7CA3
 
 | | Cryo-EM structure of human GABA(B) receptor bound to the positive allosteric modulator rac-BHFF | | 分子名称: | (3S)-5,7-ditert-butyl-3-oxidanyl-3-(trifluoromethyl)-1-benzofuran-2-one, CHOLESTEROL, Gamma-aminobutyric acid type B receptor subunit 1, ... | | 著者 | Kim, Y, Jeong, E, Jeong, J, Kim, Y, Cho, Y. | | 登録日 | 2020-06-08 | | 公開日 | 2020-11-11 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | Structural Basis for Activation of the Heterodimeric GABA B Receptor.
J.Mol.Biol., 432, 2020
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6U8Q
 | | CryoEM structure of HIV-1 cleaved synaptic complex (CSC) intasome | | 分子名称: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... | | 著者 | Li, M, Chen, X, Craigie, R. | | 登録日 | 2019-09-05 | | 公開日 | 2020-02-05 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.67 Å) | | 主引用文献 | A Peptide Derived from Lens Epithelium-Derived Growth Factor Stimulates HIV-1 DNA Integration and Facilitates Intasome Structural Studies.
J.Mol.Biol., 432, 2020
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1JDH
 | | CRYSTAL STRUCTURE OF BETA-CATENIN AND HTCF-4 | | 分子名称: | BETA-CATENIN, hTcf-4 | | 著者 | Graham, T.A, Ferkey, D.M, Mao, F, Kimelman, D, Xu, W. | | 登録日 | 2001-06-13 | | 公開日 | 2001-12-05 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Tcf4 can specifically recognize beta-catenin using alternative conformations.
Nat.Struct.Biol., 8, 2001
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1JB6
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6E3B
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1JBL
 | | Solution structure of SFTI-1, A cyclic trypsin inhibitor from sunflower seeds | | 分子名称: | CYCLIC TRYPSIN INHIBITOR | | 著者 | Korsinczky, M.L.J, Schirra, H.J, Rosengren, K.J, West, J, Condie, B.A, Otvos, L, Anderson, M.A, Craik, D.J. | | 登録日 | 2001-06-05 | | 公開日 | 2001-08-22 | | 最終更新日 | 2015-04-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structures by 1H NMR of the novel cyclic trypsin inhibitor SFTI-1 from sunflower seeds and an acyclic permutant.
J.Mol.Biol., 311, 2001
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6UAG
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2HPD
 | | CRYSTAL STRUCTURE OF HEMOPROTEIN DOMAIN OF P450BM-3, A PROTOTYPE FOR MICROSOMAL P450'S | | 分子名称: | CYTOCHROME P450 BM-3, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Ravichandran, K.G, Boddupalli, S.S, Hasemann, C.A, Peterson, J.A, Deisenhofer, J. | | 登録日 | 1993-09-16 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's.
Science, 261, 1993
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1JDX
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7CW3
 | | Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG (subregion around icosahedral 2-fold vertex) | | 分子名称: | Capsid protein, E1 glycoprotein, E2 glycoprotein, ... | | 著者 | Zhou, Q.F, Fox, J.M, Earnest, J.T, Ng, T.S, Kim, A.S, Fibriansah, G, Kostyuchenko, V.A, Shu, B, Diamond, M.S, Lok, S.M. | | 登録日 | 2020-08-27 | | 公開日 | 2020-11-04 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (9.4 Å) | | 主引用文献 | Structural basis of Chikungunya virus inhibition by monoclonal antibodies.
Proc.Natl.Acad.Sci.USA, 117, 2020
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8DC2
 | | Cryo-EM structure of CasLambda (Cas12l) bound to crRNA and DNA | | 分子名称: | CasLambda, DNA NTS, DNA TS, ... | | 著者 | Al-Shayeb, B, Skopintsev, P, Soczek, K, Doudna, J. | | 登録日 | 2022-06-15 | | 公開日 | 2022-12-14 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (2.99 Å) | | 主引用文献 | Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors.
Cell, 185, 2022
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1JDQ
 | | Solution Structure of TM006 Protein from Thermotoga maritima | | 分子名称: | HYPOTHETICAL PROTEIN TM0983 | | 著者 | Denisov, A.Y, Finak, G, Yee, A, Kozlov, G, Gehring, K, Arrowsmith, C.H. | | 登録日 | 2001-06-14 | | 公開日 | 2002-02-27 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | An NMR approach to structural proteomics.
Proc.Natl.Acad.Sci.USA, 99, 2002
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6L6S
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6L7C
 | | CsgFG complex with substrate CsgAN6 peptide in Curli biogenesis system | | 分子名称: | CsgF, Curli production assembly/transport protein CsgG, Major curlin subunit CsgA | | 著者 | Yan, Z.F, Yin, M, Chen, J.N, Li, X.M. | | 登録日 | 2019-11-01 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.34 Å) | | 主引用文献 | Assembly and substrate recognition of curli biogenesis system.
Nat Commun, 11, 2020
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6E8C
 | | Crystal structure of the double homeodomain of DUX4 in complex with DNA | | 分子名称: | DNA (5'-D(*GP*CP*GP*TP*AP*AP*TP*CP*TP*AP*AP*TP*CP*AP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*GP*AP*TP*TP*AP*GP*AP*TP*TP*AP*CP*GP*C)-3'), Double homeobox protein 4 | | 著者 | Lee, J.K, Bosnakovski, D, Toso, E.A, Dinh, T, Banerjee, S, Bohl, T.E, Shi, K, Kurahashi, K, Kyba, M, Aihara, H. | | 登録日 | 2018-07-27 | | 公開日 | 2018-12-26 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Crystal Structure of the Double Homeodomain of DUX4 in Complex with DNA.
Cell Rep, 25, 2018
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7CKQ
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6L8H
 | | Crystal structure of CYP97C1 | | 分子名称: | Carotene epsilon-monooxygenase, chloroplastic, GLYCEROL, ... | | 著者 | Niu, G, Guo, Q, Liu, L. | | 登録日 | 2019-11-06 | | 公開日 | 2020-06-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural basis for plant lutein biosynthesis from alpha-carotene.
Proc.Natl.Acad.Sci.USA, 117, 2020
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6U0K
 | | TTBK2 kinase domain in complex with Compound 1 | | 分子名称: | 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Marcotte, D.J, Chodaparambil, J.V. | | 登録日 | 2019-08-14 | | 公開日 | 2020-03-11 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.744 Å) | | 主引用文献 | The crystal structure of the catalytic domain of tau tubulin kinase 2 in complex with a small-molecule inhibitor
Acta Crystallogr.,Sect.F, 76, 2020
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6ED1
 | | Bacteroides dorei Beta-glucuronidase | | 分子名称: | Glycosyl hydrolase family 2, sugar binding domain protein, SODIUM ION | | 著者 | Biernat, K.A, Redinbo, M.R. | | 登録日 | 2018-08-08 | | 公開日 | 2019-02-13 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure, function, and inhibition of drug reactivating human gut microbial beta-glucuronidases.
Sci Rep, 9, 2019
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8IOG
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7LSZ
 | | Hsp90a N-terminal inhibitor | | 分子名称: | Heat shock protein HSP 90-alpha, {3-[(2,3-dihydro-1,4-benzodioxin-6-yl)sulfanyl]-4-hydroxyphenyl}(1,3-dihydro-2H-isoindol-2-yl)methanone | | 著者 | Balch, M, Peng, S, Deng, J, Matts, R. | | 登録日 | 2021-02-18 | | 公開日 | 2021-03-03 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Selective Inhibition of the Hsp90 alpha Isoform.
Angew.Chem.Int.Ed.Engl., 60, 2021
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2ID4
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2IDM
 | | 2.00 A Structure of T87I/Y106W Phosphono-CheY | | 分子名称: | ACETATE ION, Chemotaxis protein cheY | | 著者 | Halkides, C.J, Haas, R.M, McAdams, K.A, Casper, E.S, Santarsiero, B.D, Mesecar, A.D. | | 登録日 | 2006-09-15 | | 公開日 | 2007-09-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structures of T87I phosphono-CheY and T87I/Y106W phosphono-CheY help to explain their binding affinities to the FliM and CheZ peptides.
Arch.Biochem.Biophys., 479, 2008
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2IDS
 | | Structure of M98A mutant of amicyanin, Cu(I) | | 分子名称: | Amicyanin, COPPER (I) ION | | 著者 | Carrell, C.J, Ma, J.K, Antholine, W, Hosler, J.P, Mathews, F.S, Davidson, V.L. | | 登録日 | 2006-09-15 | | 公開日 | 2007-03-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Generation of Novel Copper Sites by Mutation of the Axial Ligand of Amicyanin. Atomic Resolution Structures and Spectroscopic Properties
Biochemistry, 46, 2007
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6KQF
 | | Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 5 nt | | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | | 著者 | Zhang, Y, Li, L, Ebright, R.H. | | 登録日 | 2019-08-17 | | 公開日 | 2020-03-11 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription.
Proc.Natl.Acad.Sci.USA, 117, 2020
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