7EPU

Crystal structure of HsALC1

Summary for 7EPU

Entry DOI	10.2210/pdb7epu/pdb
Descriptor	non-immunized human scFv, Chromodomain-helicase-DNA-binding protein 1-like, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total)
Functional Keywords	macrodomain, autoinhibition, dna damage, parp1, motor protein
Biological source	Homo sapiens More
Total number of polymer chains	2
Total formula weight	127613.07
Authors	Wang, L.,Chen, K.J. (deposition date: 2021-04-27, release date: 2021-07-14, Last modification date: 2023-11-29)
Primary citation	Wang, L.,Chen, K.,Chen, Z. Structural basis of ALC1/CHD1L autoinhibition and the mechanism of activation by the nucleosome. Nat Commun, 12:4057-4057, 2021 Cited by PubMed: 34210977 DOI: 10.1038/s41467-021-24320-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation