PDB: 22634 件ウェブページステータス検索Chemie searchBIRD

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7NPT	Cytosolic bridge of an intact ESX-5 inner membrane complex 分子名称: ESX-5 secretion system protein EccC5, ESX-5 secretion system protein EccD5 著者 Fahrenkamp, D, Bunduc, C.M, Wald, J, Ummels, R, Bitter, W, Houben, E.N.G, Marlovits, T.C. 登録日 2021-02-28 公開日 2021-05-26 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.27 Å) 主引用文献 Structure and dynamics of a mycobacterial type VII secretion system. Nature, 593, 2021
6UW1	The crystal structure of FbiA from Mycobacterium Smegmatis, Fo bound form 分子名称: 1-deoxy-1-(8-hydroxy-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-D-ribitol, CALCIUM ION, Phosphoenolpyruvate transferase 著者 Grinter, R, Gillett, D, Cordero, P.R.F, Greening, C. 登録日 2019-11-04 公開日 2020-05-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.205 Å) 主引用文献 Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria. mSystems, 5, 2020
6UW7	The crystal structure of FbiA from Mycobacterium smegmatis, Dehydro-F420-0 bound form 分子名称: 2-[oxidanyl-[(2~{R},3~{S},4~{S})-2,3,4-tris(oxidanyl)-5-[2,4,8-tris(oxidanylidene)-1,9-dihydropyrimido[4,5-b]quinolin-10-yl]pentoxy]phosphoryl]oxyprop-2-enoic acid, CALCIUM ION, GLYCEROL, ... 著者 Grinter, R, Gillett, D, Cordero, P.R.F, Izore, T, Greening, C. 登録日 2019-11-04 公開日 2020-05-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.342 Å) 主引用文献 Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria. mSystems, 5, 2020
6UW3	The crystal structure of FbiA from Mycobacterium Smegmatis, GDP Bound form 分子名称: CALCIUM ION, GLYCEROL, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Grinter, R, Gillett, D, Cordero, P.R.F, Greening, C. 登録日 2019-11-04 公開日 2020-05-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria. mSystems, 5, 2020
6UVX	The crystal structure of FbiA from Mycobacterium Smegmatis, Apo state 分子名称: CALCIUM ION, Phosphoenolpyruvate transferase 著者 Grinter, R, Gillett, D, Cordero, P.R.F, Greening, C. 登録日 2019-11-04 公開日 2020-05-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria. mSystems, 5, 2020
6UW5	The crystal structure of FbiA from Mycobacterium smegmatis, GDP and Fo bound form 分子名称: 1-deoxy-1-(8-hydroxy-2,4-dioxo-3,4-dihydropyrimido[4,5-b]quinolin-10(2H)-yl)-D-ribitol, CALCIUM ION, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Grinter, R, Gillett, D, Cordero, P.R.F, Greening, C. 登録日 2019-11-04 公開日 2020-05-13 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria. mSystems, 5, 2020
7SHW	Crystal structure of Mycobacterium smegmatis LmcA with xenon 分子名称: GLYCEROL, LmcA, XENON 著者 Patel, O, Lucet, I, Panjikar, S. 登録日 2021-10-11 公開日 2022-04-13 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Crystal structure of the putative cell-wall lipoglycan biosynthesis protein LmcA from Mycobacterium smegmatis. Acta Crystallogr D Struct Biol, 78, 2022
8HCR	Cryo-EM structure of the Mycobacterium tuberculosis cytochrome bcc:aa3 supercomplex and a novel inhibitor targeting subunit cytochrome cI 分子名称: CYTOCHROME AA3 SUBUNIT CtaC, CYTOCHROME AA3 SUBUNIT CtaJ, Cytochrome bc1 complex Rieske iron-sulfur subunit, ... 著者 Mathiyazakan, V, Gruber, G. 登録日 2022-11-02 公開日 2023-05-03 最終更新日 2023-09-13 実験手法 ELECTRON MICROSCOPY 主引用文献 Cryo-Electron Microscopy Structure of the Mycobacterium tuberculosi s Cytochrome bcc : aa 3 Supercomplex and a Novel Inhibitor Targeting Subunit Cytochrome c I. Antimicrob.Agents Chemother., 67, 2023
6S0S	The crystal structure of kanamycin B dioxygenase (KanJ) from Streptomyces kanamyceticus in complex with nickel, ribostamycin B and 2-oxoglutarate 分子名称: 2-OXOGLUTARIC ACID, CHLORIDE ION, Kanamycin B dioxygenase, ... 著者 Mrugala, B, Porebski, P.J, Niedzialkowska, E, Minor, W, Borowski, T. 登録日 2019-06-18 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A study on the structure, mechanism, and biochemistry of kanamycin B dioxygenase (KanJ)-an enzyme with a broad range of substrates. Febs J., 288, 2021
6S0W	The crystal structure of kanamycin B dioxygenase (KanJ) from Streptomyces kanamyceticus in complex with nickel and kanamycin B sulfate 分子名称: (1R,2S,3S,4R,6S)-4,6-DIAMINO-3-[(3-AMINO-3-DEOXY-ALPHA-D-GLUCOPYRANOSYL)OXY]-2-HYDROXYCYCLOHEXYL 2,6-DIAMINO-2,6-DIDEOXY-ALPHA-D-GLUCOPYRANOSIDE, DI(HYDROXYETHYL)ETHER, Kanamycin B dioxygenase, ... 著者 Mrugala, B, Niedzialkowska, E, Minor, W, Borowski, T. 登録日 2019-06-18 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.36 Å) 主引用文献 A study on the structure, mechanism, and biochemistry of kanamycin B dioxygenase (KanJ)-an enzyme with a broad range of substrates. Febs J., 288, 2021
6HWH	Structure of a functional obligate respiratory supercomplex from Mycobacterium smegmatis 分子名称: CARDIOLIPIN, COPPER (II) ION, Co-purified unknown peptide built as polyALA, ... 著者 Wiseman, B, Nitharwal, R.G, Fedotovskaya, O, Schafer, J, Guo, H, Kuang, Q, Benlekbir, S, Sjostrand, D, Adelroth, P, Rubinstein, J.L, Brzezinski, P, Hogbom, M. 登録日 2018-10-12 公開日 2018-11-07 最終更新日 2019-11-06 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of a functional obligate complex III2IV2respiratory supercomplex from Mycobacterium smegmatis. Nat. Struct. Mol. Biol., 25, 2018
7AGT	Structure of the S726F mutant of AcylTransferase domain of Mycocerosic Acid Synthase from Mycobacterium tuberculosis acylated with Malonyl-coenzyme A 分子名称: MALONIC ACID, Mycocerosic acid synthase 著者 Brison, Y, Mourey, L, Maveyraud, L. 登録日 2020-09-23 公開日 2020-12-16 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.901 Å) 主引用文献 Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases. Acs Chem.Biol., 15, 2020
7O6E	2.12 A cryo-EM structure of Mycobacterium tuberculosis Ferritin 分子名称: Ferritin BfrB 著者 Gijsbers, A, Zhang, Y, Gao, Y, Peters, P.J, Ravelli, R.B.G. 登録日 2021-04-10 公開日 2021-05-19 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.1 Å) 主引用文献 Mycobacterium tuberculosis ferritin: a suitable workhorse protein for cryo-EM development. Acta Crystallogr D Struct Biol, 77, 2021
6S0V	The crystal structure of kanamycin B dioxygenase (KanJ) from Streptomyces kanamyceticus in complex with nickel, neamine and sulfate 分子名称: (1R,2R,3S,4R,6S)-4,6-diamino-2,3-dihydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside, Kanamycin B dioxygenase, NICKEL (II) ION, ... 著者 Mrugala, B, Niedzialkowska, E, Minor, W, Borowski, T. 登録日 2019-06-18 公開日 2020-07-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A study on the structure, mechanism, and biochemistry of kanamycin B dioxygenase (KanJ)-an enzyme with a broad range of substrates. Febs J., 288, 2021
4KB5	Crystal structure of MycP1 from Mycobacterium smegmatis 分子名称: GLYCEROL, Membrane-anchored mycosin mycp1 著者 Sun, D.M, He, Y, Tian, C.L. 登録日 2013-04-23 公開日 2014-02-05 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The putative propeptide of MycP1 in mycobacterial type VII secretion system does not inhibit protease activity but improves protein stability. Protein Cell, 4, 2013
7B7J	EccD5 ubiqutin like domain from Mycobacterium xenopi 分子名称: Secretion protein Snm4 著者 Beckham, K.S, Wilmanns, M. 登録日 2020-12-10 公開日 2021-07-07 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 Structure of the mycobacterial ESX-5 type VII secretion system pore complex. Sci Adv, 7, 2021
5KZF	Crystal structure of near full-length hexameric Mycobacterium tuberculosis proteasomal ATPase Mpa in apo form 分子名称: Proteasome-associated ATPase 著者 Li, H, Hu, K, Yang, S, Bai, L. 登録日 2016-07-25 公開日 2017-05-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.49 Å) 主引用文献 Mycobacterium tuberculosis proteasomal ATPase Mpa has a beta-grasp domain that hinders docking with the proteasome core protease. Mol. Microbiol., 105, 2017
8OVD	Respiratory supercomplex (III2-IV2) from Mycobacterium smegmatis 分子名称: (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate, (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... 著者 Kovalova, T, Krol, S, Sjostrand, D, Riepl, D, Gamiz-Hernandez, A, Brzezinski, P, Kaila, V, Hogbom, M. 登録日 2023-04-25 公開日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Long-range charge transfer mechanism of the III 2 IV 2 mycobacterial supercomplex. Nat Commun, 15, 2024
8OVC	Respiratory supercomplex (III2-IV2) from Mycobacterium smegmatis 分子名称: (1R)-2-(dodecanoyloxy)-1-[(phosphonooxy)methyl]ethyl tetradecanoate, (2R)-2-(hexadecanoyloxy)-3-{[(S)-hydroxy{[(1R,2R,3R,4R,5R,6S)-2,3,4,5,6-pentahydroxycyclohexyl]oxy}phosphoryl]oxy}propyl (9S)-9-methyloctadecanoate, (2S)-1-(hexadecanoyloxy)propan-2-yl (10S)-10-methyloctadecanoate, ... 著者 Kovalova, T, Krol, S, Sjostrand, D, Riepl, D, Gamiz-Hernandez, A, Brzezinski, P, Kaila, V, Hogbom, M. 登録日 2023-04-25 公開日 2024-07-17 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Long-range charge transfer mechanism of the III 2 IV 2 mycobacterial supercomplex. Nat Commun, 15, 2024
5IBD	Crystal structure Mycobacterium tuberculosis CYP121 in complex with inhibitor fragment 24a 分子名称: 4-(3'-amino[1,1'-biphenyl]-3-yl)-3-(4-methoxyphenyl)-1H-pyrazol-5-amine, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Levy, C. 登録日 2016-02-22 公開日 2016-04-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.77 Å) 主引用文献 Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors. J.Med.Chem., 59, 2016
6CCV	Crystal structure of a Mycobacterium smegmatis RNA polymerase transcription initiation complex with inhibitor Rifampicin 分子名称: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ... 著者 Lilic, M, Darst, S.A, Campbell, E.A. 登録日 2018-02-07 公開日 2018-08-15 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.05 Å) 主引用文献 Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nat Commun, 9, 2018
5IBF	Crystal structure Mycobacterium tuberculosis CYP121 in complex with inhibitor fragment 19a 分子名称: 4-(3'-amino[1,1'-biphenyl]-3-yl)-1H-pyrazol-5-amine, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Levy, C. 登録日 2016-02-22 公開日 2016-04-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors. J.Med.Chem., 59, 2016
5IBE	Crystal structure Mycobacterium tuberculosis CYP121 in complex with inhibitor fragment 25a 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 4-[5-amino-4-(3'-amino[1,1'-biphenyl]-3-yl)-1H-pyrazol-3-yl]phenol, Mycocyclosin synthase, ... 著者 Levy, C. 登録日 2016-02-22 公開日 2016-04-06 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.624 Å) 主引用文献 Fragment-Based Approaches to the Development of Mycobacterium tuberculosis CYP121 Inhibitors. J.Med.Chem., 59, 2016
6FOC	F1-ATPase from Mycobacterium smegmatis 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP synthase epsilon chain, ATP synthase gamma chain, ... 著者 Zhang, T, Montgomery, M.G, Leslie, A.G.W, Cook, G.M, Walker, J.E. 登録日 2018-02-06 公開日 2019-01-23 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (4 Å) 主引用文献 The structure of the catalytic domain of the ATP synthase fromMycobacterium smegmatisis a target for developing antitubercular drugs. Proc.Natl.Acad.Sci.USA, 116, 2019
4KM2	Crystal structure of Dihydrofolate reductase from Mycobacterium tuberculosis in an open conformation in complex with trimethoprim 分子名称: 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, Dihydrofolate reductase, TRIMETHOPRIM 著者 Dias, M.V.B, Tyrakis, P, Blundell, T.L. 登録日 2013-05-07 公開日 2013-12-25 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Mycobacterium tuberculosis Dihydrofolate Reductase Reveals Two Conformational States and a Possible Low Affinity Mechanism to Antifolate Drugs. Structure, 22, 2014

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