2GUT

Solution structure of the trans-activation domain of the human co-activator ARC105

Summary for 2GUT

• Entry DOI: 10.2210/pdb2gut/pdb
• NMR Information: BMRB: 7185
• Descriptor: ARC/MEDIATOR, Positive cofactor 2 glutamine/Q-rich-associated protein (1 entity in total)
• Functional Keywords: kix, 3 helical bundle, transcription
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q96RN5
• Total number of polymer chains: 1
• Total formula weight: 8791.07

Authors

Vought, B.W.,Jim Sun, Z.-Y.,Hyberts, S.G.,Wagner, G.,Naar, A.M. (deposition date: 2006-05-01, release date: 2006-08-08, Last modification date: 2022-03-09)

• Primary citation: Yang, F.,Vought, B.W.,Satterlee, J.S.,Walker, A.K.,Jim Sun, Z.-Y.,Watts, J.L.,Debeaumont, R.,Mako Saito, R.,Hyberts, S.G.,Yang, S.,Macol, C.,Iyer, L.,Tjian, R.,van den Heuvel, S.,Hart, A.C.,Wagner, G.,Naar, A.M.; An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis.; Nature, 442:700-704, 2006; PubMed: 16799563; DOI: 10.1038/nature04942

Experimental method

SOLUTION NMR