7AGU

Structure of the S726F mutant of AcylTransferase domain of Mycocerosic Acid Synthase from Mycobacterium tuberculosis acylated with MethylMalonyl-coenzyme A

Summary for 7AGU

Entry DOI	10.2210/pdb7agu/pdb
Related	7AGP 7AGQ 7AGR 7AGS 7AGT
Descriptor	Mycocerosic acid synthase, METHYLMALONIC ACID, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	mycocerosic acid synthase, acyltransferase domain, polyketide synthase, mycobacterium tuberculosis, methylmalonyl-coenzyme a, transferase
Biological source	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
Total number of polymer chains	2
Total formula weight	93241.18
Authors	Brison, Y.,Mourey, L.,Maveyraud, L. (deposition date: 2020-09-23, release date: 2020-12-16, Last modification date: 2024-01-31)
Primary citation	Grabowska, A.D.,Brison, Y.,Maveyraud, L.,Gavalda, S.,Faille, A.,Nahoum, V.,Bon, C.,Guilhot, C.,Pedelacq, J.D.,Chalut, C.,Mourey, L. Molecular Basis for Extender Unit Specificity of Mycobacterial Polyketide Synthases. Acs Chem.Biol., 15:3206-3216, 2020 Cited by PubMed: 33237724 DOI: 10.1021/acschembio.0c00772 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation