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6O6P

Structure of the regulator FasR from Mycobacterium tuberculosis in complex with DNA

Summary for 6O6P
Entry DOI10.2210/pdb6o6p/pdb
DescriptorTetR family transcriptional regulator, DNA-forward, DNA-reverse (3 entities in total)
Functional Keywordstetr-like transcription factor, fatty acid biosynthesis regulation, transcription-dna complex, transcription/dna
Biological sourceMycobacterium tuberculosis
More
Total number of polymer chains4
Total formula weight69931.13
Authors
Larrieux, N.,Trajtenberg, F.,Lara, J.,Gramajo, H.,Buschiazzo, A. (deposition date: 2019-03-07, release date: 2020-03-11, Last modification date: 2023-10-11)
Primary citationLara, J.,Diacovich, L.,Trajtenberg, F.,Larrieux, N.,Malchiodi, E.L.,Fernandez, M.M.,Gago, G.,Gramajo, H.,Buschiazzo, A.
Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine.
Nat Commun, 11:3703-3703, 2020
Cited by
PubMed: 32710080
DOI: 10.1038/s41467-020-17504-x
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.851 Å)
Structure validation

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