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1NU4
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U1A RNA binding domain at 1.8 angstrom resolution reveals a pre-organized C-terminal helix
分子名称: MAGNESIUM ION, MALONIC ACID, U1A RNA binding domain
著者Rupert, P.B, Xiao, H, Ferre-D'Amare, A.R.
登録日2003-01-30
公開日2003-02-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献U1A RNA-binding domain at 1.8 A resolution.
Acta Crystallogr.,Sect.D, 59, 2003
6XH0
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BU of 6xh0 by Molmil
Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM TBP6.9
分子名称: MAGNESIUM ION, TAR binding protein 6.9, TRANS-ACTIVATION RESPONSE ELEMENT
著者Chavali, S.S, Jenkins, J.L, Wedekind, J.E.
登録日2020-06-18
公開日2020-10-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
J.Biol.Chem., 295, 2020
6XH3
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BU of 6xh3 by Molmil
Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM TBP6.3
分子名称: TAR BINDING PROTEIN TBP 6.3, TRANS-ACTIVATION RESPONSE ELEMENT
著者Chavali, S.S, Jenkins, J.L, Wedekind, J.E.
登録日2020-06-18
公開日2020-10-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.353 Å)
主引用文献Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
J.Biol.Chem., 295, 2020
6XLV
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BU of 6xlv by Molmil
Crystal structure of leukemia-associated N196K mutant of U2AF65 bound to AdML splice site
分子名称: DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
著者Maji, D, Jenkins, J.L, Kielkopf, C.L.
登録日2020-06-29
公開日2020-10-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing.
J.Biol.Chem., 295, 2020
1NO8
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BU of 1no8 by Molmil
SOLUTION STRUCTURE OF THE NUCLEAR FACTOR ALY RBD DOMAIN
分子名称: ALY
著者Perez-Alvarado, G.C, Martinez-Yamout, M, Allen, M.M, Grosschedl, R, Dyson, H.J, Wright, P.E.
登録日2003-01-15
公開日2003-08-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structure of the Nuclear Factor ALY: Insights into Post-Transcriptional Regulatory and mRNA Nuclear Export Processes
Biochemistry, 42, 2003
1OPI
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BU of 1opi by Molmil
SOLUTION STRUCTURE OF THE THIRD RNA RECOGNITION MOTIF (RRM) OF U2AF65 IN COMPLEX WITH AN N-TERMINAL SF1 PEPTIDE
分子名称: SPLICING FACTOR SF1, SPLICING FACTOR U2AF 65 KDA SUBUNIT
著者Selenko, P, Gregorovic, G, Sprangers, R, Stier, G, Rhani, Z, Kramer, A, Sattler, M.
登録日2003-03-05
公開日2004-03-16
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP
Mol.Cell, 11, 2003
1OIA
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BU of 1oia by Molmil
U1A rnp domain 1-95
分子名称: U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A
著者Nagai, K, Evans, P.R.
登録日2003-06-12
公開日2003-06-26
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of the RNA-Binding Domain of the U1 Small Nuclear Ribonucleoprotein A
Nature, 348, 1990
1P1T
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BU of 1p1t by Molmil
NMR Structure of the N-terminal RRM domain of Cleavage stimulation factor 64 KDa subunit
分子名称: Cleavage stimulation factor, 64 kDa subunit
著者Perez-Canadillas, J.M, Varani, G.
登録日2003-04-14
公開日2003-08-12
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein
Embo J., 22, 2003
6GX6
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BU of 6gx6 by Molmil
Crystal structure of IMP3 RRM12 in complex with RNA (ACAC)
分子名称: 1,2-ETHANEDIOL, Insulin-like growth factor 2 mRNA-binding protein 3, PHOSPHATE ION, ...
著者Jia, M, Gut, H, Chao, A.J.
登録日2018-06-26
公開日2018-09-05
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of IMP3 RRM12 recognition of RNA.
RNA, 24, 2018
3G9C
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BU of 3g9c by Molmil
Crystal structure of the product Bacillus anthracis glmS ribozyme
分子名称: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, GLMS RIBOZYME, MAGNESIUM ION, ...
著者Strobel, S.A, Cochrane, J.C, Lipchock, S.V, Smith, K.D.
登録日2009-02-13
公開日2009-11-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and chemical basis for glucosamine 6-phosphate binding and activation of the glmS ribozyme
Biochemistry, 48, 2009
3G96
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Crystal structure of the Bacillus anthracis glmS ribozyme bound to MaN6P
分子名称: 2-amino-2-deoxy-6-O-phosphono-alpha-D-mannopyranose, GLMS RIBOZYME, MAGNESIUM ION, ...
著者Strobel, S.A, Cochrane, J.C, Lipchock, S.V, Smith, K.D.
登録日2009-02-12
公開日2009-11-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.01 Å)
主引用文献Structural and chemical basis for glucosamine 6-phosphate binding and activation of the glmS ribozyme
Biochemistry, 48, 2009
6XH1
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BU of 6xh1 by Molmil
Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM TBP6.7 mutant
分子名称: TAR binding protein mutant 6.7 Q48R/T50R, TRANS-ACTIVATION RESPONSE ELEMENT
著者Chavali, S.S, Jenkins, J.L, Wedekind, J.E.
登録日2020-06-18
公開日2020-10-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.601 Å)
主引用文献Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
J.Biol.Chem., 295, 2020
6XLW
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BU of 6xlw by Molmil
Crystal structure of U2AF65 bound to AdML splice site sequence
分子名称: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), GLYCEROL, ...
著者Maji, D, Jenkins, J.L, Kielkopf, C.L.
登録日2020-06-29
公開日2020-10-07
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing.
J.Biol.Chem., 295, 2020
3G8T
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BU of 3g8t by Molmil
Crystal structure of the G33A mutant Bacillus anthracis glmS ribozyme bound to GlcN6P
分子名称: 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, RNA (5'-R(*AP*(A2M)P*GP*CP*GP*CP*CP*AP*GP*AP*AP*CP*U)-3'), ...
著者Strobel, S.A, Cochrane, J.C, Lipchock, S.V, Smith, K.D.
登録日2009-02-12
公開日2009-11-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural and chemical basis for glucosamine 6-phosphate binding and activation of the glmS ribozyme
Biochemistry, 48, 2009
6XH2
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BU of 6xh2 by Molmil
Co-crystal structure of HIV-1 TAR RNA in complex with lab-evolved RRM 6.6
分子名称: TAR-BINDING PROTEIN 6.6, TRANS-ACTIVATION RESPONSE ELEMENT
著者Chavali, S.S, Jenkins, J.L, Wedekind, J.E.
登録日2020-06-18
公開日2020-10-14
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors.
J.Biol.Chem., 295, 2020
6XLX
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BU of 6xlx by Molmil
Crystal structure of cancer-associated G301D mutant of U2AF65 bound to AdML splice site
分子名称: DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
著者Maji, D, Jenkins, J.L, Kielkopf, C.L.
登録日2020-06-29
公開日2020-10-07
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing.
J.Biol.Chem., 295, 2020
1O0P
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BU of 1o0p by Molmil
Solution Structure of the third RNA Recognition Motif (RRM) of U2AF65 in complex with an N-terminal SF1 peptide
分子名称: Splicing Factor SF1, Splicing factor U2AF 65 kDa subunit
著者Selenko, P, Gregorovic, G, Sprangers, R, Stier, G, Rhani, Z, Kramer, A, Sattler, M.
登録日2003-02-24
公開日2003-05-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural Basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP
Mol.Cell, 11, 2003
6HIP
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BU of 6hip by Molmil
Structure of SPF45 UHM bound to HIV-1 Rev ULM
分子名称: HIV-1 Rev (41-49), SODIUM ION, Splicing factor 45, ...
著者Pabis, M, Corsini, L, Sattler, M.
登録日2018-08-30
公開日2019-03-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Modulation of HIV-1 gene expression by binding of a ULM motif in the Rev protein to UHM-containing splicing factors.
Nucleic Acids Res., 47, 2019
3EGZ
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BU of 3egz by Molmil
Crystal structure of an in vitro evolved tetracycline aptamer and artificial riboswitch
分子名称: 7-CHLOROTETRACYCLINE, MAGNESIUM ION, Tetracycline aptamer and artificial riboswitch, ...
著者Xiao, H, Edwards, T.E, Ferre-D'Amare, A.R.
登録日2008-09-11
公開日2008-10-28
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis for specific, high-affinity tetracycline binding by an in vitro evolved aptamer and artificial riboswitch
Chem.Biol., 15, 2008
1RKJ
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BU of 1rkj by Molmil
Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target
分子名称: 5'-R(*GP*GP*AP*UP*GP*CP*CP*UP*CP*CP*CP*GP*AP*GP*UP*GP*CP*AP*UP*CP*C)-3', Nucleolin
著者Johansson, C, Finger, L.D, Trantirek, L, Mueller, T.D, Kim, S, Laird-Offringa, I.A, Feigon, J.
登録日2003-11-21
公開日2004-04-27
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of the complex formed by the two N-terminal RNA-binding domains of nucleolin and a pre-rRNA target.
J.Mol.Biol., 337, 2004
3G8S
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BU of 3g8s by Molmil
Crystal structure of the pre-cleaved Bacillus anthracis glmS ribozyme
分子名称: GLMS RIBOZYME, MAGNESIUM ION, RNA (5'-R(*AP*(A2M)P*GP*CP*GP*CP*CP*AP*GP*AP*AP*CP*U)-3'), ...
著者Strobel, S.A, Cochrane, J.C, Lipchock, S.V, Smith, K.D.
登録日2009-02-12
公開日2009-11-03
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural and chemical basis for glucosamine 6-phosphate binding and activation of the glmS ribozyme
Biochemistry, 48, 2009
3HHN
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BU of 3hhn by Molmil
Crystal structure of class I ligase ribozyme self-ligation product, in complex with U1A RBD
分子名称: Class I ligase ribozyme, self-ligation product, MAGNESIUM ION, ...
著者Shechner, D.M, Grant, R.A, Bagby, S.C, Bartel, D.P.
登録日2009-05-15
公開日2009-11-24
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.987 Å)
主引用文献Crystal structure of the catalytic core of an RNA-polymerase ribozyme.
Science, 326, 2009
3HI9
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BU of 3hi9 by Molmil
The x-ray crystal structure of the first RNA recognition motif (RRM1) of the AU-rich element (ARE) binding protein HuR at 2.0 angstrom resolution
分子名称: ELAV-like protein 1
著者Benoit, R.M, Kallen, J.
登録日2009-05-19
公開日2010-03-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The X-ray Crystal Structure of the First RNA Recognition Motif and Site-Directed Mutagenesis Suggest a Possible HuR Redox Sensing Mechanism.
J.Mol.Biol., 397, 2010
1PO6
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BU of 1po6 by Molmil
Crystal Structure of UP1 Complexed With d(TAGG(6MI)TTAGGG): A Human Telomeric Repeat Containing 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine (6MI)
分子名称: 5'-D(*T*AP*GP*GP*(6MI)P*TP*TP*AP*GP*GP*G)-3', Heterogeneous nuclear ribonucleoprotein A1
著者Myers, J.C, Moore, S.A, Shamoo, Y.
登録日2003-06-13
公開日2003-11-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures
J.BIOL.CHEM., 278, 2003
6KOR
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BU of 6kor by Molmil
Crystal structure of the RRM domain of SYNCRIP
分子名称: Heterogeneous nuclear ribonucleoprotein Q
著者Chen, Y, Chan, J, Chen, W, Jobichen, C.
登録日2019-08-12
公開日2020-01-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.602 Å)
主引用文献SYNCRIP, a new player in pri-let-7a processing.
Rna, 26, 2020

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