6U0K

TTBK2 kinase domain in complex with Compound 1

Summary for 6U0K

• Entry DOI: 10.2210/pdb6u0k/pdb
• Descriptor: Tau-tubulin kinase 2, PHOSPHATE ION, 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE, ... (5 entities in total)
• Functional Keywords: ttbk2, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 70446.05

Authors

Marcotte, D.J.,Chodaparambil, J.V. (deposition date: 2019-08-14, release date: 2020-03-11, Last modification date: 2023-10-11)

• Primary citation: Marcotte, D.J.,Spilker, K.A.,Wen, D.,Hesson, T.,Patterson, T.A.,Kumar, R.,Chodaparambil, J.V.; The crystal structure of the catalytic domain of tau tubulin kinase 2 in complex with a small-molecule inhibitor; Acta Crystallogr.,Sect.F, 76:103-108, 2020; DOI: 10.1107/S2053230X2000031X

Experimental method

X-RAY DIFFRACTION (1.744 Å)