1QXL

Crystal structure of Adenosine deaminase complexed with FR235380

Summary for 1QXL

Entry DOI	10.2210/pdb1qxl/pdb
Descriptor	Adenosine deaminase, ZINC ION, 1-((1R)-1-(HYDROXYMETHYL)-3-{6-[(5-PHENYLPENTANOYL)AMINO]-1H-INDOL-1-YL}PROPYL)-1H-IMIDAZOLE-4-CARBOXAMIDE, ... (4 entities in total)
Functional Keywords	beta barrel, zinc ion, hydrolase
Biological source	Bos taurus (cattle)
Cellular location	Cell membrane ; Peripheral membrane protein ; Extracellular side : P56658
Total number of polymer chains	1
Total formula weight	40865.68
Authors	Kinoshita, T. (deposition date: 2003-09-08, release date: 2004-09-21, Last modification date: 2024-03-13)
Primary citation	Terasaka, T.,Kinoshita, T.,Kuno, M.,Seki, N.,Tanaka, K.,Nakanishi, I. Structure-based design, synthesis, and structure-activity relationship studies of novel non-nucleoside adenosine deaminase inhibitors J.Med.Chem., 47:3730-3743, 2004 Cited by PubMed: 15239652 DOI: 10.1021/jm0306374 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation