6, 1989
2R06	STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES 分子名称: 5-(5-(4-(4,5-DIHYDRO-2-OXAZOLY)PHENOXY)PENTYL)-3-METHYL ISOXAZOLE, HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP1), HUMAN RHINOVIRUS 14 COAT PROTEIN (SUBUNIT VP2), ... 著者 Badger, J, Smith, T.J, Rossmann, M.G. 登録日 1988-10-03 公開日 1990-01-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural analysis of antiviral agents that interact with the capsid of human rhinoviruses. Proteins, 6, 1989
1BT7	THE SOLUTION NMR STRUCTURE OF THE N-TERMINAL PROTEASE DOMAIN OF THE HEPATITIS C VIRUS (HCV) NS3-PROTEIN, FROM BK STRAIN, 20 STRUCTURES 分子名称: NS3 SERINE PROTEASE, ZINC ION 著者 Barbato, G, Cicero, D.O, Nardi, M.C, Steinkuhler, C, Cortese, R, De Francesco, R, Bazzo, R. 登録日 1998-09-01 公開日 1999-06-22 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 The solution structure of the N-terminal proteinase domain of the hepatitis C virus (HCV) NS3 protein provides new insights into its activation and catalytic mechanism. J.Mol.Biol., 289, 1999
1ND3	The structure of HRV16, when complexed with pleconaril, an antiviral compound 分子名称: 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, ZINC ION, coat protein VP1, ... 著者 Zhang, Y, Simpson, A.A, Bator, C.M, Chakravarty, S, Pevear, D.C, Skochko, G.A, Tull, T.M, Diana, G, Rossmann, M.G. 登録日 2002-12-06 公開日 2003-12-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds J.Virol., 78, 2004
1ND2	The structure of Rhinovirus 16 分子名称: MYRISTIC ACID, ZINC ION, coat protein VP1, ... 著者 Zhang, Y, Simpson, A.A, Bator, C.M, Chakravarty, S, Pevear, D.C, Skochko, G.A, Tull, T.M, Diana, G, Rossmann, M.G. 登録日 2002-12-06 公開日 2003-12-16 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds J.Virol., 78, 2004
1NCR	The structure of Rhinovirus 16 when complexed with pleconaril, an antiviral compound 分子名称: 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, MYRISTIC ACID, ZINC ION, ... 著者 Zhang, Y, Simpson, A.A, Bator, C.M, Chakravarty, S, Pevear, D.C, Skochko, G.A, Tull, T.M, Diana, G, Rossmann, M.G. 登録日 2002-12-05 公開日 2003-12-16 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds J.Virol., 78, 2004
4J1V	Functional and structural studies of MOBKL1B, a Salvador/Warts/Hippo tumor suppressor pathway, in HCV replication 分子名称: MOB kinase activator 1A, NS5A domain II peptide, ZINC ION 著者 Chung, H.-Y, Gu, M, Rice, C.M. 登録日 2013-02-02 公開日 2014-08-06 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Seed Sequence-Matched Controls Reveal Limitations of Small Interfering RNA Knockdown in Functional and Structural Studies of Hepatitis C Virus NS5A-MOBKL1B Interaction. J.Virol., 88, 2014
5IYT	Complex structure of EV-B93 main protease 3C with N-Ethyl 4-((1-cycloheptyl-1,2-dihydropyrazol-3-one-5-yl)-amino)-4-oxo-2Z-butenamide 分子名称: EV-B93 main protease 3C, N-Ethyl 4-((1-cycloheptyl-1,2-dihydropyrazol-3-one-5-yl)-amino)-4-oxo-butanamide 著者 Kaczmarska, Z, Becker, D, Rademann, J, Coll, M. 登録日 2016-03-24 公開日 2016-10-05 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Irreversible inhibitors of the 3C protease of Coxsackie virus through templated assembly of protein-binding fragments. Nat Commun, 7, 2016
1PIV	BINDING OF THE ANTIVIRAL DRUG WIN51711 TO THE SABIN STRAIN OF TYPE 3 POLIOVIRUS: STRUCTURAL COMPARISON WITH DRUG BINDING IN RHINOVIRUS 14 分子名称: 5-(7-(4-(4,5-DIHYDRO-2-OXAZOLYL)PHENOXY)HEPTYL)-3-METHYL ISOXAZOLE, MYRISTIC ACID, POLIOVIRUS TYPE 3 (SUBUNIT VP1), ... 著者 Hiremath, C.N, Grant, R.A, Filman, D.J, Hogle, J.M. 登録日 1995-02-02 公開日 1995-06-03 最終更新日 2024-06-05 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Binding of the antiviral drug WIN51711 to the sabin strain of type 3 poliovirus: structural comparison with drug binding in rhinovirus 14. Acta Crystallogr.,Sect.D, 51, 1995
1ZH1	Structure of the zinc-binding domain of HCV NS5A 分子名称: ZINC ION, non-structural polyprotein 著者 Tellinghuisen, T.L, Marcotrigiano, J, Rice, C.M. 登録日 2005-04-22 公開日 2005-05-24 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase. Nature, 435, 2005
3RVB	The structure of HCV NS3 helicase (Heli-80) bound with inhibitor ITMN-3479 分子名称: CHLORIDE ION, MAGNESIUM ION, RNA helicase, ... 著者 Mather, O, Cheng, R, Schonfield, D, Barker, J. 登録日 2011-05-06 公開日 2014-09-24 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The structure of HCV NS3 helicase with inhibitor ITMN-3479 To be Published
3IYC	Poliovirus late RNA-release intermediate 分子名称: Capsid protein VP1, Capsid protein VP2, Genome polyprotein, ... 著者 Levy, H.C, Bostina, M, Filman, D.J, Hogle, J.M. 登録日 2009-07-21 公開日 2010-03-16 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (10 Å) 主引用文献 Catching a virus in the act of RNA release: a novel poliovirus uncoating intermediate characterized by cryo-electron microscopy. J.Virol., 84, 2010

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