6R84
 
 | | Yeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state with Arb1) | | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R. | | 登録日 | 2019-03-31 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-11-20 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis.
Nature, 570, 2019
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6R86
 | | Yeast Vms1-60S ribosomal subunit complex (post-state) | | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R. | | 登録日 | 2019-03-31 | | 公開日 | 2019-07-31 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis.
Nature, 570, 2019
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7CRQ
 | | NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (2:1 binding mode) | | 分子名称: | DNA (168-MER), Histone H2A, Histone H2B, ... | | 著者 | Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z. | | 登録日 | 2020-08-14 | | 公開日 | 2020-10-21 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | | 主引用文献 | Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.
Nature, 590, 2021
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7CRP
 | | NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (1:1 binding mode) | | 分子名称: | DNA (168-MER), Histone H2A, Histone H2B, ... | | 著者 | Li, W, Tian, W, Yuan, G, Deng, P, Gozani, O, Patel, D, Wang, Z. | | 登録日 | 2020-08-14 | | 公開日 | 2020-10-21 | | 最終更新日 | 2025-07-02 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases.
Nature, 590, 2021
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7XVM
 | | Crystal Structure of Nucleosome-H5 Linker Histone Assembly (sticky-169a DNA fragment) | | 分子名称: | CALCIUM ION, CHLORIDE ION, DNA (169-MER), ... | | 著者 | Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A. | | 登録日 | 2022-05-24 | | 公開日 | 2023-05-24 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.84 Å) | | 主引用文献 | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment)
To Be Published
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7XX5
 | | Crystal Structure of Nucleosome-H1.3 Linker Histone Assembly (sticky-169a DNA fragment) | | 分子名称: | CALCIUM ION, DNA (169-MER), Histone H1.3, ... | | 著者 | Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A. | | 登録日 | 2022-05-28 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | | 主引用文献 | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment)
To Be Published
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7SEK
 | | Solution structure of the zinc finger domain of murine MetAP1, complexed with ZNG N-terminal peptide | | 分子名称: | COBW domain-containing protein 1,Methionine aminopeptidase 1 fusion, ZINC ION | | 著者 | Edmonds, K.A, Jordan, M.R, Thalluri, K, Wu, H, Di Marchi, R, Giedroc, D.P. | | 登録日 | 2021-09-30 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Zn-regulated GTPase metalloprotein activator 1 modulates vertebrate zinc homeostasis.
Cell, 185, 2022
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7VVY
 | | TRA module of NuA4 | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Actin, Actin-related protein 4, ... | | 著者 | Chen, Z, Qu, K. | | 登録日 | 2021-11-09 | | 公開日 | 2022-08-10 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structure of the NuA4 acetyltransferase complex bound to the nucleosome.
Nature, 610, 2022
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8Z50
 | | Crystal structure of the ASF1-H3T-H4 complex | | 分子名称: | Histone H3.1t, Histone H4, Histone chaperone ASF1A | | 著者 | Xu, L. | | 登録日 | 2024-04-18 | | 公開日 | 2024-07-03 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural insights into instability of the nucleosome driven by histone variant H3T.
Biochem.Biophys.Res.Commun., 727, 2024
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4R4E
 | | Structure of GlnR-DNA complex | | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, DNA (5'-D(*AP*TP*TP*CP*TP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*AP*GP*TP*A)-3'), ... | | 著者 | Schumacher, M.A. | | 登録日 | 2014-08-19 | | 公開日 | 2015-03-04 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
Genes Dev., 29, 2015
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7EPU
 | | Crystal structure of HsALC1 | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Chromodomain-helicase-DNA-binding protein 1-like, MAGNESIUM ION, ... | | 著者 | Wang, L, Chen, K.J. | | 登録日 | 2021-04-27 | | 公開日 | 2021-07-14 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis of ALC1/CHD1L autoinhibition and the mechanism of activation by the nucleosome.
Nat Commun, 12, 2021
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2ZE2
 | | Crystal structure of L100I/K103N mutant HIV-1 reverse transcriptase (RT) in complex with TMC278 (rilpivirine), a non-nucleoside RT inhibitor | | 分子名称: | 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, Reverse transcriptase/ribonuclease H, p51 RT | | 著者 | Das, K, Bauman, J.D, Clark Jr, A.D, Shatkin, A.J, Arnold, E. | | 登録日 | 2007-12-05 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: Strategic flexibility explains potency against resistance mutations.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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7XX6
 | | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment) | | 分子名称: | CALCIUM ION, DNA (169-MER), Histone H1.0, ... | | 著者 | Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A. | | 登録日 | 2022-05-28 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.39 Å) | | 主引用文献 | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169a DNA fragment)
To Be Published
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7XVL
 | | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169an DNA fragment) | | 分子名称: | DNA (169-MER), Histone H1.0, Histone H2A type 1-B/E, ... | | 著者 | Adhireksan, Z, Qiuye, B, Lee, P.L, Sharma, D, Padavattan, S, Davey, C.A. | | 登録日 | 2022-05-24 | | 公開日 | 2023-05-24 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.506 Å) | | 主引用文献 | Crystal Structure of Nucleosome-H1.0 Linker Histone Assembly (sticky-169an DNA fragment)
To Be Published
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7YWX
 | | Structure of the human CCAN CENP-A alpha-satellite complex | | 分子名称: | Centromere protein C, Centromere protein H, Centromere protein I, ... | | 著者 | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | | 登録日 | 2022-02-14 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (12 Å) | | 主引用文献 | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
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7YYH
 | | Structure of the human CCANdeltaT CENP-A alpha-satellite complex | | 分子名称: | Centromere protein C, Centromere protein H, Centromere protein I, ... | | 著者 | Yatskevich, S, Muir, K.W, Bellini, D, Zhang, Z, Yang, J, Tischer, T, Predin, M, Dendooven, T, McLaughlin, S.H, Barford, D. | | 登録日 | 2022-02-17 | | 公開日 | 2022-05-18 | | 最終更新日 | 2024-07-17 | | 実験手法 | ELECTRON MICROSCOPY (8.9 Å) | | 主引用文献 | Structure of the human inner kinetochore bound to a centromeric CENP-A nucleosome.
Science, 376, 2022
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4Z5T
 | | The nucleosome containing human H3.5 | | 分子名称: | DNA (146-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Urahama, T, Harada, A, Maehara, K, Horikoshi, N, Sato, K, Sato, Y, Shiraishi, K, Sugino, N, Osakabe, A, Tachiwana, H, Kagawa, W, Kimura, H, Ohkawa, Y, Kurumizaka, H. | | 登録日 | 2015-04-03 | | 公開日 | 2016-02-10 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis.
Epigenetics Chromatin, 9, 2016
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8GRQ
 | | Cryo-EM structure of BRCA1/BARD1 bound to H2AK127-UbcH5c-Ub nucleosome | | 分子名称: | BRCA1-associated RING domain protein 1, Breast cancer type 1 susceptibility protein, DNA (147-MER), ... | | 著者 | Ai, H.S, Zebin, T, Zhiheng, D, Jiakun, T, Liying, Z, Jia-Bin, L, Man, P, Liu, L. | | 登録日 | 2022-09-02 | | 公開日 | 2023-04-12 | | 最終更新日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (3.87 Å) | | 主引用文献 | Synthetic E2-Ub-nucleosome conjugates for studying nucleosome ubiquitination.
Chem, 2023
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4IXN
 | | Crystal Structure of Zn(II)-bound E37A,C66A,C67A triple mutant YjiA GTPase | | 分子名称: | SULFATE ION, Uncharacterized GTP-binding protein YjiA, ZINC ION | | 著者 | Jost, M, Drennan, C.L. | | 登録日 | 2013-01-26 | | 公開日 | 2013-02-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Metal binding properties of Escherichia coli YjiA, a member of the metal homeostasis-associated COG0523 family of GTPases.
Biochemistry, 52, 2013
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3BGR
 | | Crystal structure of K103N/Y181C mutant HIV-1 reverse transcriptase (RT) in complex with TMC278 (Rilpivirine), a non-nucleoside RT inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, Reverse transcriptase/ribonuclease H, ... | | 著者 | Das, K, Bauman, J.D, Clark Jr, A.D, Shatkin, A.J, Arnold, E. | | 登録日 | 2007-11-27 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: Strategic flexibility explains potency against resistance mutations.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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2ZD1
 | | Crystal Structure of HIV-1 Reverse Transcriptase (RT) in Complex with TMC278 (Rilpivirine), A Non-nucleoside RT Inhibitor | | 分子名称: | 1,2-ETHANEDIOL, 4-{[4-({4-[(E)-2-cyanoethenyl]-2,6-dimethylphenyl}amino)pyrimidin-2-yl]amino}benzonitrile, Reverse transcriptase/ribonuclease H, ... | | 著者 | Das, K, Bauman, J.D, Clark Jr, A.D, Shatkin, A.J, Arnold, E. | | 登録日 | 2007-11-16 | | 公開日 | 2008-02-12 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | High-resolution structures of HIV-1 reverse transcriptase/TMC278 complexes: Strategic flexibility explains potency against resistance mutations.
Proc.Natl.Acad.Sci.Usa, 105, 2008
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9K9L
 | | Cryo-EM structure of the human CENP-A-H4 octasome. | | 分子名称: | Histone H3-like centromeric protein A, Histone H4, Widom601 DNA FW (145-MER), ... | | 著者 | Nozawa, K, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2024-10-27 | | 公開日 | 2025-04-30 | | 最終更新日 | 2025-06-25 | | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | | 主引用文献 | Cryo-EM Analysis of a Unique Subnucleosome Containing Centromere-Specific Histone Variant CENP-A.
Genes Cells, 30, 2025
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4IXM
 | | Crystal structure of Zn(II)-bound YjiA GTPase from E. coli | | 分子名称: | SULFATE ION, Uncharacterized GTP-binding protein YjiA, ZINC ION | | 著者 | Jost, M, Ryan, K.S, Turo, K.E, Drennan, C.L. | | 登録日 | 2013-01-26 | | 公開日 | 2013-02-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Metal binding properties of Escherichia coli YjiA, a member of the metal homeostasis-associated COG0523 family of GTPases.
Biochemistry, 52, 2013
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7N40
 | | Crystal structure of LIN9-RbAp48-LIN37, a MuvB subcomplex | | 分子名称: | Histone-binding protein RBBP4, Isoform 2 of Protein lin-9 homolog, Protein lin-37 homolog | | 著者 | Asthana, A, Ramanan, P, Tripathi, S.M, Rubin, S.M. | | 登録日 | 2021-06-02 | | 公開日 | 2022-02-09 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes.
Nat Commun, 13, 2022
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4R25
 | | Structure of B. subtilis GlnK | | 分子名称: | Nitrogen regulatory PII-like protein, ZINC ION | | 著者 | Schumacher, M.A. | | 登録日 | 2014-08-08 | | 公開日 | 2015-03-04 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.5193 Å) | | 主引用文献 | Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
Genes Dev., 29, 2015
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