4UTO

Crystal structure of pneumococcal surface antigen PsaA D280N in the Cd-bound, open state

Summary for 4UTO

Entry DOI	10.2210/pdb4uto/pdb
Related	4UTP
Descriptor	MANGANESE ABC TRANSPORTER SUBSTRATE-BINDING LIPOPROTEIN, CADMIUM ION, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (4 entities in total)
Functional Keywords	metal binding protein, atp binding, cassette transporter
Biological source	STREPTOCOCCUS PNEUMONIAE
Cellular location	Cell membrane ; Lipid-anchor : P0A4G2
Total number of polymer chains	2
Total formula weight	69745.68
Authors	Luo, Z.,Counago, R.M.,Maher, M.,Kobe, B. (deposition date: 2014-07-22, release date: 2015-03-11, Last modification date: 2024-01-10)
Primary citation	Begg, S.L.,Eijkelkamp, B.A.,Luo, Z.,Counago, R.M.,Morey, J.R.,Maher, M.J.,Ong, C.L.,McEwan, A.G.,Kobe, B.,O'Mara, M.L.,Paton, J.C.,McDevitt, C.A. Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae. Nat Commun, 6:6418-6418, 2015 Cited by PubMed: 25731976 DOI: 10.1038/ncomms7418 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.55 Å)

Structure validation