PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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7ONB	Structure of the U2 5' module of the A3'-SSA complex 分子名称: MINX, PHD finger-like domain-containing protein 5A, RNU2, ... 著者 Cretu, C, Pena, V. 登録日 2021-05-25 公開日 2021-08-04 最終更新日 2024-11-20 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors. Nat Commun, 12, 2021
7XYG	Cryo-EM structure of Fft3-nucleosome complex with Fft3 bound to SHL+3 position of the nucleosome 分子名称: ATP-dependent helicase fft3, DNA (167-MER), Histone H2A, ... 著者 Nan, Z, Tao, J, Yangao, H. 登録日 2022-06-01 公開日 2023-12-06 最終更新日 2024-06-12 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Cryo-EM structure of Fft3-nucleosome complex with Fft3 bound to SHL+3 position of the nucleosome (Class II Fft3-nucleosome complex) To Be Published
3GSZ	Structure of the genotype 2B HCV polymerase 分子名称: RNA-directed RNA polymerase 著者 Rydberg, E.H, Carfi, A. 登録日 2009-03-27 公開日 2009-07-07 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural basis for resistance of the genotype 2b hepatitis C virus NS5B polymerase to site A non-nucleoside inhibitors. J.Mol.Biol., 390, 2009
2E1W	Crystal structure of adenosine deaminase complexed with potent inhibitors 分子名称: 1-{(1R,2S)-2-HYDROXY-1-[2-(1-NAPHTHYL)ETHYL]PROPYL}-1H-IMIDAZOLE-4-CARBOXAMIDE, Adenosine deaminase, ZINC ION 著者 Kinoshita, T. 登録日 2006-10-30 公開日 2006-11-07 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure-Based Design and Synthesis of Non-Nucleoside, Potent, and Orally Bioavailable Adenosine Deaminase Inhibitors J.Med.Chem., 47, 2004
8HXX	Cryo-EM structure of the histone deacetylase complex Rpd3S 分子名称: Chromatin modification-related protein EAF3, Histone H3, Histone deacetylase RPD3, ... 著者 Cui, H, Wang, H. 登録日 2023-01-05 公開日 2023-09-27 最終更新日 2024-11-06 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure of histone deacetylase complex Rpd3S bound to nucleosome. Nat.Struct.Mol.Biol., 30, 2023
7XYF	Cryo-EM structure of Fft3-nucleosome complex with Fft3 bound to SHL+2 position of the nucleosome 分子名称: ATP-dependent helicase fft3, DNA (167-MER), Histone H2A, ... 著者 Nan, Z, Tao, J, Yangao, H. 登録日 2022-06-01 公開日 2023-12-06 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structure of Fft3-nucleosome complex with Fft3 bound to SHL+2 position of the nucleosome (Class I Fft3-nucleosome complex) To Be Published
4UTP	Crystal structure of pneumococcal surface antigen PsaA in the Cd- bound, closed state 分子名称: CADMIUM ION, MANGANESE ABC TRANSPORTER SUBSTRATE-BINDING LIPOPROTEIN 著者 Luo, Z, Counago, R.M, Maher, M, Kobe, B. 登録日 2014-07-22 公開日 2014-08-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae. Nat Commun, 6, 2015
4UTO	Crystal structure of pneumococcal surface antigen PsaA D280N in the Cd-bound, open state 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CADMIUM ION, MANGANESE ABC TRANSPORTER SUBSTRATE-BINDING LIPOPROTEIN 著者 Luo, Z, Counago, R.M, Maher, M, Kobe, B. 登録日 2014-07-22 公開日 2015-03-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae. Nat Commun, 6, 2015
7YRD	histone methyltransferase 分子名称: DNA (146-MER), Histone H2A.Z, Histone H2B 1.1, ... 著者 Li, H, Wang, W.Y. 登録日 2022-08-09 公開日 2023-08-16 最終更新日 2025-07-02 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1. Mol.Cell, 83, 2023
1HNI	STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN A COMPLEX WITH THE NONNUCLEOSIDE INHIBITOR ALPHA-APA R 95845 AT 2.8 ANGSTROMS RESOLUTION 分子名称: (2-ACETYL-5-METHYLANILINO)(2,6-DIBROMOPHENYL)ACETAMIDE, HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66) 著者 Ding, J, Das, K, Arnold, E. 登録日 1995-02-28 公開日 1995-06-03 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution. Structure, 3, 1995
2GUT	Solution structure of the trans-activation domain of the human co-activator ARC105 分子名称: ARC/MEDIATOR, Positive cofactor 2 glutamine/Q-rich-associated protein 著者 Vought, B.W, Jim Sun, Z.-Y, Hyberts, S.G, Wagner, G, Naar, A.M. 登録日 2006-05-01 公開日 2006-08-08 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis. Nature, 442, 2006
1KV7	Crystal Structure of CueO, a multi-copper oxidase from E. coli involved in copper homeostasis 分子名称: COPPER (II) ION, CU-O-CU LINKAGE, PROBABLE BLUE-COPPER PROTEIN YACK 著者 Roberts, S.A, Weichsel, A, Grass, G, Thakali, K, Hazzard, J.T, Tollin, G, Rensing, C, Montfort, W.R. 登録日 2002-01-25 公開日 2002-02-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Crystal structure and electron transfer kinetics of CueO, a multicopper oxidase required for copper homeostasis in Escherichia coli. Proc.Natl.Acad.Sci.USA, 99, 2002
6TJ6	T. gondii myosin A trimeric complex with ELC1, calcium-free 分子名称: Calmodulin, putative, IMIDAZOLE, ... 著者 Pazicky, S, Loew, C. 登録日 2019-11-25 公開日 2020-10-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural role of essential light chains in the apicomplexan glideosome. Commun Biol, 3, 2020
6TJ5	T. gondii myosin A trimeric complex with ELC1 分子名称: CALCIUM ION, CHLORIDE ION, Calmodulin, ... 著者 Pazicky, S, Loew, C. 登録日 2019-11-25 公開日 2020-10-21 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.394 Å) 主引用文献 Structural role of essential light chains in the apicomplexan glideosome. Commun Biol, 3, 2020
6TJ4	P. falciparum essential light chain, N-terminal domain 分子名称: PfELC 著者 Pazicky, S, Loew, C. 登録日 2019-11-25 公開日 2020-10-21 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Structural role of essential light chains in the apicomplexan glideosome. Commun Biol, 3, 2020
1QXL	Crystal structure of Adenosine deaminase complexed with FR235380 分子名称: 1-((1R)-1-(HYDROXYMETHYL)-3-{6-[(5-PHENYLPENTANOYL)AMINO]-1H-INDOL-1-YL}PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE, Adenosine deaminase, ZINC ION 著者 Kinoshita, T. 登録日 2003-09-08 公開日 2004-09-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure-based design, synthesis, and structure-activity relationship studies of novel non-nucleoside adenosine deaminase inhibitors J.Med.Chem., 47, 2004
6LTH	Structure of human BAF Base module 分子名称: AT-rich interactive domain-containing protein 1A, SWI/SNF complex subunit SMARCC2, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, ... 著者 He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y. 登録日 2020-01-22 公開日 2020-02-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure of nucleosome-bound human BAF complex. Science, 367, 2020
7YRG	histone methyltransferase 分子名称: DNA (146-MER), Histone H2A.Z, Histone H2B 1.1, ... 著者 Li, H, Wang, W.Y. 登録日 2022-08-09 公開日 2023-12-13 最終更新日 2025-06-18 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Structural insight into H4K20 methylation on H2A.Z-nucleosome by SUV420H1. Mol.Cell, 83, 2023
1A4M	ADA STRUCTURE COMPLEXED WITH PURINE RIBOSIDE AT PH 7.0 分子名称: 6-HYDROXY-1,6-DIHYDRO PURINE NUCLEOSIDE, ADENOSINE DEAMINASE, ZINC ION 著者 Wang, Z, Quiocho, F.A. 登録日 1998-01-31 公開日 1998-10-14 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Complexes of adenosine deaminase with two potent inhibitors: X-ray structures in four independent molecules at pH of maximum activity. Biochemistry, 37, 1998
6WWD	Crystal structure of Nucleoside-triphosphatase / dITP/XTP pyrophosphatase from Mycobacterium abscessus ATCC 19977 / DSM 44196 分子名称: dITP/XTP pyrophosphatase 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2020-05-09 公開日 2020-05-20 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of Nucleoside-triphosphatase / dITP/XTP pyrophosphatase from Mycobacterium abscessus ATCC 19977 / DSM 44196 to be published
4J06	Crystal structure of hcv ns5b polymerase in complex with 2-{[(5-BROMOTHIOPHEN-2-YL)SULFONYL]AMINO}-4-CHLOROBENZOIC ACID 分子名称: 2-{[(5-bromothiophen-2-yl)sulfonyl]amino}-4-chlorobenzoic acid, Genome polyprotein 著者 Coulombe, R. 登録日 2013-01-30 公開日 2013-04-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of a novel series of non-nucleoside thumb pocket 2 HCV NS5B polymerase inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
4J02	Crystal structure of hcv ns5b polymerase in complex with [(1R)-5,8-DICHLORO-1-PROPYL-1,3,4,9-TETRAHYDROPYRANO[3,4-B]INDOL-1-YL]ACETIC ACID 分子名称: Genome polyprotein, SODIUM ION, SULFATE ION, ... 著者 Coulombe, R. 登録日 2013-01-30 公開日 2013-04-17 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of a novel series of non-nucleoside thumb pocket 2 HCV NS5B polymerase inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
4IZ0	Crystal structure of HCV NS5B polymerase in complex with 2,4,5-trichloro-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide 分子名称: 2,4,5-trichloro-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide, RNA-directed RNA polymerase 著者 Coulombe, R. 登録日 2013-01-29 公開日 2013-04-17 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Discovery of a novel series of non-nucleoside thumb pocket 2 HCV NS5B polymerase inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
4J04	Crystal structure of hcv ns5b polymerase in complex with 4-CHLORO-2-{[(2,4,5-TRICHLOROPHENYL)SULFONYL]AMINO}BENZOIC ACID 分子名称: 4-chloro-2-{[(2,4,5-trichlorophenyl)sulfonyl]amino}benzoic acid, Genome polyprotein, MANGANESE (II) ION 著者 Coulombe, R. 登録日 2013-01-30 公開日 2013-04-17 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Discovery of a novel series of non-nucleoside thumb pocket 2 HCV NS5B polymerase inhibitors. Bioorg.Med.Chem.Lett., 23, 2013
4J08	Crystal structure of hcv ns5b polymerase in complex with 2-{[(4-METHYLPHENYL)SULFONYL]AMINO}-5-PHENOXYBENZOIC ACID 分子名称: 2-{[(4-methylphenyl)sulfonyl]amino}-5-phenoxybenzoic acid, Genome polyprotein 著者 Coulombe, R. 登録日 2013-01-30 公開日 2013-04-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of a novel series of non-nucleoside thumb pocket 2 HCV NS5B polymerase inhibitors. Bioorg.Med.Chem.Lett., 23, 2013

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