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8CRX
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Cutibacterium acnes 70S ribosome with mRNA, P-site tRNA and Sarecycline bound
分子名称: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Lomakin, I.B, Devarkar, S.C, Bunick, C.G.
登録日2022-05-12
公開日2023-03-22
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (2.78 Å)
主引用文献Sarecycline inhibits protein translation in Cutibacterium acnes 70S ribosome using a two-site mechanism.
Nucleic Acids Res., 51, 2023
4U4U
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Crystal structure of Lycorine bound to the yeast 80S ribosome
分子名称: (1S,2S,12bS,12cS)-2,4,5,7,12b,12c-hexahydro-1H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-1,2-diol, 18S ribosomal RNA, 25S ribosomal RNA, ...
著者Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
登録日2014-07-24
公開日2014-10-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
4U3N
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Crystal structure of CCA trinucleotide bound to the yeast 80S ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
登録日2014-07-22
公開日2014-10-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
8EV6
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Crystal structure of the Thermus thermophilus 70S ribosome in complex with amikacin, mRNA, and A-, P-, and E-site tRNAs
分子名称: (2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S ,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide, 16S Ribosomal RNA, 23S Ribosomal RNA, ...
著者Seely, S.M, Gagnon, M.G.
登録日2022-10-19
公開日2023-08-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.946 Å)
主引用文献Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome.
Nat Commun, 14, 2023
8EV7
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Crystal structure of the Thermus thermophilus 70S ribosome in complex with kanamycin, mRNA, and A-, P-, and E-site tRNAs
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Seely, S.M, Gagnon, M.G.
登録日2022-10-19
公開日2023-08-09
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.89 Å)
主引用文献Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome.
Nat Commun, 14, 2023
8EVP
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Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), Structure I
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-20
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.38 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EUB
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Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure I
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S0-A, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-18
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.52 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EVQ
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Hypopseudouridylated Ribosome bound with TSV IRES, eEF2, GDP, and sordarin, Structure I
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-20
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EVR
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Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2, GDP, and sordarin, Structure II
分子名称: (1S,3S,3aR,4S,4aR,7R,7aR,8aS)-8a-{[(6-deoxy-4-O-methyl-alpha-D-altropyranosyl)oxy]methyl}-4-formyl-7-methyl-3-(propan-2-yl)decahydro-1,4-methano-s-indacene-3a(1H)-carboxylate, 18S rRNA, 25S rRNA, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-20
公開日2023-09-06
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.87 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EVS
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Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure II
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-20
公開日2023-09-06
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.62 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EWB
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BU of 8ewb by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure III
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-22
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.87 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
8EWC
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BU of 8ewc by Molmil
Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), Structure II
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-22
公開日2023-09-06
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
4UG0
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STRUCTURE OF THE HUMAN 80S RIBOSOME
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S RIBOSOMAL PROTEIN, ...
著者Khatter, H, Myasnikov, A.G, Natchiar, S.K, Klaholz, B.P.
登録日2015-03-20
公開日2015-06-10
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of the human 80S ribosome
NATURE, 520, 2015
8EVT
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Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES) refined against a composite map
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Zhao, Y, Rai, J, Li, H.
登録日2022-10-20
公開日2023-09-06
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Regulation of translation by ribosomal RNA pseudouridylation.
Sci Adv, 9, 2023
4V7F
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BU of 4v7f by Molmil
Arx1 pre-60S particle.
分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Leidig, C, Thoms, M, Holdermann, I, Bradatsch, B, Berninghausen, O, Bange, G, Sinning, I, Hurt, E, Beckmann, R.
登録日2013-12-10
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (8.7 Å)
主引用文献60S ribosome biogenesis requires rotation of the 5S ribonucleoprotein particle.
Nat Commun, 5, 2014
4V4B
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BU of 4v4b by Molmil
Structure of the ribosomal 80S-eEF2-sordarin complex from yeast obtained by docking atomic models for RNA and protein components into a 11.7 A cryo-EM map.
分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11, ...
著者Spahn, C.M, Gomez-Lorenzo, M.G, Grassucci, R.A, Jorgensen, R, Andersen, G.R, Beckmann, R, Penczek, P.A, Ballesta, J.P.G, Frank, J.
登録日2004-01-06
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (11.7 Å)
主引用文献Domain movements of elongation factor eEF2 and the eukaryotic 80S ribosome facilitate tRNA translocation.
Embo J., 23, 2004
4V6C
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Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Zhang, W, Dunkle, J.A, Cate, J.H.D.
登録日2009-06-27
公開日2014-07-09
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Structures of the ribosome in intermediate States of ratcheting.
Science, 325, 2009
4V6W
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Structure of the D. melanogaster 80S ribosome
分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 2S ribosomal RNA, ...
著者Anger, A.M, Armache, J.-P, Berninghausen, O, Habeck, M, Subklewe, M, Wilson, D.N, Beckmann, R.
登録日2013-02-27
公開日2014-07-09
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Structures of the human and Drosophila 80S ribosome.
Nature, 497, 2013
6O3M
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BU of 6o3m by Molmil
Unmodified tRNA(Pro) bound to Thermus thermophilus 70S (cognate)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M.
登録日2019-02-26
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.97 Å)
主引用文献Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
6NSH
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BU of 6nsh by Molmil
Modified ASL proline bound to Thermus thermophilus 70S (near-cognate)
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M.
登録日2019-01-24
公開日2020-10-14
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.397 Å)
主引用文献Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
4V4I
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BU of 4v4i by Molmil
Crystal Structure of a 70S Ribosome-tRNA Complex Reveals Functional Interactions and Rearrangements.
分子名称: 16S SMALL SUBUNIT RIBOSOMAL RNA, 23S LARGE SUBUNIT RIBOSOMAL RNA, 30S ribosomal protein S10, ...
著者Korostelev, A, Trakhanov, S, Laurberg, M, Noller, H.F.
登録日2007-02-15
公開日2014-07-09
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.71 Å)
主引用文献Crystal Structure of a 70S Ribosome-tRNA Complex Reveals Functional Interactions and Rearrangements
Cell(Cambridge,Mass.), 126, 2006
4V4W
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Structure of a SecM-stalled E. coli ribosome complex obtained by fitting atomic models for RNA and protein components into cryo-EM map EMD-1143
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal subunit protein S10, ...
著者Mitra, K, Frank, J.
登録日2006-05-09
公開日2014-07-09
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (15 Å)
主引用文献Elongation arrest by SecM via a cascade of ribosomal RNA rearrangements
Mol.Cell, 22, 2006
4V7S
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Crystal structure of the E. coli ribosome bound to telithromycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D.
登録日2010-08-05
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.2547 Å)
主引用文献Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action.
Proc.Natl.Acad.Sci.USA, 107, 2010
8P8U
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Yeast 60S ribosomal subunit
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Rabl, J, Banerjee, A, Boehringer, D, Zavolan, M.
登録日2023-06-02
公開日2024-06-12
実験手法ELECTRON MICROSCOPY (2.23 Å)
主引用文献Yeast 60S ribosomal subunit
To Be Published
4V8Y
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Cryo-EM reconstruction of the 80S-eIF5B-Met-itRNAMet Eukaryotic Translation Initiation Complex
分子名称: 18S RIBOSOMAL RNA, 25S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN S0-A, ...
著者Fernandez, I.S, Bai, X.C, Hussain, T, Kelley, A.C, Lorsch, J.R, Ramakrishnan, V, Scheres, S.H.W.
登録日2013-07-20
公開日2014-07-09
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Molecular architecture of a eukaryotic translational initiation complex.
Science, 342, 2013

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