4OAK

Crystal structure of vancomycin resistance D,D-dipeptidase/D,D-pentapeptidase VanXYc D59S mutant in complex with D-Alanine-D-Alanine and copper (II)

Summary for 4OAK

Entry DOI	10.2210/pdb4oak/pdb
Related	4F78 4MUQ 4MUR 4MUS 4MUT
Descriptor	D,D-dipeptidase/D,D-carboxypeptidase, COPPER (II) ION, D-ALANINE, ... (8 entities in total)
Functional Keywords	center for structural genomics of infectious diseases, csgid, national institute of allergy and infectious diseases, niaid, alpha+beta protein, metallopeptidase, hedgehog/dd-peptidase fold, merops m15b subfamily, zn2+-dependent, vancomycin resistance, antibiotic resistance, hydrolase
Biological source	Enterococcus gallinarum
Total number of polymer chains	2
Total formula weight	53079.59
Authors	Stogios, P.J.,Evdokimova, E.,Meziane-Cherif, D.,Di Leo, R.,Yim, V.,Courvalin, P.,Savchenko, A.,Anderson, W.F.,Center for Structural Genomics of Infectious Diseases (CSGID) (deposition date: 2014-01-04, release date: 2014-01-15, Last modification date: 2023-09-20)
Primary citation	Meziane-Cherif, D.,Stogios, P.J.,Evdokimova, E.,Savchenko, A.,Courvalin, P. Structural basis for the evolution of vancomycin resistance D,D-peptidases. Proc.Natl.Acad.Sci.USA, 111:5872-5877, 2014 Cited by PubMed: 24711382 DOI: 10.1073/pnas.1402259111 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation