7EPU
Crystal structure of HsALC1
Summary for 7EPU
Entry DOI | 10.2210/pdb7epu/pdb |
Descriptor | non-immunized human scFv, Chromodomain-helicase-DNA-binding protein 1-like, ADENOSINE-5'-DIPHOSPHATE, ... (4 entities in total) |
Functional Keywords | macrodomain, autoinhibition, dna damage, parp1, motor protein |
Biological source | Homo sapiens More |
Total number of polymer chains | 2 |
Total formula weight | 127613.07 |
Authors | Wang, L.,Chen, K.J. (deposition date: 2021-04-27, release date: 2021-07-14, Last modification date: 2023-11-29) |
Primary citation | Wang, L.,Chen, K.,Chen, Z. Structural basis of ALC1/CHD1L autoinhibition and the mechanism of activation by the nucleosome. Nat Commun, 12:4057-4057, 2021 Cited by PubMed: 34210977DOI: 10.1038/s41467-021-24320-4 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.5 Å) |
Structure validation
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