8E00
| Symmetry expansion of yeast cytoplasmic dynein-1 bound to Lis1 in the chi conformation. | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Dynein heavy chain, ... | 著者 | Reimer, J.M, Lahiri, I, Leschziner, A.E. | 登録日 | 2022-08-08 | 公開日 | 2023-08-30 | 最終更新日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Lis1 relieves cytoplasmic dynein-1 autoinhibition by acting as a molecular wedge. Nat.Struct.Mol.Biol., 30, 2023
|
|
8R3S
| Transketolase from Staphylococcus aureus in complex with thiamin pyrophosphate | 分子名称: | MAGNESIUM ION, THIAMINE DIPHOSPHATE, Transketolase | 著者 | Ballut, L, Georges, N, Aghajari, N, Hecquet, L, Charmantray, F, Doumeche, B. | 登録日 | 2023-11-10 | 公開日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Are Transketolases relevant Targets fighting Human Pathogens? A comparative Biochemical, Bioinformatic and Structural Study To Be Published
|
|
8RVE
| Vimentin intermediate filament | 分子名称: | Vimentin | 著者 | Eibauer, M, Medalia, O. | 登録日 | 2024-02-01 | 公開日 | 2024-04-10 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (7.2 Å) | 主引用文献 | Vimentin filaments integrate low-complexity domains in a complex helical structure. Nat.Struct.Mol.Biol., 31, 2024
|
|
8QJ0
| Room-temperature Serial Synchrotron Crystallography structure of Spinacia oleracea RuBisCO | 分子名称: | MAGNESIUM ION, Ribulose bisphosphate carboxylase large chain, Ribulose bisphosphate carboxylase small subunit, ... | 著者 | Bjelcic, M, Neutze, R, Aurelius, O, Nan, J, Ursby, T. | 登録日 | 2023-09-12 | 公開日 | 2024-05-29 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Room-temperature serial synchrotron crystallography structure of Spinacia oleracea RuBisCO. Acta Crystallogr.,Sect.F, 80, 2024
|
|
8QE8
| Structure of the non-canonical CTLH E3 substrate receptor WDR26 bound to NMNAT1 substrate | 分子名称: | BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1, WD repeat-containing protein 26, ... | 著者 | Chrustowicz, J, Sherpa, D, Schulman, B.A. | 登録日 | 2023-08-30 | 公開日 | 2024-05-15 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Non-canonical substrate recognition by the human WDR26-CTLH E3 ligase regulates prodrug metabolism. Mol.Cell, 84, 2024
|
|
8EBK
| |
8RCV
| Crystal structure of HLA B*13:01 in complex with SVLNDIFSRL, an 10-mer epitope from SARS-CoV-2 Spike (S975-984) | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen B alpha chain, ... | 著者 | Ahn, Y.M, Maddumage, J.C, Szeto, C, Gras, S. | 登録日 | 2023-12-07 | 公開日 | 2024-05-15 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The impact of SARS-CoV-2 spike mutation on peptide presentation is HLA allomorph-specific. Curr Res Struct Biol, 7, 2024
|
|
8QZ2
| Crystal structure of human two pore domain potassium ion channel TREK-2 (K2P10.1) in complex with an inhibitory nanobody (Nb61) | 分子名称: | Nanobody 61, POTASSIUM ION, Potassium channel subfamily K member 10 | 著者 | Baronina, A, Pike, A.C.W, Rodstrom, K.E.J, Ang, J, Bushell, S.R, Chalk, R, Mukhopadhyay, S.M.M, Pardon, E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N.A, Tucker, S.J, Steyaert, J, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2023-10-26 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nat Commun, 15, 2024
|
|
8QZ1
| Crystal structure of human two pore domain potassium ion channel TREK-2 (K2P10.1) in complex with a nanobody (Nb58) | 分子名称: | Isoform B of Potassium channel subfamily K member 10, Nanobody 58, POTASSIUM ION | 著者 | Rodstrom, K.E.J, Pike, A.C.W, Baronina, A, Ang, J, Bushell, S.R, Chalk, R, Mukhopadhyay, S.M.M, Pardon, E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N.A, Tucker, S.J, Steyaert, J, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2023-10-26 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.588 Å) | 主引用文献 | Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nat Commun, 15, 2024
|
|
8QZ3
| Crystal structure of human two pore domain potassium ion channel TREK-2 (K2P10.1) in complex with an activatory nanobody (Nb67) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Nanobody 67, POTASSIUM ION, ... | 著者 | Baronina, A, Pike, A.C.W, Rodstrom, K.E.J, Ang, J, Bushell, S.R, Chalk, R, Mukhopadhyay, S.M.M, Pardon, E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N.A, Tucker, S.J, Steyaert, J, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2023-10-26 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nat Commun, 15, 2024
|
|
8R0E
| p97 (VCP) mutant - F266A | 分子名称: | Transitional endoplasmic reticulum ATPase | 著者 | Arie, M, Matzov, D, Karmona, R, Szenkier, N, Stanhill, A, Navon, A. | 登録日 | 2023-10-31 | 公開日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | 主引用文献 | p97 (VCP) mutant - F266A To Be Published
|
|
8DVV
| Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions | 分子名称: | CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ... | 著者 | Iyer, K.A, Hu, Y, Murayama, T, Samso, M. | 登録日 | 2022-07-29 | 公開日 | 2024-01-31 | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | 主引用文献 | Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6 and nanodisc under open-state conditions To Be Published
|
|
8DTY
| |
8DTZ
| |
8QZ4
| Crystal structure of human two pore domain potassium ion channel TREK-2 (K2P10.1) in complex with an activatory nanobody (Nb76) | 分子名称: | BARIUM ION, CHOLESTEROL HEMISUCCINATE, Nanobody 76, ... | 著者 | Rodstrom, K.E.J, Pike, A.C.W, Baronina, A, Ang, J, Bushell, S.R, Chalk, R, Mukhopadhyay, S.M.M, Pardon, E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N.A, Tucker, S.J, Steyaert, J, Carpenter, E.P, Structural Genomics Consortium (SGC) | 登録日 | 2023-10-26 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Extracellular modulation of TREK-2 activity with nanobodies provides insight into the mechanisms of K2P channel regulation. Nat Commun, 15, 2024
|
|
8QRH
| Inactivated tick-borne encephalitis virus (TBEV) vaccine strain Sofjin-Chumakov | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Genome polyprotein, Small envelope protein M | 著者 | Moiseenko, A.V, Zhang, Y, Vorovitch, M, Ivanova, A, Liu, Z, Osolodkin, D.I, Egorov, A, Ishmukhametov, A, Sokolova, O.S. | 登録日 | 2023-10-07 | 公開日 | 2024-06-05 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | The structure of inactivated mature tick-borne encephalitis virus at 3.0 angstrom resolution. Emerg Microbes Infect, 13, 2024
|
|
7T30
| |
7T2R
| |
8R7Y
| Deoxyribonucleoside regulator DeoR in complex with the DNA operator | 分子名称: | Deoxyribonucleoside regulator, OL18 DNA operator, strand 1, ... | 著者 | Pachl, P, Soltysova, M, Rezacova, P. | 登録日 | 2023-11-27 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-17 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structural characterization of two prototypical repressors of SorC family reveals tetrameric assemblies on DNA and mechanism of function. Nucleic Acids Res., 52, 2024
|
|
8EGM
| |
7TAC
| Cryo-EM structure of the (TGA3)2-(NPR1)2-(TGA3)2 complex | 分子名称: | PALMITIC ACID, Regulatory protein NPR1, Transcription factor TGA3, ... | 著者 | Wu, Q, Zhou, Y, Bartesaghi, A, Dong, X, Zhou, P. | 登録日 | 2021-12-20 | 公開日 | 2022-03-16 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis of NPR1 in activating plant immunity. Nature, 605, 2022
|
|
8SOE
| |
8QQI
| E.coli DNA gyrase in complex with 217 bp substrate DNA and LEI-800 | 分子名称: | DNA gyrase subunit A, DNA gyrase subunit B, MAGNESIUM ION, ... | 著者 | Ghilarov, D, Martin, N.I, van der Stelt, M. | 登録日 | 2023-10-04 | 公開日 | 2024-06-19 | 最終更新日 | 2024-09-18 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria. Nat.Chem., 16, 2024
|
|
8QFW
| Murine pyridoxal phosphatase in complex with 7,8-dihydroxyflavone | 分子名称: | 7,8-bis(oxidanyl)-2-phenyl-chromen-4-one, CITRIC ACID, Chronophin, ... | 著者 | Schindelin, H, Gohla, A. | 登録日 | 2023-09-05 | 公開日 | 2024-06-12 | 最終更新日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | 7,8-Dihydroxyflavone is a direct inhibitor of human and murine pyridoxal phosphatase. Elife, 13, 2024
|
|
7TBH
| cryo-EM structure of MBP-KIX-apoferritin complex with peptide 7 | 分子名称: | Isoform 2 of CREB-binding protein,Ferritin heavy chain, N-terminally processed, LEU-SER-ARG-ARG-PRO-SEP-TYR-ARG-LYS-ILE-LEU-ASN-ASP-LEU-SER-SER-ASP-ALA-PRO | 著者 | Zhang, K, Horikoshi, N, Li, S, Powers, A, Hameedi, M, Pintilie, G, Chae, H, Khan, Y, Suomivuori, C, Dror, R, Sakamoto, K, Chiu, W, Wakatsuki, S. | 登録日 | 2021-12-22 | 公開日 | 2022-03-16 | 実験手法 | ELECTRON MICROSCOPY (2.3 Å) | 主引用文献 | Cryo-EM, Protein Engineering, and Simulation Enable the Development of Peptide Therapeutics against Acute Myeloid Leukemia. Acs Cent.Sci., 8, 2022
|
|