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7AGQ

Structure of the S726F mutant of AcylTransferase domain of Mycocerosic Acid Synthase from Mycobacterium tuberculosis

Summary for 7AGQ
Entry DOI10.2210/pdb7agq/pdb
Related7AGP 7AGR 7AGS 7AGT 7AGU
DescriptorMycocerosic acid synthase, ACETATE ION, GLYCEROL, ... (4 entities in total)
Functional Keywordsmycocerosic acid synthase, acyltransferase domain, polyketide synthase, mycobacterium tuberculosis, transferase
Biological sourceMycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Total number of polymer chains2
Total formula weight93271.21
Authors
Brison, Y.,Mourey, L.,Maveyraud, L. (deposition date: 2020-09-23, release date: 2020-12-16, Last modification date: 2024-01-31)
Primary citationGrabowska, A.D.,Brison, Y.,Maveyraud, L.,Gavalda, S.,Faille, A.,Nahoum, V.,Bon, C.,Guilhot, C.,Pedelacq, J.D.,Chalut, C.,Mourey, L.
Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases.
Acs Chem.Biol., 15:3206-3216, 2020
Cited by
PubMed: 33237724
DOI: 10.1021/acschembio.0c00772
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

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