6O6N

Structure of the regulator FasR from Mycobacterium tuberculosis in complex with C20-CoA

Summary for 6O6N

Entry DOI	10.2210/pdb6o6n/pdb
Descriptor	TetR family transcriptional regulator, Arachinoyl-CoA, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	tetr-like transcription factor, fatty acid biosynthesis regulation, transcription
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	22725.32
Authors	Larrieux, N.,Trajtenberg, F.,Lara, J.,Gramajo, H.,Buschiazzo, A. (deposition date: 2019-03-07, release date: 2020-03-11, Last modification date: 2024-03-13)
Primary citation	Lara, J.,Diacovich, L.,Trajtenberg, F.,Larrieux, N.,Malchiodi, E.L.,Fernandez, M.M.,Gago, G.,Gramajo, H.,Buschiazzo, A. Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine. Nat Commun, 11:3703-3703, 2020 Cited by PubMed: 32710080 DOI: 10.1038/s41467-020-17504-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation