8HCR
Cryo-EM structure of the Mycobacterium tuberculosis cytochrome bcc:aa3 supercomplex and a novel inhibitor targeting subunit cytochrome cI
Summary for 8HCR
| Entry DOI | 10.2210/pdb8hcr/pdb |
| EMDB information | 34664 |
| Descriptor | Cytochrome bc1 complex Rieske iron-sulfur subunit, FE2/S2 (INORGANIC) CLUSTER, PROTOPORPHYRIN IX CONTAINING FE, ... (13 entities in total) |
| Functional Keywords | cytochrome bcc:aa3 oxidase, mycobacterium tuberculosis, oxidoreductase |
| Biological source | Mycobacterium tuberculosis variant bovis BCG More |
| Total number of polymer chains | 18 |
| Total formula weight | 620764.09 |
| Authors | Mathiyazakan, V.,Gruber, G. (deposition date: 2022-11-02, release date: 2023-05-03, Last modification date: 2023-09-13) |
| Primary citation | Mathiyazakan, V.,Wong, C.F.,Harikishore, A.,Pethe, K.,Gruber, G. Cryo-Electron Microscopy Structure of the Mycobacterium tuberculosi s Cytochrome bcc : aa 3 Supercomplex and a Novel Inhibitor Targeting Subunit Cytochrome c I. Antimicrob.Agents Chemother., 67:e0153122-e0153122, 2023 Cited by PubMed: 37158740DOI: 10.1128/aac.01531-22 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY |
Structure validation
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