PDB: 20505 件ウェブページステータス検索Chemie searchBIRD

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5U9I	Crystal structure of the FKBP domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) complexed with S-farnesyl-L-cysteine methyl ester 分子名称: Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1), FARNESYL 著者 Yadav, R.P, Gakhar, L, Liping, Y, Artemyev, N.O. 登録日 2016-12-16 公開日 2017-07-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UEZ	BRD4_BD2_A-1342843 分子名称: 5-methoxy-2-methyl-6-(2-phenoxyphenyl)pyridazin-3(2H)-one, Bromodomain-containing protein 4 著者 Park, C.H. 登録日 2017-01-03 公開日 2017-05-10 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.51 Å) 主引用文献 Fragment-Based, Structure-Enabled Discovery of Novel Pyridones and Pyridone Macrocycles as Potent Bromodomain and Extra-Terminal Domain (BET) Family Bromodomain Inhibitors. J. Med. Chem., 60, 2017
5UGM	Crystal Structure of Human PPARgamma Ligand Binding Domain in Complex with Edaglitazone 分子名称: (5R)-5-({4-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]-1-benzothiophen-7-yl}methyl)-1,3-thiazolidine-2,4-dione, Peroxisome proliferator-activated receptor gamma, nonanoic acid 著者 Shang, J, Kojetin, D.J. 登録日 2017-01-09 公開日 2018-01-17 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPAR gamma. Elife, 7, 2018
5UGX	Crystal Structure of the Tyrosine Kinase Domain of FGF Receptor 2 Harboring a E565A/D650V double Gain-of-Function Mutation 分子名称: Fibroblast growth factor receptor 2, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... 著者 Mohammadi, M, Chen, H. 登録日 2017-01-10 公開日 2017-02-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.349 Å) 主引用文献 Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases. Elife, 6, 2017
5UGL	Crystal Structure of FGF Receptor 2 Tyrosine Kinase Domain Harboring the D650V Activating Mutation 分子名称: Fibroblast growth factor receptor 2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, SULFATE ION 著者 Mohammadi, M, Chen, H. 登録日 2017-01-09 公開日 2017-02-22 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.861 Å) 主引用文献 Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases. Elife, 6, 2017
5UL6	The molecular mechanisms by which NS1 of the 1918 Spanish influenza A virus hijack host protein-protein interactions 分子名称: Adapter molecule crk, Proline-rich motif of nonstructural protein 1 of influenza a virus 著者 Shen, Q, Zeng, D, Zhao, B, Li, P, Cho, J.H. 登録日 2017-01-24 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.45 Å) 主引用文献 The Molecular Mechanisms Underlying the Hijack of Host Proteins by the 1918 Spanish Influenza Virus. ACS Chem. Biol., 12, 2017
5VA0	Glucocorticoid Receptor DNA Binding Domain in complex with AP-1 response element from VCAM-1 Promoter 分子名称: DNA (5'-D(*CP*GP*GP*CP*TP*GP*AP*CP*TP*CP*AP*TP*CP*AP*AP*G)-3'), DNA (5'-D(*CP*TP*TP*GP*AP*TP*GP*AP*GP*TP*CP*AP*GP*CP*CP*G)-3'), Glucocorticoid receptor, ... 著者 Weikum, E.R, Ortlund, E.A. 登録日 2017-03-24 公開日 2017-08-09 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.295 Å) 主引用文献 Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes. Nucleic Acids Res., 45, 2017
5SXS	Crystal structure of catalase-peroxidase KatG with isonicotinic acid hydrazide and AMP bound 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, ... 著者 Loewen, P.C. 登録日 2016-08-10 公開日 2016-09-07 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.887 Å) 主引用文献 Isonicotinic acid hydrazide conversion to Isonicotinyl-NAD by catalase-peroxidases. J. Biol. Chem., 285, 2010
5TBG	The Solution Structure of the Magnesium-bound Conantokin-R1B Mutant 分子名称: Conantokin-R1B 著者 Castellino, F.J, Yuan, Y. 登録日 2016-09-12 公開日 2017-06-28 最終更新日 2019-12-04 実験手法 SOLUTION NMR 主引用文献 Discerning the Role of the Hydroxyproline Residue in the Structure of Conantokin Rl-B and Its Role in GluN2B Subunit-Selective Antagonistic Activity toward N-Methyl-d-Aspartate Receptors. Biochemistry, 55, 2016
5U6Z	Crystal Structure of Xenopus laevis Apex2 C-terminal Znf-GRF Domain 分子名称: DNA-(apurinic or apyrimidinic site) lyase, SULFATE ION, ZINC ION 著者 Wallace, B.D, Williams, R.S. 登録日 2016-12-09 公開日 2017-01-11 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 APE2 Zf-GRF facilitates 3'-5' resection of DNA damage following oxidative stress. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UHT	Structure of the Thermotoga maritima HK853-BeF3-RR468 complex at pH 5.0 分子名称: ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, MAGNESIUM ION, ... 著者 Liu, Y, Rose, J, Jiang, L, Zhou, P. 登録日 2017-01-12 公開日 2017-12-27 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.68 Å) 主引用文献 A pH-gated conformational switch regulates the phosphatase activity of bifunctional HisKA-family histidine kinases. Nat Commun, 8, 2017
5TBQ	The Solution Structure of the Magnesium-bound Conantokin-R1B Mutant 分子名称: Conantokin 著者 Castellino, F.J, Yuan, Y. 登録日 2016-09-12 公開日 2017-06-28 最終更新日 2019-12-04 実験手法 SOLUTION NMR 主引用文献 Discerning the Role of the Hydroxyproline Residue in the Structure of Conantokin Rl-B and Its Role in GluN2B Subunit-Selective Antagonistic Activity toward N-Methyl-d-Aspartate Receptors. Biochemistry, 55, 2016
5TBR	The Solution Structure of the Magnesium-bound Conantokin-R1B Mutant 分子名称: Conantokin-R1-B 著者 Castellino, F.J, Yuan, Y. 登録日 2016-09-12 公開日 2017-06-28 最終更新日 2019-12-04 実験手法 SOLUTION NMR 主引用文献 Discerning the Role of the Hydroxyproline Residue in the Structure of Conantokin Rl-B and Its Role in GluN2B Subunit-Selective Antagonistic Activity toward N-Methyl-d-Aspartate Receptors. Biochemistry, 55, 2016
5UK9	Wild-type K-Ras(GCP) pH 6.5 分子名称: GLYCEROL, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Parker, J.A, Mattos, C. 登録日 2017-01-20 公開日 2018-01-10 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (1.887 Å) 主引用文献 K-Ras Populates Conformational States Differently from Its Isoform H-Ras and Oncogenic Mutant K-RasG12D. Structure, 26, 2018
5UOI	Solution structure of the de novo mini protein HHH_rd1_0142 分子名称: HHH_rd1_0142 著者 Houliston, S, Rocklin, G.J, Lemak, A, Carter, L, Chidyausiku, T.M, Baker, D, Arrowsmith, C.H. 登録日 2017-01-31 公開日 2017-07-26 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Global analysis of protein folding using massively parallel design, synthesis, and testing. Science, 357, 2017
5V2O	De Novo Design of Novel Covalent Constrained Meso-size Peptide Scaffolds with Unique Tertiary Structures 分子名称: 1,3,5-BENZENETRICARBOXYLIC ACID, GLYCEROL, NONAETHYLENE GLYCOL, ... 著者 Dang, B, Wu, H, Mulligan, V.K, Mravic, M, Wu, Y, Lemmin, T, Ford, A, Silva, D, Baker, D, DeGrado, W.F. 登録日 2017-03-06 公開日 2017-10-04 最終更新日 2017-11-08 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5V35	Crystal structure of V71F mutant of the FKBP domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1) complexed with S-farnesyl-L-cysteine methyl ester 分子名称: Aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1), FARNESYL 著者 Yadav, R.P, Gakhar, L, Liping, Y, Artemyev, N.O. 登録日 2017-03-06 公開日 2017-07-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Unique structural features of the AIPL1-FKBP domain that support prenyl lipid binding and underlie protein malfunction in blindness. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VBG	Crystal Structure of full-length LpoA, Monoclinic form 1, from Haemophilus influenzae 分子名称: CHLORIDE ION, Penicillin-binding protein activator LpoA 著者 Sathiyamoorthy, K, Saper, M.A. 登録日 2017-03-29 公開日 2017-09-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural analyses of the Haemophilus influenzae peptidoglycan synthase activator LpoA suggest multiple conformations in solution. J. Biol. Chem., 292, 2017
5VAT	Haemophilus influenzae LpoA: Monoclinic form (Mon2) with 2 molecules per a.u. 分子名称: Penicillin-binding protein activator LpoA 著者 Saper, M.A, Sathiyamoorthy, K. 登録日 2017-03-27 公開日 2017-09-13 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural analyses of the Haemophilus influenzae peptidoglycan synthase activator LpoA suggest multiple conformations in solution. J. Biol. Chem., 292, 2017
5UV5	Crystal Structure of a 2-Hydroxyisoquinoline-1,3-dione RNase H Active Site Inhibitor with Multiple Binding Modes to HIV Reverse Transcriptase 分子名称: 7-(furan-2-yl)-2-hydroxyisoquinoline-1,3(2H,4H)-dione, MANGANESE (II) ION, Reverse transcriptase/ribonuclease H, ... 著者 Kirby, K.A, Sarafianos, S.G. 登録日 2017-02-19 公開日 2017-08-16 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A 2-Hydroxyisoquinoline-1,3-Dione Active-Site RNase H Inhibitor Binds in Multiple Modes to HIV-1 Reverse Transcriptase. Antimicrob. Agents Chemother., 61, 2017
5UJE	SbnI with C-terminal truncation from Staphylococcus aureus 分子名称: GLYCEROL, SbnI protein 著者 Murphy, M.E.P, Verstraete, M.M. 登録日 2017-01-17 公開日 2018-01-24 最終更新日 2020-12-30 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 SbnI is a free serine kinase that generates O -phospho-l-serine for staphyloferrin B biosynthesis in Staphylococcus aureus . J.Biol.Chem., 293, 2018
5UP4	Structure of the HIV-1 Capsid Protein and spacer peptide 1 by Cryo-EM 分子名称: HIV-1 Capsid Protein and spacer peptide 1 著者 Perilla, J.R, Schirra, R, Zhang, P, Schulten, K. 登録日 2017-02-01 公開日 2017-12-06 最終更新日 2017-12-13 実験手法 ELECTRON MICROSCOPY (9 Å) 主引用文献 Quenching protein dynamics interferes with HIV capsid maturation. Nat Commun, 8, 2017
5VA7	Glucocorticoid Receptor DNA Binding Domain - IL11 AP-1 recognition element Complex 分子名称: DNA (5'-D(*AP*GP*GP*GP*TP*GP*AP*GP*TP*CP*AP*GP*GP*AP*TP*G)-3'), DNA (5'-D(*CP*AP*TP*CP*CP*TP*GP*AP*CP*TP*CP*AP*CP*CP*CP*T)-3'), Glucocorticoid receptor, ... 著者 Weikum, E.R, Ortlund, E.A. 登録日 2017-03-24 公開日 2017-08-09 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.153 Å) 主引用文献 Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes. Nucleic Acids Res., 45, 2017
5VCB	Crystal structure of holo-(acyl-carrier-protein) synthase:holo(acyl-carrier-protein) complex from Escherichia Coli. 分子名称: 4'-PHOSPHOPANTETHEINE, Acyl carrier protein, Holo-[acyl-carrier-protein] synthase 著者 Marcella, A.M, Barb, A.W. 登録日 2017-03-31 公開日 2017-11-01 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Structure, High Affinity, and Negative Cooperativity of the Escherichia coli Holo-(Acyl Carrier Protein):Holo-(Acyl Carrier Protein) Synthase Complex. J. Mol. Biol., 429, 2017
5SXW	Crystal structure of the E198A variant of catalase-peroxidase KatG of Burkholderia pseudomallei 分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, Catalase-peroxidase, ... 著者 Loewen, P.C. 登録日 2016-08-10 公開日 2016-09-07 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Isonicotinic acid hydrazide conversion to Isonicotinyl-NAD by catalase-peroxidases. J. Biol. Chem., 285, 2010

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