PDB: 597 件ウェブページステータス検索Chemie searchBIRD

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5E7M	Crystal structure of the active catalytic core of the human DEAD-box protein DDX3 bound to AMPPNP 分子名称: ATP-dependent RNA helicase DDX3X, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER 著者 Floor, S.N, Condon, K.J, Doudna, J.A. 登録日 2015-10-12 公開日 2015-12-02 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.304 Å) 主引用文献 Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3. J.Biol.Chem., 291, 2016
5E7J	Crystal structure of the active catalytic core of the human DEAD-box protein DDX3 bound to AMP 分子名称: ADENOSINE MONOPHOSPHATE, ATP-dependent RNA helicase DDX3X 著者 Floor, S.N, Condon, K.J, Doudna, J.A. 登録日 2015-10-12 公開日 2015-12-02 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3. J.Biol.Chem., 291, 2016
5ELX	S. cerevisiae Dbp5 bound to RNA and mant-ADP BeF3 分子名称: ATP-dependent RNA helicase DBP5, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ... 著者 Merchant, M.K, Modis, Y. 登録日 2015-11-05 公開日 2016-02-24 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Pi Release Limits the Intrinsic and RNA-Stimulated ATPase Cycles of DEAD-Box Protein 5 (Dbp5). J.Mol.Biol., 428, 2016
5F9H	Crystal structure of RIG-I helicase-RD in complex with 24-mer 5' triphosphate hairpin RNA 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX58, ... 著者 Wang, C, Marcotrigiano, J, Miller, M, Jiang, F. 登録日 2015-12-09 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I. Proc.Natl.Acad.Sci.USA, 113, 2016
5F9F	Crystal structure of RIG-I helicase-RD in complex with 24-mer blunt-end hairpin RNA 分子名称: (R,R)-2,3-BUTANEDIOL, MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX58, ... 著者 Wang, C, Marcotrigiano, J, Miller, M.T, Jiang, F. 登録日 2015-12-09 公開日 2016-01-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.601 Å) 主引用文献 Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I. Proc.Natl.Acad.Sci.USA, 113, 2016
5F98	Crystal structure of RIG-I in complex with Cap-0 RNA 分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Probable ATP-dependent RNA helicase DDX58, ... 著者 Wang, C, Marcotrigiano, J, Miller, M, Jiang, F. 登録日 2015-12-09 公開日 2016-01-13 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.28 Å) 主引用文献 Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I. Proc.Natl.Acad.Sci.USA, 113, 2016
5GAN	The overall structure of the yeast spliceosomal U4/U6.U5 tri-snRNP at 3.7 Angstrom 分子名称: 13 kDa ribonucleoprotein-associated protein, GUANOSINE-5'-TRIPHOSPHATE, Pre-mRNA-processing factor 31, ... 著者 Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K. 登録日 2015-12-15 公開日 2016-01-27 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution. Nature, 530, 2016
5GAP	Body region of the U4/U6.U5 tri-snRNP 分子名称: 13 kDa ribonucleoprotein-associated protein, Pre-mRNA-processing factor 31, Pre-mRNA-splicing factor 6, ... 著者 Nguyen, T.H.D, Galej, W.P, Oubridge, C, Bai, X.C, Newman, A, Scheres, S, Nagai, K. 登録日 2015-12-15 公開日 2016-01-27 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution. Nature, 530, 2016
5GAO	Head region of the yeast spliceosomal U4/U6.U5 tri-snRNP 分子名称: Pre-mRNA-splicing factor 8, Pre-mRNA-splicing helicase BRR2, Saccharomyces cerevisiae strain UOA_M2 chromosome 5 sequence, ... 著者 Nguyen, T.H.D, Galej, W.P, Bai, X.C, Oubridge, C, Scheres, S.H.W, Newman, A.J, Nagai, K. 登録日 2015-12-15 公開日 2016-01-27 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution. Nature, 530, 2016
3JCM	Cryo-EM structure of the spliceosomal U4/U6.U5 tri-snRNP 分子名称: 13 kDa ribonucleoprotein-associated protein, GUANOSINE-5'-TRIPHOSPHATE, N,N,7-trimethylguanosine 5'-(trihydrogen diphosphate), ... 著者 Wan, R, Yan, C, Bai, R, Wang, L, Huang, M, Wong, C.C, Shi, Y. 登録日 2015-12-23 公開日 2016-02-24 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 The 3.8 angstrom structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis Science, 351, 2016
3JCR	3D structure determination of the human*U4/U6.U5* tri-snRNP complex 分子名称: LSm2, LSm3, LSm4, ... 著者 Agafonov, D.E, Kastner, B, Dybkov, O, Hofele, R.V, Liu, W.T, Urlaub, H, Luhrmann, R, Stark, H. 登録日 2016-01-21 公開日 2016-03-09 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (7 Å) 主引用文献 Molecular architecture of the human U4/U6.U5 tri-snRNP. Science, 351, 2016
5I8Q	S. cerevisiae Prp43 in complex with RNA and ADPNP 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43, ... 著者 He, Y, Nielsen, K.H, Andersen, G.R. 登録日 2016-02-19 公開日 2017-02-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Structure of the DEAH/RHA ATPase Prp43p bound to RNA implicates a pair of hairpins and motif Va in translocation along RNA. RNA, 23, 2017
5JPT	CRYSTAL STRUCTURE OF THE PRP43P DEAH-BOX RNA HELICASE IN COMPLEX WITH CDP 分子名称: ACETATE ION, CYTIDINE-5'-DIPHOSPHATE, GLYCEROL, ... 著者 Robert-Paganin, J, Rety, S, Leulliot, N. 登録日 2016-05-04 公開日 2017-02-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.935 Å) 主引用文献 Functional link between DEAH/RHA helicase Prp43 activation and ATP base binding. Nucleic Acids Res., 45, 2017
5LBA	Crystal structure of human RECQL5 helicase in complex with DSPL fragment(1-cyclohexyl-3-(oxolan-2-ylmethyl)urea, SGC - Diamond XChem I04-1 fragment screening. 分子名称: 1-cyclohexyl-3-[[(2~{R})-oxolan-2-yl]methyl]urea, ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase Q5, ... 著者 Newman, J.A, Aitkenhead, H, Talon, R, Savitsky, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O, Structural Genomics Consortium (SGC) 登録日 2016-06-15 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of human RECQL5 helicase in complex with 3D fragment (1-cyclohexyl-3-(oxolan-2-ylmethyl)urea) To be published
5LB3	Crystal structure of human RECQL5 helicase in complex with ADP/Mg. 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase Q5, MAGNESIUM ION, ... 著者 Newman, J.A, Aitkenhead, H, Savitsky, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O, Structural Genomics Consortium (SGC) 登録日 2016-06-15 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5. Nucleic Acids Res., 45, 2017
5LB8	Crystal structure of human RECQL5 helicase APO form. 分子名称: ATP-dependent DNA helicase Q5, ZINC ION 著者 Newman, J.A, Aitkenhead, H, Savitsky, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O, Structural Genomics Consortium (SGC) 登録日 2016-06-15 公開日 2016-07-06 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5. Nucleic Acids Res., 45, 2017
5LB5	Crystal structure of human RECQL5 helicase in complex with ADP/Mg (tricilinc form). 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent DNA helicase Q5, DIMETHYL SULFOXIDE, ... 著者 Newman, J.A, Aitkenhead, H, Savitsky, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Gileadi, O, Structural Genomics Consortium (SGC) 登録日 2016-06-15 公開日 2016-07-06 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5. Nucleic Acids Res., 45, 2017
5GJU	DEAD-box RNA helicase 分子名称: ADENOSINE MONOPHOSPHATE, ATP-dependent RNA helicase DeaD 著者 Xu, L, Li, F, Wang, L, Shi, Y. 登録日 2016-07-02 公開日 2017-05-31 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions. Structure, 25, 2017
5GM6	Cryo-EM structure of the activated spliceosome (Bact complex) at 3.5 angstrom resolution 分子名称: ADENOSINE-5'-DIPHOSPHATE, Cold sensitive U2 snRNA suppressor 1, GUANOSINE-5'-TRIPHOSPHATE, ... 著者 Yan, C, Wan, R, Bai, R, Huang, G, Shi, Y. 登録日 2016-07-12 公開日 2016-09-21 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structure of a yeast activated spliceosome at 3.5 angstrom resolution Science, 353, 2016
5LJ5	Overall structure of the yeast spliceosome immediately after branching. 分子名称: CWC15, CWC22, Exon 1 (5' exon) of UBC4 pre-mRNA, ... 著者 Galej, W.P, Wilkinson, M.F, Fica, S.M, Oubridge, C, Newman, A.J, Nagai, K. 登録日 2016-07-17 公開日 2016-08-31 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Cryo-EM structure of the spliceosome immediately after branching. Nature, 537, 2016
5SUQ	Crystal structure of the THO-Sub2 complex 分子名称: 12-TUNGSTOPHOSPHATE, ATP-dependent RNA helicase SUB2, Tex1, ... 著者 Ren, Y, Blobel, G. 登録日 2016-08-03 公開日 2017-01-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (6 Å) 主引用文献 Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1. Elife, 6, 2017
5SUP	Crystal structure of the Sub2-Yra1 complex in association with RNA 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase SUB2, BERYLLIUM TRIFLUORIDE ION, ... 著者 Ren, Y, Schmiege, P, Blobel, G. 登録日 2016-08-03 公開日 2017-01-18 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1. Elife, 6, 2017
5LQW	yeast activated spliceosome 分子名称: Pre-mRNA leakage protein 1, Pre-mRNA-processing protein 45, Pre-mRNA-splicing factor 8, ... 著者 Rauhut, R, Luehrmann, R. 登録日 2016-08-17 公開日 2016-10-05 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (5.8 Å) 主引用文献 Molecular architecture of the Saccharomyces cerevisiae activated spliceosome Science, 6306, 2016
5LST	Crystal structure of the human RecQL4 helicase. 分子名称: ATP-dependent DNA helicase Q4, ZINC ION 著者 Kaiser, S, Sauer, F, Kisker, C. 登録日 2016-09-05 公開日 2017-07-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 The structural and functional characterization of human RecQ4 reveals insights into its helicase mechanism. Nat Commun, 8, 2017
5GVS	Crystal structure of the DDX41 DEAD domain in an apo open form 分子名称: Probable ATP-dependent RNA helicase DDX41 著者 Omura, H, Oikawa, D, Nakane, T, Kato, M, Ishii, R, Goto, Y, Suga, H, Ishitani, R, Tokunaga, F, Nureki, O. 登録日 2016-09-06 公開日 2016-10-19 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide Sci Rep, 6, 2016

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