5E7I
Crystal structure of the active catalytic core of the human DEAD-box protein DDX3
Summary for 5E7I
| Entry DOI | 10.2210/pdb5e7i/pdb |
| Related | 5E7J 5E7M |
| Descriptor | ATP-dependent RNA helicase DDX3X (1 entity in total) |
| Functional Keywords | dead-box protein, rna helicase, reca fold, hydrolase |
| Biological source | Homo sapiens (Human) |
| Cellular location | Nucleus speckle: O00571 |
| Total number of polymer chains | 3 |
| Total formula weight | 153276.00 |
| Authors | Floor, S.N.,Condon, K.J.,Doudna, J.A. (deposition date: 2015-10-12, release date: 2015-12-02, Last modification date: 2024-03-06) |
| Primary citation | Floor, S.N.,Condon, K.J.,Sharma, D.,Jankowsky, E.,Doudna, J.A. Autoinhibitory Interdomain Interactions and Subfamily-specific Extensions Redefine the Catalytic Core of the Human DEAD-box Protein DDX3. J.Biol.Chem., 291:2412-2421, 2016 Cited by PubMed: 26598523DOI: 10.1074/jbc.M115.700625 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.223 Å) |
Structure validation
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