PDB: 224004 件ウェブページステータス検索Chemie searchBIRD

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4G9K	Structure of the Ndi1 protein from Saccharomyces cerevisiae 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, Rotenone-insensitive NADH-ubiquinone oxidoreductase 著者 Iwata, M, Lee, Y, Yamashita, T, Yagi, T, Iwata, S, Cameron, A.D, Maher, M.J. 登録日 2012-07-24 公開日 2012-09-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 The structure of the yeast NADH dehydrogenase (Ndi1) reveals overlapping binding sites for water- and lipid-soluble substrates. Proc.Natl.Acad.Sci.USA, 109, 2012
4O6Z	Crystal structure of serine hydroxymethyltransferase with covalently bound PLP Schiff-base from Plasmodium falciparum 分子名称: PHOSPHATE ION, PYRIDOXAL-5'-PHOSPHATE, Serine hydroxymethyltransferase 著者 Chitnumsub, P, Jaruwat, A, Leartsakulpanich, U. 登録日 2013-12-24 公開日 2014-06-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 The structure of Plasmodium falciparum serine hydroxymethyltransferase reveals a novel redox switch that regulates its activities. Acta Crystallogr.,Sect.D, 70, 2014
3UE1	Crystal strucuture of Acinetobacter baumanni PBP1A in complex with MC-1 分子名称: (4S,7Z)-7-(2-amino-1,3-thiazol-4-yl)-1-[({4-[(2R)-2,3-dihydroxypropyl]-3-(4,5-dihydroxypyridin-2-yl)-5-oxo-4,5-dihydro- 1H-1,2,4-triazol-1-yl}sulfonyl)amino]-4-formyl-10,10-dimethyl-1,6-dioxo-9-oxa-2,5,8-triazaundec-7-en-11-oate, Penicillin-binding protein 1a 著者 Han, S. 登録日 2011-10-28 公開日 2011-12-14 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 Distinctive attributes of beta-lactam target proteins in Acinetobacter baumannii relevant to development of new antibiotics J.Am.Chem.Soc., 133, 2011
4OHX	C. Elegans Clp1 bound to ADP and Mg2+ (RNA released state) 分子名称: ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, NONAETHYLENE GLYCOL, ... 著者 Dikfidan, A, Loll, B, Zeymer, C, Clausen, T, Meinhart, A. 登録日 2014-01-18 公開日 2014-05-14 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 RNA specificity and regulation of catalysis in the eukaryotic polynucleotide kinase clp1. Mol.Cell, 54, 2014
3URE	Repack mutant (T181I, W199L, Q210I) of alpha-Lytic Protease 分子名称: Alpha-lytic protease, SULFATE ION 著者 Kelch, B.A, Agard, D.A. 登録日 2011-11-22 公開日 2012-05-23 最終更新日 2012-07-18 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Functional modulation of a protein folding landscape via side-chain distortion. Proc.Natl.Acad.Sci.USA, 109, 2012
3UEZ	Crystal structure of the human Colony-Stimulating Factor 1 (hCSF-1) cytokine in complex with the viral receptor BARF1 分子名称: Macrophage colony-stimulating factor 1, Secreted protein BARF1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Elegheert, J, Bracke, N, Savvides, S.N. 登録日 2011-10-31 公開日 2012-08-22 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.414 Å) 主引用文献 Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1 Nat.Struct.Mol.Biol., 19, 2012
2R3I	Crystal Structure of Cyclin-Dependent Kinase 2 with inhibitor 分子名称: 5-(2-fluorophenyl)-N-(pyridin-4-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine, Cell division protein kinase 2 著者 Fischmann, T.O, Hruza, A.W, Madison, V.M, Duca, J.S. 登録日 2007-08-29 公開日 2008-01-22 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.28 Å) 主引用文献 Structure-guided discovery of cyclin-dependent kinase inhibitors. Biopolymers, 89, 2008
3URY	Crystal Structure of Superantigen-like Protein, Exotoxin from Staphylococcus aureus subsp. aureus NCTC 8325 分子名称: CHLORIDE ION, Exotoxin 著者 Filippova, E.V, Minasov, G, Shuvalova, L, Halavaty, A, Winsor, J, Dubrovska, I, Bagnoli, F, Falugi, F, Bottomley, M, Grandi, G, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-11-22 公開日 2011-12-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal Structure of Superantigen-like Protein, Exotoxin from Staphylococcus aureus subsp. aureus NCTC 8325 To be Published
4OIA	Crystal Structure of ICAM-5 D1-D4 ectodomain fragment, Space Group P4322 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Recacha, R, Jimenez, D, Tian, L, Barredo, R, Ghamberg, C, Casasnovas, J.M. 登録日 2014-01-19 公開日 2014-07-16 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Crystal structures of an ICAM-5 ectodomain fragment show electrostatic-based homophilic adhesions. Acta Crystallogr.,Sect.D, 70, 2014
3UFP	Structure of rat nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-((5-(3-fluorophenyl)pentyl)oxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, 6-{[(3R,4R)-4-{[5-(3-fluorophenyl)pentyl]oxy}pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2011-11-01 公開日 2012-07-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Selective monocationic inhibitors of neuronal nitric oxide synthase. Binding mode insights from molecular dynamics simulations. J.Am.Chem.Soc., 134, 2012
4GE2	Crystal structure of human protein tyrosine phosphatase PTPN9 (MEG2) complex with compound 3 分子名称: N-acetyl-4-[difluoro(phosphono)methyl]-L-phenylalanyl-N~5~-(3-iodobenzoyl)-L-ornithinamide, Tyrosine-protein phosphatase non-receptor type 9 著者 Zhang, Z.-Y, Liu, S, Zhang, S. 登録日 2012-08-01 公開日 2012-10-31 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 A Highly Selective and Potent PTP-MEG2 Inhibitor with Therapeutic Potential for Type 2 Diabetes. J.Am.Chem.Soc., 134, 2012
4O8F	Crystal Structure of the complex between PPARgamma mutant R357A and rosiglitazone 分子名称: 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), Peroxisome proliferator-activated receptor gamma 著者 Pochetti, G, Montanari, R, Capelli, D, Chiaraluce, R, Consalvi, V, Lori, C, Loiodice, F, Laghezza, A, Pasquo, A, Cervoni, L, Aschi, M. 登録日 2013-12-27 公開日 2014-07-23 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural basis of the transactivation deficiency of the human PPAR gamma F360L mutant associated with familial partial lipodystrophy. Acta Crystallogr.,Sect.D, 70, 2014
4O8R	Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with 5,6-dihydrouridine 5'-monophosphate 分子名称: 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE, CHLORIDE ION, Orotidine 5'-phosphate decarboxylase 著者 Fedorov, A.A, Fedorov, E.V, Chan, K.K, Gerlt, J.A, Almo, S.C. 登録日 2013-12-29 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.293 Å) 主引用文献 Crystal structure of orotidine 5'-monophosphate decarboxylase from methanobacterium thermoautotrophicum complexed with 5,6-dihydrouridine 5'-monophosphate To be Published
3UGK	Crystal Structure of C205S mutant and Saccharopine Dehydrogenase from Saccharomyces cerevisiae. 分子名称: Saccharopine dehydrogenase [NAD+, L-lysine-forming] 著者 Cook, P.F, Kumar, V.P, Thomas, L.M, West, A.H, Bobyk, K.D. 登録日 2011-11-02 公開日 2012-02-01 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Evidence in Support of Lysine 77 and Histidine 96 as Acid-Base Catalytic Residues in Saccharopine Dehydrogenase from Saccharomyces cerevisiae. Biochemistry, 51, 2012
4OK1	Crystal structure of W741L-AR-LBD bound with co-regulator peptide 分子名称: Androgen receptor, R-BICALUTAMIDE, co-regulator peptide 著者 Liu, J.S, Hsu, C.L, Wu, W.G. 登録日 2014-01-21 公開日 2014-08-20 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis. Mol Oncol, 8, 2014
4OAK	Crystal structure of vancomycin resistance D,D-dipeptidase/D,D-pentapeptidase VanXYc D59S mutant in complex with D-Alanine-D-Alanine and copper (II) 分子名称: 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL, CHLORIDE ION, COPPER (II) ION, ... 著者 Stogios, P.J, Evdokimova, E, Meziane-Cherif, D, Di Leo, R, Yim, V, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2014-01-04 公開日 2014-01-15 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural basis for the evolution of vancomycin resistance D,D-peptidases. Proc.Natl.Acad.Sci.USA, 111, 2014
3UGS	Crystal structure of a probable undecaprenyl diphosphate synthase (uppS) from Campylobacter jejuni 分子名称: (2Z,6Z)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl dihydrogen phosphate, Undecaprenyl pyrophosphate synthase 著者 Nocek, B, Gu, M, Grimshaw, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2011-11-02 公開日 2011-11-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.457 Å) 主引用文献 Crystal structure of a probable undecaprenyl diphosphate synthase (uppS) from Campylobacter jejuni TO BE PUBLISHED
2QVJ	Crystal structure of a vesicular stomatitis virus nucleocapsid protein Ser290Trp mutant 分子名称: Nucleocapsid protein 著者 Luo, M, Green, T.J, Zhang, X, Tsao, J, Qiu, S. 登録日 2007-08-08 公開日 2008-01-08 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Role of intermolecular interactions of vesicular stomatitis virus nucleoprotein in RNA encapsidation. J.Virol., 82, 2008
3USK	Crystal structure of LeuT bound to L-leucine in space group P21 from lipid bicelles 分子名称: LEUCINE, SODIUM ION, Transporter 著者 Wang, H, Elferich, J, Gouaux, E. 登録日 2011-11-23 公開日 2012-01-11 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (4.5 Å) 主引用文献 Structures of LeuT in bicelles define conformation and substrate binding in a membrane-like context. Nat.Struct.Mol.Biol., 19, 2012
4OKY	Crystal structure of PvuRts1I, a 5-hydroxymethylcytosine DNA restriction endonuclease 分子名称: Restriction endonuclease PvuRts1 I 著者 Wang, C.L, Shao, C, Zang, J.Y. 登録日 2014-01-23 公開日 2014-09-10 最終更新日 2014-12-17 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for the substrate selectivity of PvuRts1I, a 5-hydroxymethylcytosine DNA restriction endonuclease Acta Crystallogr.,Sect.D, 70, 2014
3UGY	HBI (F80Y) CO bound 分子名称: CARBON MONOXIDE, Globin-1, PROTOPORPHYRIN IX CONTAINING FE 著者 Ren, Z, Srajer, V, Knapp, J.E, Royer Jr, W.E. 登録日 2011-11-03 公開日 2011-12-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures. Proc.Natl.Acad.Sci.USA, 109, 2012
4OAS	co-crystal structure of MDM2 (17-111) in complex with compound 25 分子名称: E3 ubiquitin-protein ligase Mdm2, SULFATE ION, [(3R,5R,6S)-1-[(2S)-1-(tert-butylsulfonyl)butan-2-yl]-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-2-oxopiperidin-3-yl]acetic acid 著者 Huang, X. 登録日 2014-01-06 公開日 2014-02-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Discovery of AMG 232, a Potent, Selective, and Orally Bioavailable MDM2-p53 Inhibitor in Clinical Development. J.Med.Chem., 57, 2014
3UH4	TANKYRASE-1 complexed with NVP-XAV939 分子名称: 2-[4-(trifluoromethyl)phenyl]-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-4-ol, GLYCEROL, SULFATE ION, ... 著者 Stams, T, Kirby, C. 登録日 2011-11-03 公開日 2012-02-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of human tankyrase 1 in complex with small-molecule inhibitors PJ34 and XAV939. Acta Crystallogr.,Sect.F, 68, 2012
3UHL	Crystal Structure of Multidrug Resistant HIV-1 Protease Clinical Isolate PR20 in Complex with p2-NC substrate analog 分子名称: N-{(2S)-2-[(N-acetyl-L-threonyl-L-isoleucyl)amino]hexyl}-L-norleucyl-L-glutaminyl-N~5~-[amino(iminio)methyl]-L-ornithinamide, Protease, SULFATE ION 著者 Agniswamy, J, Chen-Hsiang, S, Weber, I. 登録日 2011-11-03 公開日 2012-03-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 HIV-1 protease with 20 mutations exhibits extreme resistance to clinical inhibitors through coordinated structural rearrangements. Biochemistry, 51, 2012
4OLK	The CHAP domain of LysGH15 分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Endolysin 著者 Gu, J, Ouyang, S, Liu, Z.J, Han, W. 登録日 2014-01-24 公開日 2014-05-28 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.694 Å) 主引用文献 Structural and biochemical characterization reveals LysGH15 as an unprecedented "EF-hand-like" calcium-binding phage lysin. Plos Pathog., 10, 2014

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